Diagnostic modality used for confirmation of tuberculosis.

<p>Note: Primary diagnostic modality used diagnosis of tuberculosis.</p>*<p>Criteria for disease category given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">material and methods</a>.</p>¶<p>Imaging tests included chest×rays for pulmonary patients, CT scan and or MRI for disseminated disease.</p

Relationship of IFNγ and IL10 SNPs with mycobacterial antigen induced cytokine secretion.

<p>Whole blood from TB not affected (TBNA) Tuberculin skin test positive donors was stimulated with <i>M. tuberculosis</i> culture filtrate (CF) proteins [5 µg/ml] and supernatants tested at 2 days for IL10 secretion and day 5 for IFNγ secretion using ELISA method as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">material and methods</a>. Results are expressed as pg/ml after deducting secretion in un-stimulated whole blood.</p

Demographic characteristics of TB Patients and Controls.

<p><b>Note:</b> Patient stratification is as given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">Materials and Methods</a>. Abbreviations for groups are given in brackets. TBA included 10 previously treated patients.</p

Genotype frequencies in healthy controls and different clinical forms of tuberculosis (TB).

<p>Note: Patient stratification is given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">Materials and Methods</a>. N for each group given in brackets. Abbreviations used as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#pone-0004778-t001" target="_blank">Table 1</a>. Number (frequency) of genotypes is indicated. Pearson chi analysis was carried to determine the significance of differences.</p><p>All significant p values are indicated in bold. P approaching significance is given in italics. <i>p</i><0.05 is considered significant.</p

Genotype combination in relation to disease severity.

<p>Genotype combination in relation to disease severity.</p

Differences in allele frequencies in healthy controls and tuberculosis patients

<p>Note: Patient stratification is given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#s4" target="_blank">material and methods</a>. N for each group is given in brackets. Abbreviations used as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004778#pone-0004778-t001" target="_blank">Table 1</a>.</p