Intra-assay variability for biomarker concentrations determined using the Luminex® and Ella^TM platforms.

<p>Coefficient of variance (CV%) values for 156 sample assayed in duplicate by the Luminex® platform (shaded circles) and for 406–410 samples assayed by internal triplicate by the Ella^TM platform (open triangles). Analysis for sICAM-1 was excluded due to inappropriate dilution range. Graphs depict point estimates of the mean CV% and the corresponding 95% confidence intervals.</p

Bland-Altman bias representing difference in Log_e-transformed biomarker concentrations computed by Luminex® compared to the Ella^TM platform for values within dynamic range of both assays.

<p>Bland-Altman bias representing difference in Log_e-transformed biomarker concentrations computed by Luminex® compared to the Ella^TM platform for values within dynamic range of both assays.</p

Luminex® and Ella^TM multiplex platforms: dynamic range and limits of quantification for biomarkers of severe infection.

<p>Luminex® and Ella^TM multiplex platforms: dynamic range and limits of quantification for biomarkers of severe infection.</p

Relationship between raw untransformed concentration values obtained by the Luminex® compared to the Ella^TM platform.

<p>Spearman’s rho correlation coefficient (ρ) and p-values obtained using Spearman rank correlation for values (n) within assay dynamic range of both platforms.</p

The mean ratio of number of pages of pharmaceutical ads to number of pages of journal content (based on three issues per year, see text), 1970 to 2012.

<p>The mean ratio of number of pages of pharmaceutical ads to number of pages of journal content (based on three issues per year, see text), 1970 to 2012.</p

The mean number of pages of pharmaceutical ads, 2007 to 2012.

<p>The mean number of pages of pharmaceutical ads, 2007 to 2012.</p

General information regarding selected medical journals.

<p>General information regarding selected medical journals.</p

Journal revenue from pharmaceutical advertising.

<p>Journal revenue from pharmaceutical advertising.</p

The mean number of pages of pharmaceutical ads (based on three issues per year, see text), 1970 to 2012.

<p>The mean number of pages of pharmaceutical ads (based on three issues per year, see text), 1970 to 2012.</p

MOESM1 of Validation of parent-reported physical activity and sedentary time by accelerometry in young children

Additional file 1: Table S1. Questionnaire and accelerometer variable definitions for total physical activity