10 research outputs found

    A Model Predictive Control Approach to Design a Parameterized Adaptive Cruise Control

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    Abstract The combination of different desirable characteristics and situation-dependent behavior cause the design of adaptive cruise control (ACC) systems to be time consuming and tedious. This chapter presents a systematic approach for the design and tuning of an ACC, based on model predictive control (MPC). A unique feature of the synthesized ACC is its parameterization in terms of the key characteristics safety, comfort and fuel economy. This makes it easy and intuitive to tune, even for nonexperts in (MPC) control, such as the driver. The effectiveness of the design approach is demonstrated using simulations for some relevant traffic scenarios

    SLO image (left) and corresponding OCT image of the retina pre and post induction of a vein occlusion.

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    <p>OCT showing the site of a venous occlusion. A- prior to the induction of a thrombus. B- shortly after the creation of a venous occlusion, the outer diameter of the vein increases in size. An area of hyperfluorescence appears in the upper portion of the vascular lumen corresponding to the area of fibrin deposition within the thrombus (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0162037#pone.0162037.g007" target="_blank">Fig 7</a>). In the lower portion, the area of hypofluorescence corresponds to a dense meshwork of erythrocytes, platelets and inflammatory cells. An associated serous detachment is also present, often appearing within 30 minutes of the induction of the occlusion. In panel C, 14 days after the induction of the thrombus, there is still retinal inflammation present as witnessed by hyper reflective dots in the retina and the vitreous. A partial posterior vitreous detachment is present containing a number of inflammatory cells and residual debris. The area around the vein is thinned as the outer retinal layers are reduced in size.</p

    Surgical set-up used to operate the animals.

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    <p>The Preceyes micromanipulator is positioned for this intervention for the right eye of a pig. The motion controller is handled by the surgeon, from the temporal side of the eye within the surgical field and well within reach of the eye itself. The surgeon remains in his standard operating room position. In his left hand, he is holding a handheld endoilluminator (free hand).</p

    Design schematic of the micromanipulator.

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    <p>Shown are the the various axes of rotation and degrees of freedom (DOF). The parallelogram mechanism kinematically constrains the instrument pivot to the entry point into the eye.</p

    Green epifluorescence (A 20X, B 10X) and H&E stain (C: 20X, D:10X) of a laser induced vascular occlusion.

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    <p>The eye was collected within 2 hours of the occlusion. Epifluorescence in the green channel confirms the presence of fibrin while the remainder of the thrombus is composed of a network of platelets and erythrocytes and inflammatory cells.</p

    Hematoxylin-eosin stain (A-5x, B-10X) of an occluded vessel.

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    <p>Damage to the surrounding retina and underlying choroid is clearly visible following laser extending beyond the limits of the vascular wall. However, the vascular lumen is occluded with limited damage to the vessel wall. Extensive choroidal hemorrhage indicates that considerable damage was also induced in the choroidal circulation.</p

    Day 14 fluorescein angiogram showing the presence of collateral vessels.

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    <p>Day 14 following a rose bengal induced venous occlusion in a pig eye. The formation of collateral vessels adjacent to the site of occlusion is clearly evident in this late frame angiogram. The site of occlusion is indicated by the arrow.</p
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