802 research outputs found
The Empirical Research on the College Students’ Belief in Marxism——a Case Study of Chongqing, China
Abstract:Applying the empirical research method, this research investigated the current status of 575 Chongqing college students’ belief in Marxism. The results suggested that college students’ beliefve in Marxism had significant differences in gender, grade, academic performance and political status, college students’ cognition of Marxism affect their attitude. college students’ belief in Marxism is basically satisfactory, and universities need to strengthen belief education for different types of students
catena-Poly[[triaqua(pyridine-κN)nickel(II)]-μ-sulfato-κ2 O:O′]
The title compound, [Ni(SO4)(C5H5N)(H2O)3]n, was synthesized by the hydrothermal reaction of NiSO4·6H2O, pyridine and water. The central NiII atom is coordinated in a distorted octahedral environment by a pyridine N atom, three aqua O atoms and two O atoms of bridging sulfate anions, yielding a zigzag chain. A three-dimensional network is generated via complex hydrogen bonds involving the sulfate and aqua ligands and a pyridine C—H group
Spot Focusing Coma Correction by Linearly Polarized Dual-Transmitarray Antenna in the Terahertz Region
Focus scanning is critically important in many terahertz (THz) imaging and
sensing applications. A traditional single focusing transmitarray can achieve a
good focus when the source is on-axis but moving the source off-axis produces a
significant aberration. This paper presents a novel approach to reducing coma
in off-axis scanning in the THz region. Here, a dual transmitarray solution is
proposed, in which a transmitarray with an optimized phase profile is placed
behind a regular phase profile transmitarray. A linearly polarized,
dual-transmitarray antenna was fabricated for validation, and the focusing
performances were experimentally characterized. The measured results are in
good agreement with the theoretical ones. The generated spot of the
dual-transmitarray antenna remains focused on an angle up to 50deg, with a -3
dB spot size of less than 4 mm at 290 GHz. The measured near-field sidelobes
are all below -10 dB within the whole scanning range.Comment: 9 pages, 14 figure
Expression and distribution of PPP2R5C gene in leukemia
<p>Abstract</p> <p>Background</p> <p>Recently, we clarified at the molecular level novel chromosomal translocation t(14;14)(q11;q32) in a case of Sézary syndrome, which caused a rearrangement from TRAJ7 to the <it>PPP2R5C </it>gene. <it>PPP2R5C </it>is one of the regulatory B subunits of protein phosphatase 2A (PP2A). It plays a crucial role in cell proliferation, differentiation, and transformation. To characterize the expression and distribution of five different transcript variants of the <it>PPP2R5C </it>gene in leukemia, we analyzed the expression level of <it>PPP2R5C </it>in peripheral blood mononuclear cells from 77 patients with <it>de novo </it>leukemia, 26 patients with leukemia in complete remission (CR), and 20 healthy individuals by real-time PCR and identified the different variants of <it>PPP2R5C </it>by RT-PCR.</p> <p>Findings</p> <p>Significantly higher expression of <it>PPP2R5C </it>was found in AML, CML, T-ALL, and B-CLL groups in comparison with healthy controls. High expression of <it>PPP2R5C </it>was detected in the B-ALL group; however, no significant difference was found compared with the healthy group. The expression level of <it>PPP2R5C </it>in the CML-CR group decreased significantly compared with that in the <it>de novo </it>CML group and was not significantly different from the level in the healthy group. By using different primer pairs that covered different exons, five transcript variants of <it>PPP2R5C </it>could be identified. All variants could be detected in healthy samples as well as in all the leukemia samples, and similar frequencies and distributions of <it>PPP2R5C </it>were indicated.</p> <p>Conclusions</p> <p>Overexpression of <it>PPP2R5C </it>in T-cell malignancy as well as in myeloid leukemia cells might relate to its proliferation and differentiation. Investigation of the effect of target inhibition of this gene might be beneficial to further characterization of molecular mechanisms and targeted therapy in leukemia.</p
Computer–Aided Simulation of Mastoidectomy
AbstractObjectiveTo establish a three–dimensional model of the temporal bone using CT scan images for study of temporal bone structures and simulation of mastoidectomy procedures.MethodsCT scan images from 6 individuals (12 temporal bones) were used to reconstruct the Fallopian canal, internal auditory canal, cochlea, semicircular canals, sigmoid sinus, posterior fossa floor and jugular bulb on a computer platform. Their anatomical relations within the temporal bone were restored in the computed model. The same model was used to simulate mastoidectomy procedures.ResultsThe reconstructed computer model provided accurate and clear three–dimensional images of temporal bone structures. Simulation of mastoidectomy using these images provided procedural experiences closely mimicking the real surgical procedure.ConclusionComputer–aided three dimensional reconstruction of temporal bone structures using CT scan images is a useful tool in surgical simulation and can aid surgical procedure planning. Key words three–dimension reconstruction, CT scan, surgery simulatio
