Examples of “somewhat, moderately, and marked stressful” daily incidents.

<p>Examples of “somewhat, moderately, and marked stressful” daily incidents.</p

Adjusted cross-correlation functions indicating that negative (“somewhat, moderately, and marked stressful”) incidents are associated with cyclic responses in urinary cortisol and urinary neopterin levels.

<p>Each lag represents a time interval of 12 h. Coefficients (bars) reaching the upper or lower confidence limits (lines) are significant at <i>p</i><.05. In <b>A</b>) negative incidents are followed by urinary cortisol concentration decreases at +lag 1 (12–24 h) and increases at +lag 6 (72–84 h). In <b>B</b>) negative incidents are preceded by urinary neopterin level increases at −lag 1 (0–12 h) and followed by urinary neopterin level decreases at +lag 4 (48–60 h).</p

Adjusted cross-correlation functions indicating that positive incidents related to “educational and/or social accomplishment” are associated with cyclic responses in urinary cortisol and urinary neopterin levels.

<p>Each lag represents a time interval of 12 h. Coefficients (bars) reaching the upper or lower confidence limits (lines) are significant at <i>p</i><.05. In <b>A</b>) positive incidents are followed by urinary cortisol concentration increases at ±lag 0 (0–12 h) and decreases at +lag 5 (60–72 h). In <b>B</b>) positive incidents are precipitated by urinary neopterin level decreases at −lag 2 (12–24 h) and followed by urinary neopterin level increases at +lag 1 (12–24 h).</p

Time series of urinary cortisol and urinary neopterin levels of the healthy woman under study.

<p><b>A</b>) shows the time series of urinary cortisol levels, and <b>B</b>) shows the time series of urinary neopterin levels. Both the raw data (solid black) and the fit from the ARIMA model representing the series' internal structure (dotted grey) are plotted. Time series cover a period of 63 days or 126 12-hour time-units during which the subject collected her entire urine in day portions (08:00–20:00 h, uneven numbers) and night portions (20:00–08:00 h, even numbers).</p