32 research outputs found
Sport and type 1 diabetes mellitus
Sportowcy chorzy na cukrzycę wymagają indywidualnej
edukacji i dostosowania modelu leczenia do
wymagań sportowych. Dobre wyrównanie metaboliczne
cukrzycy stanowi kluczowy element efektywności
treningu fizycznego i sukcesu sportowego. Błędy
w zakresie insulinoterapii nie tylko negatywnie
wpływają na osiągnięcia sportowe, ale, co ważniejsze,
zwiększają ryzyko wystąpienia ostrych powikłań
cukrzycy, hipoglikemii i kwasicy cukrzycowej ketonowej.
(Diabet. Prakt. 2011; 12, 2: 52–55)Athletes with diabetes call for individual diabetic
education and their insulin treatment should be adapted
to sporty demand. Good metabolic control of
diabetes is a key element of physical training efficiency.
Misstatements in insulin treatment have negative
effect on athletic accomplishments and increase
the risk of acute diabetic complications such as
hypoglycemia and diabetic ketoacidosis. (Diabet.
Prakt. 2011; 12, 2: 52–55
Selected aspects of insulin pump theraphy in adults with type 1 diabetes
Cukrzyca typu 1 jest chorobą spowodowaną bezwzględnym
niedoborem insuliny. Rozpoznaje się ją
u coraz większej liczby dzieci, młodzieży oraz młodych
dorosłych. Leczeniem z wyboru jest metoda intensywnej
czynnościowej insulinoterapii. U większości
pacjentów jest ona realizowana za pomocą
wstrzykiwaczy typu pen. W ostatnich latach wzrasta
jednak liczba pacjentów leczonych za pomocą osobistej
pompy insulinowej. Terapia ta wymaga odpowiedniego
przygotowania nie tylko ze strony pacjenta,
ale również zespołu leczącego. (Diabet. Prakt.
2011, tom 12, nr 4, 128–133)Type 1 diabetes is a disease caused by absolute insulin
deficiency. Cases are found in a growing number of
children, adolescents and young adults. Treatment
of choice for type 1 diabetes is a method of intensive
functional insulin therapy. In most patients it is
implemented using pens. However, in recent years
an increasing number of patients treated with
a personal insulin pump. This therapy requires
adequate preparation by the patient, but also the
treatment team. (Diabet. Prakt. 2011, vol. 12, no 4,
128–133
Assessment of glycaemia increment after protein-fat containing meal in type 1 diabetic patients treated with continous subcutaneous insulin infusion
WSTĘP. Glikemia poposiłkowa stanowi istotny element
kontroli cukrzycy. Celem badania była ocena
wpływu posiłku białkowo-tłuszczowego na glikemię
u chorych na cukrzycę typu 1 leczonych za pomocą
osobistej pompy insulinowej, w zależności od iniekcji
bolusa insuliny przed posiłkiem.
MATERIAŁ I METODY. Badaniem objęto 30 chorych
na cukrzycę typu 1 w wieku 18-50 lat (26,3 ± 7,1
roku), ze średnim czasem trwania cukrzycy 12,3 ±
6,4 roku, leczonych za pomocą osobistej pompy
insulinowej. Wszyscy badani spożyli wystandaryzowany
posiłek składający się z 7 wymienników białkowo-tłuszczowych (WBT) i oznaczali glikemię co 30 minut
przez 8 godzin. Piętnaście wybranych losowo
osób (grupa interwencyjna) przyjęło przed posiłkiem
insulinę (3,5 jednostki insuliny) w formie bolusa
przedłużonego na 8 godzin, a kolejnych 15 (grupa
kontrolna) - nie zastosowało bolusa insuliny. WYNIKI. Glikemia w grupie interwencyjnej była znamiennie
mniejsza niż w grupie kontrolnej w 180.,
330., 420., 450. i 480. minucie. Na podstawie analizy
zmian wartości glikemii w poszczególnych grupach
stwierdzono istotny statystycznie wzrost glikemii
między 90. a 420. minutą testu w grupie kontrolnej,
ale nie w interwencyjnej (p < 0,05).
WNIOSKI. Spożywanie białka i tłuszczu wymaga dodatkowej
dawki insuliny w formie bolusa przedłużonego.
Ilość insuliny bilansująca 1 WBT powinna być
przynajmniej o połowę mniejsza niż w przypadku
wymiennika węglowodanowego. Czas bolusa przedłużonego
po spożyciu 7 WBT powinien być krótszy
niż 8 godzin. (Diabet. Prakt. 2010; 11, 1: 9-16)BACKGROUND. Postprandial glycaemia is an important
component of metabolic control in diabetics. The goal
of this study was to evaluate the influence of fatprotein
containing meal on glycaemia in type 1
diabetic patients treated with continous subcutaneous
insulin infusion pump who were given square
insulin bolus before meal.
MATERIAL AND METHODS. Thirtieth type 1 diabetic
patients aged 18-50 years (26.3 ± 7.1), with the mean duration of the disease 12.3 ± 6.4 years, using
continous subcutaneous insulin infusion pump were
included in this study. All patients received the
standardised meal containing 7 protein-fat exchanges
and had blood glucose levels checked every 30 minutes
during 8 hours period. Patients were randomized into
2 groups: 15 patients of the investigated group gave
square insulin bolus (3.5 insulin units) before meal, 15
of the control group did not.
RESULTS. The glycaemia in the investigated group
was significantly lower then in the control group in
180, 330, 420, 450 and 480 minute. The analysis of
the glycaemia in both groups revealed statistically
significant increase of blood glucose between 90 and
420 minute in the control group, but not in the
investigated group (p < 0.05).
