Pie Charts Showing Association between Repeat Arrays and Surface Proteins in FAM18

<p>Chart sectors are coloured according to gene function (see colour key).</p

Rearrangements between the Meningococcal Genomes

<p>The dotplots were generated using MUMmer version 3.15 (<a href="http://mummer.sourceforge.net" target="_blank">http://mummer.sourceforge.net</a>) and indicate matching sequences with codirectional and reversed regions of synteny shown in red and green, respectively. Genome sequences are aligned to start/finish at the origin of replication with the approximate position of the terminus of replication indicated (Ter) (note this required rotation of the publicly available sequences for Z2491 and MC58, see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030023#s3" target="_blank">Materials and Methods</a>). Also shown are the positions of the foci of the three major inversion events (IE1, IE2, and IE3, see text for detail).</p

NIME Array Percentage G + C Content Profile for an Array Located at 1283600–1284640 bp in the FAM18 Genome

<p>The % G + C window size is 24 bases. Maximum, minimum, and median are also shown. Red blocks represent dRS3 with inverted repeats indicated by grey triangles. Blue blocks represent RS elements.</p

Sequence Divergence in Orthologues Flanking Repeat Arrays<b> </b>

<div><p>(A) Plot of repeat array length against flanking orthologue sequence identity for FAM18 versus Z2491 (blue diamond), Z2491 versus MC58 (red square), and FAM18 versus MC58 (green triangle).</p><p>(B) Plot of distance from array versus orthologue identity for FAM18 versus Z2491, Z2491 versus MC58, and FAM18 versus MC58.</p><p>(C) The same as (B), ignoring the first CDS.</p></div