The Biblical View of the Sexual Polarity

The Bible contains a vast amount of information on the topic of sexuality. We can come to grips with its significant features by concentrating on the two great breakthroughs” which have resulted in the distinctly Biblical views that believers have expressed about the sexual polarity of male and female. Such an approach calls for consideration, first, of that decisive turning point in Old Testament times when Yahwism demythed the sexual realm and set up what one might call a creaturely or a creation view of the polarity of male and female. Second, we must consider the breakthrough which occurred at the dawn of New Testament times, when the polarity of male and female was viewed from a specifically Christian perspective

Mutant hepatitis B virus surface antigens (HBsAg) are immunogenic but may have a changed specificity

AbstractMutant hepatitis B virus with substitutions within the coding region for HBV surface antigen (HBsAg) has been found naturally in chronic carriers. It is therefore important to clarify whether the identified substitutions within the HBsAg have impact on the antigenicity and immunogenicity of HBsAg. A total of nine mutated HBV s-genes with single representative mutations were generated by site-directed mutagenesis and subcloned into an expression vector. The binding of polyclonal and monoclonal antibodies to these mutant HBsAg (mtHBsAg) was tested by immunofluorescence (IF) staining of cells transfected with the expression vectors. The amino acid (aa) substitutions like G145R, F134S, and C147W affected the binding of anti-HBs antibodies to corresponding mtHBsAg to different extents. The impact of aa substitutions G145R and F134S on the immunogenicity was accessed by genetic immunization of mice with vectors expressing middle HBsAg with the corresponding mutations. The immunized mice developed antibodies to recombinant HBsAg containing the HBV preS region and HBsAg-specific cytotoxic T-cell. However, the development of antibody response to wild-type small HBsAg was significantly impaired by the aa substitutions in HBsAg. Based on this fact, we further investigated whether the mtHBsAg with the aa substitution G145R is able to induce mutant-specific antibody responses. Strikingly, serum samples from mice immunized with mtHBsAg with G145R recognized plasma-derived mtHBsAg. Two mouse MAbs specific to mtHBsAg were generated. One MAb recognized mtHBsAg with G145R but not wild type and other mtHBsAg. We conclude that HBsAg with aa substitutions are immunogenic but may have a changed fine specificity

Elternspuren: Autobiographische Versuche über das NS-Trauma

Beitrag zur Friedens- und Konfliktforschung im Jahrbuch der Osnabrücker Friedensgespräche 199

Genesis Three in the Light of Key Hermeneutical Considerations

Though the Greek word έϱμηνεύειν has three main shadings (to state, to expound, and to translate) , the basic idea underlying all three meanings is to mediate understanding

The Hymn of the Week Plan

A recent development in the field of church music has been the appearance, or better, the reappearance, of the hymn-of-the-week plan, that is, the plan whereby each Sunday or festival has its own particular hymn. Such a hymn is sometimes called the de tempore hymn, that is, a hymn that fits the time, the general season and the specific day of the church year. Such a hymn is also sometimes called the Gradual hymn because the historic place for the chief hymn in the service is between Epistle and Gospel where the Gradual is sung. And such a hymn may also be called the hymn of the week

Homiletics

Homiletics and Sermon study of Ezekiel 36:22-2

Homiletics

Homiletic