Additional file 1 of Electrophysiological characterization of a Cav3.2 calcium channel missense variant associated with epilepsy and hearing loss

Additional file 1. Supplementary material and methods

Additional file 1 of Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels

Additional file 1: Figure S1 (a) Time course of mibefradil mediated reversal of mechanical hypersensitivity in mice with a chronic constriction injury of the sciatic nerve. Statistical analyses were performed by two-way ANOVA followed by Tukey's test. Asterisks denote a significant difference of **P < 0.01 and ***P < 0.001 when compared with the control group (n = 5–7). Hashtags denote P < 0.001 for comparison with the sham-operated group. (b) Mibefradil at 10 mg/kg inhibits pain responses in CCI operated wild type mice, but not in Cav3.2 null mice *P < 0.05 and ***P < 0.001 (n = 5–6)