Spitzer Mid-Infrared Spectroscopy of Infrared Luminous Galaxies at z~2 III: Far-IR to Radio Properties and Optical Spectral Diagnostics

We present the far-IR, millimeter, and radio photometry as well as optical and near-IR spectroscopy of a sample of 48 z~1-3 Spitzer-selected ULIRGs with IRS mid-IR spectra. Our goals are to compute their bolometric emission, and to determine both the presence and relative strength of their AGN and starburst components. We find that strong-PAH sources tend to have higher 160um and 1.2mm fluxes than weak-PAH sources. The depth of the 9.7um silicate feature does not affect MAMBO detectability. We fit the far-IR SEDs of our sample and find an average ~7x10^{12}Lsun for our z>1.5 sources. Spectral decomposition suggests that strong-PAH sources typically have ~20-30% AGN fractions. Weak-PAH sources by contrast tend to have >~70% AGN fractions, with a few sources having comparable contributions of AGN and starbursts. The optical line diagnostics support the presence of AGN in the bulk of the weak-PAH sources. With one exception, our sources are narrow-line sources, show no obvious correspondence between the optical extinction and the silicate feature depth, and, in two cases, show evidence for outflows. Radio AGN are present in both strong-PAH and weak-PAH sources. This is supported by our sample's far-IR-to-radio ratios (q) being consistently below the average value of 2.34 for local star-forming galaxies. We use survival analysis to include the lower-limits given by the radio-undetected sources, arriving at =2.07+/-0.01 for our z>1.5 sample. In total, radio and, where available, optical line diagnostics support the presence of AGN in 57% of the z>1.5 sources, independent of IR-based diagnostics. For higher-z sources, the AGN luminosities alone are estimated to be >10^{12}Lsun, which, supported by the [OIII] luminosities, implies that the bulk of our sources host obscured quasars.Comment: 22 pages, 14 figures, accepted for publication in Ap

Nonergodic Behavior of Interacting Bosons in Harmonic Traps

We study the time evolution of a system of interacting bosons in a harmonic trap. In the low-energy regime, the quantum system is not ergodic and displays rather large fluctuations of the ground state occupation number. In the high energy regime of classical physics we find nonergodic behavior for modest numbers of trapped particles. We give two conditions that assure the ergodic behavior of the quantum system even below the condensation temperature.Comment: 11 pages, 3 PS-figures, uses psfig.st

The Spiderweb galaxy: a forming massive cluster galaxy at z~2

We present a deep image of the radio galaxy MRC 1138-262 taken with the Hubble Space Telescope (HST) at a redshift of z = 2.2. The galaxy is known to have properties of a cD galaxy progenitor and be surrounded by a 3 Mpc-sized structure, identified with a protocluster. The morphology shown on the new deep HST/ACS image is reminiscent of a spider's web. More than 10 individual clumpy features are observed, apparently star-forming satellite galaxies in the process of merging with the progenitor of a dominant cluster galaxy 11 Gyr ago. There is an extended emission component, implying that star formation was occurring over a 50 times 40 kpc region at a rate of more than 100 M_sun/yr. A striking feature of the newly named ``Spiderweb galaxy'' is the presence of several faint linear galaxies within the merging structure. The dense environments and fast galaxy motions at the centres of protoclusters may stimulate the formation of these structures, which dominate the faint resolved galaxy populations in the Hubble Ultra Deep Field. The new image provides a unique testbed for simulations of forming dominant cluster galaxies.Comment: 5 pages, 2 figures (reduced to grayscale); ApJ Letter

A tale of two classifier systems

This paper describes two classifier systems that learn. These are rule-based systems that use genetic algorithms, which are based on an analogy with natural selection and genetics, as their principal learning mechanism, and an economic model as their principal mechanism for apportioning credit. CFS-C is a domain-independent learning system that has been widely tested on serial computers. * CFS is a parallel implementation of CFS-C that makes full use of the inherent parallelism of classifier systems and genetic algorithms, and that allows the exploration of large-scale tasks that were formerly impractical. As with other approaches to learning, classifier systems in their current form work well for moderately-sized tasks but break down for larger tasks. In order to shed light on this issue, we present several empirical studies of known issues in classifier systems, including the effects of population size, the actual contribution of genetic algorithms, the use of rule chaining in solving higher-order tasks, and issues of task representation and dynamic population convergence. We conclude with a discussion of some major unresolved issues in learning classifier systems and some possible approaches to making them more effective on complex tasks.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46937/1/10994_2004_Article_BF00113895.pd

