Osteoporosis prevention in postmenopausal female workers : Beneficial effects of silicon dietary supplementation on oxidative status. A pilot study

In the last years, the employment of ageing women is increased, and the well-being of these workers, together with the prevention of chronic disabling diseases, is an issue of great importance. Moreover, as postmenopausal ageing is associated with the loss of bone density and consequent increased fracture risk, promoting bone health in these women could be the best strategy for avoiding osteoporotic fractures. We aimed to evaluate the effects of 3-month supplementation with a commercial antioxidant product containing Silica on oxidative status and bone markers in a sample of Italian female workers. Subjects were menopausal and osteopenic women (N=29, age 59.34\ub16.37, mean BMI 26.19\ub14.01 kg/m2). At baseline (T0) and after three-month treatment (T1) bone mineral density (BMD) was evaluated by phalangeal osteosonogrammetry. Haematological, serum biochemical parameters, reactive oxygen species (ROS), total antioxidant capacity (TAC), oxydated low-density lipoproteins (oxLDL) and urinary cross-links pyridinoline (PYD) and deoxypyridinoline (DPD) were assessed. Parametric or non-parametric tests were performed at T0 and T1. To analyse the possible association between two variables a linear correlation test was performed. At T0, slightly high levels of ROS (86% of subjects), oxLDL (59%), Total Cholesterol (T-Chol) (90%) and LDL-Chol (59%) were observed, together with suboptimal or deficient 25-OH vitamin D (98%) concentrations. At T1, oxLDL levels and the ratio oxLDL/LDL-Chol significantly decreased (p<0.01). At T0 significant negative correlations between BMD T-score and cross-links were observed (DPD/Crea: r=-0.57, p=0.001; PYD/ Crea: r=-0.45, p=0.01). At T1, a significant reduction (p=0.03) was observed only for DPD (\u3bcg/L) but not for cross-links normalized by creatinine amounts. In conclusion 3-months Silica supplementation improves significantly oxidative status and bone resorption markers in most postmenopausal female workers, representing a complementary treatment for early phases of BMD reduction

Description d’une nouvelle esp\ue8ce du genre Platypria

Volume: 20Start Page: 49End Page: 5

Note sopra alcuni Carabici appartenenti al Museo Civico di Genova con descrizione di specie nuove

Volume: 7Start Page: 850End Page: 89

XVI. Esplorazione del Giuba e dei suoi affluenti compiuta dal Cap. V. Bottego durante gli anni 1892-93 sotto gli auspicii della Societ\ue0 Geografica Italiana. Risultati Zoologici. Coleotteri

Volume: 35Start Page: 247End Page: 47

Materiali per lo studio delle Hispidae: (Sul genere Brachispa, Appunti sul genere Xiphispa. Osservazioni sinonimiche sopra alcune Hispidae)

Volume: 3Start Page: 197End Page: 20

Appendice all\u27enumerazione dei Cetonidi raccolti nell\u27Arcipelago Malese e nella Papuasia dai signori G. Doria, O. Beccari e L.M. D\u27Albertis

Volume: 9Start Page: 83End Page: 11

Deux esp\ue8ces nouvelles de Hispides des \ueeles Natuna

Volume: 18Start Page: 201End Page: 20

A new species of the genus Ichthyurus

At the request of Mr. Ritsema I give here the description of a new Ichthyurus from Eastern Java, belonging to the collections of the Leyden Museum. The species of Ichthyurus at present known as inhabiting the island of Java are very few in number, and I have to thank Mr. Ritsema for entrusting me with the study of a very remarkable form of this highly interesting genus of Malacodermidae

Nuove contribuzioni allo studio dei Cetonidi Malesi e Papuani

Volume: 14Start Page: 5End Page: 1