A Case of Cervical Ectopic Pregnancy: Management and Review of the Literature

Introduction: Cervical ectopic pregnancy is a rare type of ectopic pregnancy. It can be diagnosed by transvaginal ultrasonography at an early stage and confirmed by magnetic resonance imaging.Presentation of case:  In such cases, early diagnosis and management can avert life-threatening consequences like uterine rupture and abundant hemorrhage, while sparing fertility. We herein discussed diagnostic process, follow-up, and management of a cervical ectopic pregnancy case.Conclusion: Cervical ectopic pregnancy has been shown that the conservative methods are safe and reliable treatment techniques in early detected cervical ectopic pregnancy cases; they also have the advantage to spare future fertility of patients

Alobar holoprosencephaly, proboscis and cyclopia in a chromosomally normal fetus: Prenatal diagnosis and fetal outcome

Holoprosencephaly is a brain malformation that develops as a result of a defect in development of prosencephalon during early gestation. Holoprosencephaly can be diagnosed with prenatal ultrasonography and magnetic resonance imaging. We report herein a case with cyclopia and holoprosencephaly detected by prenatal ultrasonography

Endometriosis localized to urinary bladder wall mimicking urinary bladder carcinoma

Although endometriosis is a common disease in women of reproductive age, urinary system endometriosis is an exceedingly rare disease that may cause important clinical problems. In this paper we discussed a 42-year-old woman who had urinary bladder endometriosis misdiagnosed as urinary bladder tumor in imaging modalities. The diagnosis of endometriosis was made by histopathological examination of the operative material after partial resection of the urinary bladder. Urinary bladder endometriosis causes nonspecific signs and symptoms in many patients. In female patients presenting with unexplained urinary symptoms the differential diagnosis should include urinary bladder endometriosis that may mimic urinary bladder cancer and lead to difficulties in making definitive preoperative diagnosis

Relationship Between Serum Fetuin-A Levels and Carotid Intima-media Thickness in Turkish Patients with Mild to Moderate Psoriasis. A Case-control Study

Previous studies have associated severe psoriasis and psoriatic arthritis with an increased risk of atherosclerosis. However, the association between patients with mild-to-moderate plaque-type psoriasis and atherosclerosis has yet to be studied in depth. This study investigates a) possible correlations between carotid intima-media thickness (CIMT) and serum fetuin-A levels in patients with mild-to-moderate psoriasis and b) correlations between psoriasis severity index (PASI) and fetuin-A levels. The latter correlation was recently reported to be important for wound healing and vascular calcification. In this prospective study, a total of 70 patients with mild-to-moderate psoriasis and 66 control participants were included. PASI, CIMT, and serum fetuin-A levels were examined in all patients. Although the difference in fetuin-A values was not statistically significant between patients with mild-to-moderate plaque-type psoriasis and control groups (P=0.401), the CIMT levels in the psoriasis group were significantly higher than the control group (P=0.002). There were no correlations among fetuin-A levels, CIMT, and PASI. This study establishes an association between mild to moderate psoriasis and atherosclerosis. This study also concludes that, similarly to patients with severe psoriasis, CIMT levels are a better indicator of cardiovascular risk than serum fetuin-A levels in patients diagnosed with mild-to-moderate plaque-type psoriasis. </p

