Factors Associated with Bovine Neonatal Pancytopenia (BNP) in Calves: A Case-Control Study

Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries during recent years. Data were retrospectively collected during June to November 2010 for 56 case calves diagnosed with BNP between 17 March and 7 June of the same year. These were compared with 58 control calves randomly recruited from herds with no history of BNP. Multivariable logistic regression analysis showed that increased odds of a calf being a BNP case were associated with its dam having received PregSure® BVD (Pfizer Animal Health) vaccination prior to the birth of the calf (odds ratio (OR) 40.78, p<0.001) and its herd of origin being located in Scotland (OR 9.71, p = 0.006). Decreased odds of a calf being a BNP case were associated with the calf having been kept outside (OR 0.11, p = 0.006). The longer that a cattle herd had been established on the farm was also associated with decreased odds of a calf in that herd being a BNP case (OR 0.97, p = 0.011)

Analysis of bovine viral diarrhoea virus: biobank and sequence database to support eradication in Scotland

Samples from bovine viral diarrhoea virus (BVDV)—positive cattle were gathered by Scottish diagnostic laboratories and used to produce a Biobank of samples with associated location and identification data in support of the Scottish BVDV eradication scheme. The samples were subject to direct amplification and sequencing of the 5′-untranslated region (5′-UTR) to define the viral types and subtypes present. From 2693 samples collected prior to 2016, approximately 2300 sequences were obtained, representing 8 BVDV type 1 subtypes. No BVDV type 2 samples were detected. The samples came from all regions of the UK but 66 per cent were from Scotland. Analysis of the sequences showed great diversity in the 5′-UTR, with 1206 different sequences. Many samples carried virus with identical 5′-UTR sequences; often from single locations, but there were also examples of the same sequence being obtained from samples at several different locations. This work provides a resource that can be used to analyse the movement of BVDV strains both within Scotland and between Scotland and other nations, particularly in the latter stages of the Scottish eradication programme, and so inform the advice available to both livestock keepers and policymakers

Information collected in the study questionnaire.

<p>Information collected in the study questionnaire.</p

Final logistic regression model of the factors significantly associated with a change in the odds of a calf being a BNP case.

<p>Final logistic regression model of the factors significantly associated with a change in the odds of a calf being a BNP case.</p

Breakdown of numbers of PregSure® BVD doses and their association with the likelihood of a calf being a BNP case.

<p>Breakdown of numbers of PregSure® BVD doses and their association with the likelihood of a calf being a BNP case.</p

E-government in a corporatist, communitarian society: The case of Singapore

10.1177/1461444806065661New Media and Society85707-73