Peste porcine africaine Isolement et identification en France métropolitaine. Données épidémiologiques, cliniques, anatomopathologiques et de laboratoire

Gayot Georges, Carnero R., Costes Colette, Plateau F., Delclos G., Cazaubon P. Peste porcine africaine. In: Bulletin de l'Académie Vétérinaire de France tome 127 n°2, 1974. pp. 91-97

Hog Cholera. Epidemiological study of the disease in France during the last years

L'analyse des données épidémiologiques concernant l'évolution de la peste porcine classique en France au cours des dernières années, bien que difficile pour des raisons qui sont précisées, montre une diminution de l’incidence. Si cette régression n’est pas perturbée par des événements imprévisibles et si elle est maintenue voire accélérée par les nouvelles mesures de police sanitaire il est possible d’envisager avec un optimisme prudent le succès de la campagne d’éradication qui s'inscrit dans un enga gement communautaire.Summary The analysis of the epidemiological data of the evolution of Hog Cholera during the last years in France, though it is difficult for reasons which are specified show a decrease of the incidence. If the drop is not perturbed by unforeseeable reasons and if it can be kept or even accelerated by the new sanitary measures the success of the eradication campaign can be envisaged with a prudent optimism

First isolation in France of the swine Influenza virus (Hsw1N1) during a pathological episod in a holding

Au cours d’un épisode pathologique ayant sévi dans une exploitation de porcs, il a pu être isole, pour la première fois en France, un virus influenza du porc HswiNi, accompagné d'une flore microbienne pathogène. Le virus ne s est pas transmis à l'homme et l’origine du contage est restée inconnue.Swine Influenza virus HswjNj was isolated for the first time in France during a pathological episod in a holding. The virus was not transmitted to man and the origin of contagion remained unknown

Optimization of the Inclusion of Alzheimer's Disease Patients in International Multicenter Randomized Trials: Results of a National Survey Conducted in Memory Research Centers in France

Introduction: Since 2002, with the creation of Centers of Memory Resources and Research (CMRR), considerable progress has been made in France regarding the administrative and institutional framework within which Alzheimer's disease (AD) is managed. In this study, we explore three approaches that can help optimize the inclusion of patients in clinical trials related to AD. They are as follows: to assess communication concerning clinical trials on AD in French CMRR, to analyze the internal organization of these centers concerning the dynamics of inclusion, and to evaluate screening tools used. Methods: A national, descriptive, cross-sectional survey was conducted in all CMRR in France between May 1 and July 31, 2011, using a self-administered questionnaire. All investigators, subinvestigators and the relevant CMRR personnel were involved. Results: A total of 75% of the CMRR participated, and about 30% of the physicians contacted responded positively to the survey. Only 50% reported having communicated with health care professionals at least once in the previous 3 months, and less than 50% had communicated occasionally with the general public. A total of 75% of those surveyed had a research group but only half of the groups were active, 50% of the physicians did not have a consultation time dedicated to study recruitment, and 75% of the respondents had a screening tool in their CMRR but over half of them were not satisfied with it. Conclusion: This investigation provides a basis for improving the screening of patients by both internal organizational development and adaptation of tools already available. Improvement requires promoting regular communication that is appropriate and targeted to health care professionals, smaller memory centers, associations and the public, and therefore, familiarizing the whole population with clinical research on AD

Premier isolement en France du virus de l'influenza du porc (Hsw1N1) dans un environnement pathologique plurimicrobien

Swine Influenza virus Hsw1N1 was isolated for the first time in France during a pathological episod in a holding. The virus was not transmitted to man and the origin of contagion remained unknown.Au cours d'un épisode pathologique ayant sévi dans une exploitation de porcs, il a pu être isolé, pour la première fois en France, un virus influenza du porc Hsw1N1, accompagné d'une flore microbienne pathogène. Le virus ne s'est pas transmis à l'homme et l’origine du contage est restée inconnue.Gourreau Jean-Marie, Kaiser C., Hannoun Claude, Vaissaire Josée, Gayot G., Gicquel B., Labie C., Mirial Ginette. Premier isolement en France du virus de l'influenza du porc (Hsw1N1) dans un environnement pathologique plurimicrobien. In: Bulletin de l'Académie Vétérinaire de France tome 133 n°1, 1980. pp. 181-188

Structure-Function Relationship of Iron Oxide Nanoflowers: Optimal Sizes for Magnetic Hyperthermia Depending on Alternating Magnetic Field Conditions

Iron oxide nanoflowers (IONFs) that display singular magnetic properties can be synthesized through a polyol route first introduced almost 2 decades ago by Caruntu et al, presenting a multi-core morphology in which several grains (around 10 nm) are attached together and sintered. These outstanding properties are of great interest for magnetic field hyperthermia, which is considered as a promising therapy against cancer. Although of significantly smaller diameter, the specific adsorption rate (SAR) of IONFs reach values on the order of 1 kW·g-1, as large as “magnetosomes” that are natural magnetic nanoparticles typically ∼40 nm found in certain bacteria, which can be grown artificially but with much lower yield compared to chemical synthesis such as the polyol route. This work aims at better understanding the structure-property relationships, linking the internal IONF nanostructure as observed by high resolution transmission electron microscopy (HR-TEM) to their magnetic properties. A library of mono- and multicore IONFs is presented, with diameters ranging from 11 to 30 nm in a narrow size distribution. More particularly, by relating their structural features (diameter, morphology, defects…) to their magnetic properties investigated by utilizing AC magnetometry over a wide range of alternating magnetic field (AMF) conditions, we showed that the SAR values of all synthesized batches vary with overall diameter and number of constituting cores. These variations are in qualitative agreement with theoretical predictions either by the Linear Response Theory (LRT) at low fields or with the Stoner-Wohlfarth (SW) model at larger amplitudes, and with numerical simulations reported previously. More precisely, our results show a continuous (almost quadratic) increase of SAR with IONF diameter for AMF amplitudes of 20 kA·m-1 and above, whatever the frequency between 146 and 344 kHz, and a pronounced maximum at an IONF diameter of 22 nm for amplitudes of 16 kA·m-1 and below. Thank to this understanding of the impact of size and core multiplicity, stable colloidal solutions of IONPs can be synthesized with diameters targeting a SAR value adapted to the theragnostic approach envisioned.Mortalité Cellulaire Induite par Rotation de VEsicules MagnétiquesModifications chimiques de la surface interne de NPs PEGylées pour orienter l'identité biologique de la protein corona vers des macrophages de la plaque d'athérom

A designed organic-zeolite hybrid acid-base catalyst

An organic–zeolite hybrid catalyst was synthesised via solid-state impregnation of the zeolite with an amount of melamine corresponding to 20 mol% of the aluminium content. A high density of basic sites is formed in the zeolite. From infrared spectroscopy and TGA measurements we infer that melaminium cations are formed in the zeolite which are highly thermally stable. IR spectroscopic and TGA measurements showed the presence of melaminium after pre-treatment in vacuum at 450°C. The catalyst exhibited activity in the Knoevenagel condensation reaction between benzaldehyde and ethyl cyanoacetate which is suggested to be promoted by the presence of acid and base sites. The catalyst activity was compared with other known base catalysts including hydrotalcites and magnesium oxide on alumina support

Efficacité d'une eau gélifiée et d'une poudre épaississante destinées aux patients dysphagiques aux liquides.

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