CONCLUSIONS. Protein and fat intake necessitates
additional dose of insulin given as square bolus. The
insulin dose for 1 protein-fat exchange should be
lowered at least by half when compared with
carbohydrate/insulin ratio. The duration of square insulin
bolus given for 7 protein-fat exchanges should be shorter
than 8 hours. (Diabet. Prakt. 2010; 11, 1: 9-16
Selected aspects of insulin pump theraphy in adults with type 1 diabetes
Cukrzyca typu 1 jest chorobą spowodowaną bezwzględnym niedoborem insuliny. Rozpoznaje
się ją u coraz większej liczby dzieci, młodzieży oraz młodych dorosłych. Leczeniem
z wyboru jest metoda intensywnej czynnościowej insulinoterapii. U większości pacjentów jest
ona realizowana za pomocą wstrzykiwaczy typu pen. W ostatnich latach wzrasta jednak
liczba pacjentów leczonych za pomocą osobistej pompy insulinowej. Terapia ta wymaga
odpowiedniego przygotowania nie tylko ze strony pacjenta, ale również zespołu leczącego.
(Forum Zaburzeń Metabolicznych 2011, tom 2, nr 2, 143–150)Type 1 diabetes is a disease caused by absolute insulin deficiency. Cases are found in
a growing number of children, adolescents and young adults. Treatment of choice for type 1
diabetes is a method of intensive functional insulin therapy. In most patients it is implemented
using pens. However, in recent years an increasing number of patients treated with
a personal insulin pump. This therapy requires adequate preparation by the patient, but also
the treatment team. (Forum Zaburzen Metabolicznych 2011, vol. 2, no 2, 143–150
The association between the level of baseline daily physical activity and selected clinical and biochemical parameters during mountain trekking in patients with type 1 diabetes
Introduction. There is a general agreement that regular physical activity should be recommended for patients with type 1 diabetes mellitus (T1DM), as it positively affects blood pressure and lipid levels and diminishes the risk of T1DM complications. Aim of this study was to search for a correlation between lactate level, degree of fatigue, and patient-reported physical activity in T1DM patients while trekking up to 3000 meters above sea level (masl).
Material and methods. Study group consisted of 19 participants (2 women) in mean age of 31 years with T1DM who summited 3000 masl in Alps. Clinical information was taken from patient questionnaire, personal insulin pumps and blood analysis (glucose, lactate level). Additionally patient self-assessment of physical activity and fatigue (Borg scale) was used.
Results. Declared physical activity in the last six months correlated with the initial, second, and final ratings of fatigue according to the Borg Scale during the expedition day, p = 0.02, r = –0.65; p = 0.02, r = –0.54; p = 0.01, r = –0.61, respectively. Blood lactate levels tended to increase with duration of exercise and altitude. Also, the average level of lactate on the expedition correlated with the average level of fatigue (p = 0.02, r = 0.57).
Conclusion. Before undertaking day-long mountain trekking, T1DM patients with a sedentary lifestyle should improve their fitness. The measurement of lactate levels can be a useful tool to predict fatigue as measured with the Borg Scale. (Clin Diabetol 2017; 6, 3: 77–80)Introduction. There is a general agreement that regular physical activity should be recommended for patients with type 1 diabetes mellitus (T1DM), as it positively affects blood pressure and lipid levels and diminishes the risk of T1DM complications. Aim of this study was to search for a correlation between lactate level, degree of fatigue, and patient-reported physical activity in T1DM patients while trekking up to 3000 meters above sea level (masl).
Material and methods. Study group consisted of 19 participants (2 women) in mean age of 31 years with T1DM who summited 3000 masl in Alps. Clinical information was taken from patient questionnaire, personal insulin pumps and blood analysis (glucose, lactate level). Additionally patient self-assessment of physical activity and fatigue (Borg scale) was used.
Results. Declared physical activity in the last six months correlated with the initial, second, and final ratings of fatigue according to the Borg Scale during the expedition day, p = 0.02, r = –0.65; p = 0.02, r = –0.54; p = 0.01, r = –0.61, respectively. Blood lactate levels tended to increase with duration of exercise and altitude. Also, the average level of lactate on the expedition correlated with the average level of fatigue (p = 0.02, r = 0.57).
Conclusion. Before undertaking day-long mountain trekking, T1DM patients with a sedentary lifestyle should improve their fitness. The measurement of lactate levels can be a useful tool to predict fatigue as measured with the Borg Scale. (Clin Diabetol 2017; 6, 3: 77–80
Physiological characteristics of type 1 diabetes patients during high mountain trekking
In this study, the aim was to provide observational data from an ascent to the summit of Mount Damavand (5670 meters above sea level (m.a.s.l), Iran) by a group of people with type 1 diabetes (T1DM), with a focus on their physiological characteristics. After a 3-day expedition, 18 T1DM patients, all treated with personal insulin pumps, successfully climbed Mount Damavand. Information was collected on their physiological and dietary behaviors, as well as medical parameters, such as carbohydrate consumption, glucose patterns, insulin dosing, and the number of hypo- and hyperglycemic episodes during this time frame. The participants consumed significantly less carbohydrates on day 3 compared to day 1 (16.4 vs. 23.1 carbohydrate units; p=0.037). Despite this, a gradual rise in the mean daily glucose concentration as measured with a glucometer was observed. Interestingly, the patients did not fully respond to higher insulin delivery as there was no significant difference in mean daily insulin dose during the expedition. There were more hyperglycemic episodes (≥180 mg/dL) per patient on day 3 vs. day 1 (p250 mg/dL) per patient on days 2 (p<0.05) and 3 (p<0.05) vs. day 1. In summary, high mountain trekking is feasible for T1DM patients with good glycemic control and no chronic complications. However, some changes in dietary preferences and an observable rise in glucose levels may occur. This requires an adequate therapeutic response