Assessment of the coronary venous system by using cardiac CT

PURPOSEWe aimed to investigate the coronary venous system and its variations by using dual source computed tomography (CT).MATERIALS AND METHODSRetrospective assessment was carried out on 339 patients who underwent coronary CT angiography using 128-slice dual source CT for suspected coronary artery disease. The examinations were performed according to routine imaging protocols used to evaluate coronary arteries. The coronary venous system was evaluated in each case using maximum intensity projection and volume rendering technique multiplanar reformation reconstructions. In each patient, the presence and calibration of normal anatomy, as well as the variations of the coronary sinus, middle cardiac vein, small cardiac vein, posterior cardiac vein, great cardiac vein, anterior interventricular vein, posterolateral vein, left marginal vein, and anterolateral vein were recorded.RESULTSThe coronary sinus, middle cardiac vein, great cardiac vein, and anterior interventricular vein were visualized in all of the patients. In all cases, one of the lateral or posterolateral veins of appropriate localization and diameter for cardiac resynchronization therapy was detected. The posterior cardiac vein was visualized in 87% of the cases, the left marginal vein in 87.9%, and the small cardiac vein in 20%. There was no significant difference in the diameters or visibilities of the coronary veins in terms of age.CONCLUSIONThe coronary venous system and its tributaries may be examined in detail using CT angiography examination performed according to the routine coronary CT angiography protocol used for dual source CT. Dual source CT may be a valuable tool for evaluation of the coronary veins prior to invasive procedures that are directed at the coronary venous system

Kan transfüzyonu uygulanan hemofili hastası olmayan çocuklarda akkiz inhibitör gelişme sıklığı

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.ÖZET: Hemofili hastalarında inhibitor gelişmesi özellikle ağır hastalarda yaklaşık %20 oranında görülen ciddi bir tedavi komplikasyonudur. Hemofili hastası olmayan populasyonda ise akkiz anti- faktör antikor gelişimi oldukça nadirdir. Bununla beraber akkiz hemofili olarak adlandırılan bu tabloda hayati tehtid eden çok ciddi kanama ataklarının görülmesi erken tanı ve tedavinin sağlanması açısından önem taşımaktadır. Akkiz hemofili gelişimi her hangi bir kan ürünü ile temas etmeyen sağlıklı kişilerde, çeşitli oto-immun hastalıklar zemininde ve kanserli hastalarda gelişebilmektedir. Bu çalışmanın amacı değişik tipte kan ürünü ile karşılaşan beta talasemi major tanılı 51 ve pediatrik tümörlü 55 hastada akkiz faktör VIII veya IX antikoru gelişme sıklığının araştırılmasıdır. Talasemili çocuklara çalışma anına kadar ortalama 127±71 ünite (7-311) eritrosit süspansiyonu transfüzyonu yapılmıştı. Tümörlü çocukların ise 42'sine 1-11(3+2) ünite eritrosit süspansiyonu uygulanmıştı. Elde edilen sonuçlar hemofili tanısıyla izlenen 80 hasta ile herhangi bir kan ürünü ile karşılaşmayan 64 sağlıklı çocukta elde edilen sonuçlarla karşılaştırıldı. Sonuçta hemofili A tanılı hastalarda genelde %13, ağır hemofili A tanılı grupta % 22 oranda inhibitor gelişim sıklığı saptanırken, hemofili B tanılı hiçbir olguda saptanmadı. Sağlıklı çocukların ve talasemili çocukların yer aldığı gruplarda hiçbir olguda akkiz faktör VIII veya IX antikoru saptanmadı. Sadece pediatrik tümörlü hasta grubundan Osteosarkom tanısıyla tedavisi süren 14 yaşında bir kız çocuğunda 4 Bethesda ünitesi/ml titrajda inhibitor saptandı. Söz konusu inhibitor 4 aylık bir izlem sonunda kayboldu. Hastanın kanser tedavisi nedeniyle aldığı sitotoksik ilaçların (metotreksat, sisplatin ve adriablastin) antikor supresyonunda önemli rol oynadığı düşünüldü. Olguya inhibitor saptanana kadar 1 ünite trombosit süspansiyonu ve 2 Ünite eritrosit süspansiyonu transfüze edilmişti. Hastada deride ekimozlar dışında ciddi bir kanama tablosu izlenmedi. Sonuç olarak; hemofili hastası olmayan çocuklarda da tıpkı erişkinlerde olduğu gibi akkiz inhibitor gelişme riski mevcuttur. Risk oranı düşük olmakla birlikte umulmadık bir zamanda çıkabilecek hayati tehdit eden kanamaların erken tanı ve tedavisinde böyle bir tablonun ayırıcı tanıda dikkate alınması hastanın prognozu açısından önem kazanmaktadı