Time-like flows of energy-momentum and particle trajectories for the Klein-Gordon equation

The Klein-Gordon equation is interpreted in the de Broglie-Bohm manner as a single-particle relativistic quantum mechanical equation that defines unique time-like particle trajectories. The particle trajectories are determined by the conserved flow of the intrinsic energy density which can be derived from the specification of the Klein-Gordon energy-momentum tensor in an Einstein-Riemann space. The approach is illustrated by application to the simple single-particle phenomena associated with square potentials.Comment: 14 pages, 11 figure

Strong Lensing Analysis of A1689 from Deep Advanced Camera Images

We analyse deep multi-colour Advanced Camera images of the largest known gravitational lens, A1689. Radial and tangential arcs delineate the critical curves in unprecedented detail and many small counter-images are found near the center of mass. We construct a flexible light deflection field to predict the appearance and positions of counter-images. The model is refined as new counter-images are identified and incorporated to improve the model, yielding a total of 106 images of 30 multiply lensed background galaxies, spanning a wide redshift range, 1.0$<$z$<$5.5. The resulting mass map is more circular in projection than the clumpy distribution of cluster galaxies and the light is more concentrated than the mass within $r<50kpc/h$. The projected mass profile flattens steadily towards the center with a shallow mean slope of $d\log\Sigma/d\log r \simeq -0.55\pm0.1$, over the observed range, r$<250kpc/h$, matching well an NFW profile, but with a relatively high concentration, $C_{vir}=8.2^{+2.1}_{-1.8}$. A softened isothermal profile ($r_{core}=20\pm2$\arcs) is not conclusively excluded, illustrating that lensing constrains only projected quantities. Regarding cosmology, we clearly detect the purely geometric increase of bend-angles with redshift. The dependence on the cosmological parameters is weak due to the proximity of A1689, $z=0.18$, constraining the locus, $\Omega_M+\Omega_{\Lambda} \leq 1.2$. This consistency with standard cosmology provides independent support for our model, because the redshift information is not required to derive an accurate mass map. Similarly, the relative fluxes of the multiple images are reproduced well by our best fitting lens model.Comment: Accepted by ApJ. For high quality figures see http://wise-obs.tau.ac.il/~kerens/A168

Feedhorn-coupled TES polarimeter camera modules at 150 GHz for CMB polarization measurements with SPTpol

The SPTpol camera is a dichroic polarimetric receiver at 90 and 150 GHz. Deployed in January 2012 on the South Pole Telescope (SPT), SPTpol is looking for faint polarization signals in the Cosmic Microwave Background (CMB). The camera consists of 180 individual Transition Edge Sensor (TES) polarimeters at 90 GHz and seven 84-polarimeter camera modules (a total of 588 polarimeters) at 150 GHz. We present the design, dark characterization, and in-lab optical properties of the 150 GHz camera modules. The modules consist of photolithographed arrays of TES polarimeters coupled to silicon platelet arrays of corrugated feedhorns, both of which are fabricated at NIST-Boulder. In addition to mounting hardware and RF shielding, each module also contains a set of passive readout electronics for digital frequency-domain multiplexing. A single module, therefore, is fully functional as a miniature focal plane and can be tested independently. Across the modules tested before deployment, the detectors average a critical temperature of 478 mK, normal resistance R_N of 1.2 Ohm, unloaded saturation power of 22.5 pW, (detector-only) optical efficiency of ~ 90%, and have electrothermal time constants < 1 ms in transition.Comment: 15 pages, 11 figure

Learning to Decode the Surface Code with a Recurrent, Transformer-Based Neural Network

