Prospectus, November 4, 1975

PC NEWS IN BRIEF: VETERAN, DID YOU KNOW?, CONCERT, X-COUNTRY NATIONALS; New road opens; FB team may bring fee increase; $50,000 in books missing; editorials; Letters To The Editor; Roots & Radicals; Committee to form; A Statement of Advertising Policy; Committee to form; ISSC Award Program Changes; Alice didn\u27t... on Wed.; Debate Team begins season; Play cast chosen; Distaff Side; Good News; Black Dance Presented; Speech Team Wins S.I.C.C.M. Tourey; New 3-Hour Course: Death and the Dying; Adult Diversion program; Champs are IM champs; Coach\u27s Corner; Basketball tryouts; Mudrock fires 170 at state golf meet; Sports Views; Burk resigns; Fast Freddy Winners; Fast Freddy\u27s football forecast; Let\u27s hear it for the Parkland Whatevers; PC women netters Spike Danville JC; Games Of November 8; The little old watchmaker at work in the space age; Dear Bonnie; PC News in brief Sign up for tourneys; College Representatives; Congratulations; Bonnie Raitt Plays; Vinyl Love; Country Bouquet; Kottke picks U of I; Foto-Funny\u27s; Reverse Discrimination?; 200 Years of navy; Classified; Club Notes: SNA meets..., Electronics Association; Far Out Planet; Skylines; Parkland Eventshttps://spark.parkland.edu/prospectus_1975/1003/thumbnail.jp

Prospectus, November 18, 1975

PC NEWS IN BRIEF: TOYS FOR TOTS, SHOPPING TRIP, KARATE, LOU HENSON, CHEERLEADERS, BIO 200; Hurry, 3 days remain; IKE…What?; Off Campus offering; P.C. Women 4th in State; editorial; Roots & Radicals; Far Out Planet; Letter To The Editor; Student Achievement Recognition Award; Some - Dancers?; Stick it in your...; P.M. Student Coffee Hour; Tickets Available; Aides to host tea For C-U Teachers; Introducing, Wes Crum; Distaff Side; \u27Why can\u27t we be friends?\u27; Dog Wash; EA to meet; First Meeting; Photo Contest; ERA Rally Held; (IBEA) Meeting Held; Good News; Louisiana Funk at its greatest; Purlie; Furor shakes up Stu-Go; Cited for misconduct: Three members suspended; Discord within Stu-Go: Conference under fire; Finance Board not doing job; Alternatives to Stu-Go; McMullen Resigns; Gameroom Brings Big money; Broken Record?; StuGo States Pinball Project Progresses; Skylines: Black holes?; Parkland Events; Students Not Fascists; Vinyl Love; B and O preforms; Country Bouquet: The Grand Ole Opry ; Dear Bonnie; Classified; Moondogs demolish Wrecks; Fast Freddy\u27s football forecast; I.M. Basketball starts today; Basketball schedule; Games of November 22; Coach\u27s Corner; Parkland Athletes Earn International Acclaim; Karate Demo set for Nov. 20; Ken needs you; Sports Views; Blackhawks vs Broadstreet Bullies at Chicago Stadiumhttps://spark.parkland.edu/prospectus_1975/1002/thumbnail.jp

Prospectus, October 21, 1975

PC NEWS IN BRIEF: FOOTBALL VOTE TODAY, HEALTH BROCHURES AVAILABLE, CANOE TRIP, BLOOD DRIVE, YOU CAN GRO; P.E. Building Ready by Christmas; New road to open; Faculty-Administration compromise: Midterm letter grades issued; editorials; Letters To The Editor; Roots & Radicals; McMullen vetoes jackets; Parkland Events; Career Room open to students; Tie-Rods named tug-of-war champs; Parkland Student directory; Football referendum set for October 22-23; LRC Suggestion Box; Distaff Side; Forum; Dear Bonnie; The Kaleidoscope; Zanies Here Today: Dinglefest Theatre; Football Results; Sports Views; Hendricks, Oliver to return: Cagers prepare for season; Fast Freddy\u27s football forecast; Games Of October 25; Coach\u27s Corner; Jocks; Intramurals: The People\u27s Sport; Lanphar to retire; P/C offers dog school; The Draft and YOU; Crosby and Nash Concert disappointing; Child development program starts; Vinyl Love; Foto-Funny\u27s; Country Bouquet; Bicentennial festivities announced: Celebration Week March 29-April 3; Bicent. Leadership Confab slated; Mini-concert; Local art for Bicentennial; Money still available from BEOG; folkorist October 23; Two plays to be presented in December; Classified; Club Notes: Vets Affairs..., I.O.C. Plans..., Rifle Club..., Lit Magazine...; Far Out Planet: Skylines; Scholarshp news from WIUhttps://spark.parkland.edu/prospectus_1975/1004/thumbnail.jp

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field