Effect of Pre-dispersing Metakaolin in Water on the Properties, Hydration, and Metakaolin Distribution in Mortar
The effects of pre-dispersing metakaolin (MK) in water on the properties and hydration of mortar and distribution of MK particles in mortar were characterized by analytical techniques. Zeta-potential of MK-water dispersion significantly decreased with the increase of pH of solution, resulting in a stable dispersion at pH of 8 with zeta-potential of −40 mV. The bulk density of MK-water slurry rapidly increased with water/MK ratio due to the surface tension force of water and filling of spaces by water, resulting in a maximum bulk density of 665.2 kg/m3 at water/MK ratio of 1.0. Comparing to that of powder MK, pre-dispersing MK in water did not alter hydration products, slightly improved compressive strength, and pore structure, but further reduced shrinkage and significantly improved the uniformed distribution of MK particles in mortar
The role of the peripheral system dysfunction in the pathogenesis of sepsis-associated encephalopathy
Sepsis is a condition that greatly impacts the brain, leading to neurological dysfunction and heightened mortality rates, making it one of the primary organs affected. Injury to the central nervous system can be attributed to dysfunction of various organs throughout the entire body and imbalances within the peripheral immune system. Furthermore, central nervous system injury can create a vicious circle with infection-induced peripheral immune disorders. We collate the pathogenesis of septic encephalopathy, which involves microglial activation, programmed cell death, mitochondrial dysfunction, endoplasmic reticulum stress, neurotransmitter imbalance, and blood–brain barrier disruption. We also spotlight the effects of intestinal flora and its metabolites, enterocyte-derived exosomes, cholinergic anti-inflammatory pathway, peripheral T cells and their cytokines on septic encephalopathy
Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia
<p>Abstract</p> <p>Background</p> <p>In a human T-cell acute lymphoblastic leukemia (T-ALL) cell line (Molt-4), siRNA-mediated suppression of <it>BCL11B </it>expression was shown to inhibit proliferation and induce apoptosis, functions which may be related to genes involved in apoptosis (such as <it>TNFSF10 </it>and <it>BCL2L1</it>) and TGF-β pathways (such as <it>SPP1</it>and <it>CREBBP</it>).</p> <p>Methods</p> <p>The expression levels of the above mentioned genes and their correlation with the <it>BCL11B </it>gene were analyzed in patients with T-ALL using the TaqMan and SYBR Green I real-time polymerase chain reaction technique.</p> <p>Results</p> <p>Expression levels of <it>BCL11B, BCL2L1</it>, and <it>CREBBP </it>mRNA in T-ALL patients were significantly higher than those from healthy controls (<it>P <</it>0.05). In T-ALL patients, the <it>BCL11B </it>expression level was negatively correlated with the <it>BCL2L1 </it>expression level (<it>r</it><sub>s </sub>= -0.700; <it>P </it><it><</it>0.05), and positively correlated with the <it>SPP1 </it>expression level (<it>r</it><sub>s </sub>= 0.683; <it>P </it><it><</it>0.05). In healthy controls, the <it>BCL11B </it>expression level did not correlate with the <it>TNFSF10</it>, <it>BCL2L1</it>, <it>SPP1</it>, or <it>CREBBP </it>expression levels.</p> <p>Conclusions</p> <p>Over-expression of <it>BCL11B </it>might play a role in anti-apoptosis in T-ALL cells through up-regulation of its downstream genes <it>BCL2L1 </it>and <it>CREBBP</it>.</p
Can Programming Languages Boost Each Other via Instruction Tuning?
When human programmers have mastered a programming language, it would be
easier when they learn a new programming language. In this report, we focus on
exploring whether programming languages can boost each other during the
instruction fine-tuning phase of code large language models. We conduct
extensive experiments of 8 popular programming languages (Python, JavaScript,
TypeScript, C, C++, Java, Go, HTML) on StarCoder. Results demonstrate that
programming languages can significantly improve each other. For example,
CodeM-Python 15B trained on Python is able to increase Java by an absolute
17.95% pass@1 on HumanEval-X. More surprisingly, we found that CodeM-HTML 7B
trained on the HTML corpus can improve Java by an absolute 15.24% pass@1. Our
training data is released at https://github.com/NL2Code/CodeM.Comment: Work in progres
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