Quantum error-correction is a prerequisite for reliable quantum computation. Towards this goal, we present a recurrent, transformer-based neural network which learns to decode the surface code, the leading quantum error-correction code. Our decoder outperforms state-of-the-art algorithmic decoders on real-world data from Google's Sycamore quantum processor for distance 3 and 5 surface codes. On distances up to 11, the decoder maintains its advantage on simulated data with realistic noise including cross-talk, leakage, and analog readout signals, and sustains its accuracy far beyond the 25 cycles it was trained on. Our work illustrates the ability of machine learning to go beyond human-designed algorithms by learning from data directly, highlighting machine learning as a strong contender for decoding in quantum computers

Abrogation of Donor T Cell IL-21 Signaling Leads to Tissue-Specific Modulation of Immunity and Separation of GVHD From GVL

IL-21 is a proinflammatory cytokine produced by Th17 cells. Abrogation of IL-21 signaling has recently been shown to reduce GVHD while retaining graft-versus-leukemia/lymphoma (GVL) responses. However, the mechanisms by which IL-21 may lead to a separation of GVHD and GVL remain incompletely understood. In a murine MHC-mismatched BM transplantation model, we observed that IL-21 receptor knockout (IL-21R KO) donor T cells mediate decreased systemic and gastrointestinal GVHD in recipients of a transplant. This reduction in GVHD was associated with expansion of transplanted donor regulatory T cells and with tissue-specific modulation of Th-cell function. IL-21R KO and wild-type donor T cells showed equivalent alloactivation, but IL-21R KO T cells showed decreased infiltration and inflammatory cytokine production within the mesenteric lymph nodes. However, Th-cell cytokine production was maintained peripherally, and IL-21R KO T cells mediated equivalent immunity against A20 and P815 hematopoietic tumors. In summary, abrogation of IL-21 signaling in donor T cells leads to tissue-specific modulation of immunity, such that gastrointestinal GVHD is reduced, but peripheral T-cell function and GVL capacity are retained. IL-21 is thus an exciting target for therapeutic intervention and improvement of clinical transplantation outcomes

In vivo 18F-flortaucipir PET does not accurately support the staging of progressive supranuclear palsy

Progressive Supranuclear Palsy (PSP) is a neurodegenerative disorder characterised by neuro-glial tau pathology. A new staging system for PSP pathology at post-mortem has been described and validated. We used a data-driven approach to test whether post-mortem pathological staging in PSP can be reproduced in vivo with 18F-flortaucipir PET. Methods: N=42 patients with probable PSP and N=39 controls underwent 18F-flortaucipir PET. Conditional inference tree analyses on regional binding potential values identified absent/present pathology thresholds to define in vivo staging. Following the staging system for PSP pathology, the combination of absent/present values across all regions was evaluated to assign each participant to in vivo stages. Analysis of variance was applied to analyse differences among means of disease severity between stages. In vivo staging was compared with post-mortem staging in N=9 patients who also had post-mortem confirmation of the diagnosis and stage. Results: Stage assignment was estimable in 41 patients: N=10 patients were classified in stage I/II, N=26 in stage III/IV, N=5 in stage V/VI, while N=1 was not classifiable. An explorative sub-staging identified N=2 patients in stage I, N=8 in stage II, N=9 in stage III, N=17 in stage IV and N=5 in stage V. However, the nominal 18F-flortaucipir derived stage was not associated with clinical severity and was not indicative of pathology staging at post-mortem. Conclusion: 18F-flortaucipir PET in vivo does not correspond to neuropathological staging in PSP. This analytic approach, seeking to mirror in vivo the neuropathology staging with PET-to-autopsy correlational analyses might enable in vivo staging with next-generation PET tracers for tau, but further evidence and comparison with post-mortem data are needed.This study was co-funded by the Cambridge University Centre for Parkinson-Plus (RG95450); the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre (BRC-1215-20014), including their financial support for the Cambridge Brain Bank; the PSP Association (“MAPT-PSP” award); the Alzheimer’s Research UK East-Network pump priming grant; the Wellcome trust (220258); the Medical Research Council (MR/P01271X/1; G1100464); the Association of British Neurologists, Patrick Berthoud Charitable Trust (RG99368); Alzheimer’s Society (443 AS JF 18017); the Evelyn Trust (RG84654), and RCUK/UKRI (via a Research Innovation Fellowship awarded by the Medical Research Council to CHWG - MR/R007446/1); the Guarantors of Brain (G101149). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care