2,921 research outputs found
Casimir interaction at liquid nitrogen temperature: Comparison between experiment and theory
We have measured the normalized gradient of the Casimir force between
Au-coated surfaces of the sphere and the plate and equivalent Casimir pressure
between two parallel Au plates at T=77K. These measurements have been performed
by means of dynamic force microscope adapted for operating at low temperatures
in the frequency shift technique. It was shown that the measurement results at
T=77K are in a very good agreement with those at T=300K and with computations
at T=77K using both theoretical approaches to the thermal Casimir force
proposed in the literature. No thermal effect in the Casimir pressure was
observed in the limit of experimental errors with the increase of temperature
from T=77K to T=300K. Taking this into account, we have discussed the possible
role of patch potentials in the comparison between measured and calculated
Casimir pressures.Comment: 18 pages, 8 figures, to appear in Phys. Rev.
Brief communication: Significant biases in ERA5 output for the McMurdo Dry Valleys region, Antarctica
The ERA5 climate reanalysis dataset plays an important role in applications such as monitoring and modeling climate system changes in polar regions, so the calibration of the reanalysis to ground observations is of great relevance. Here, we compare the 2 m air temperature time series of the ERA5 reanalysis and the near-surface bias-corrected reanalysis to the near-ground air temperature measured at 17 automatic weather stations (AWSs) in the McMurdo Dry Valleys, Antarctica. We find that the reanalysis data have biases that change with the season of the year and do not clearly correlate with elevation. Our results show that future work should rely on secondary observations to calibrate when using the ERA5 reanalysis in polar regions.</p
The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast.
Sgf73, a core component of SAGA, is the yeast orthologue of ataxin-7, which undergoes CAG-polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (SCA7). Deletion of SGF73 dramatically extends replicative lifespan (RLS) in yeast. To further define the basis for Sgf73-mediated RLS extension, we performed ChIP-Seq, identified 388 unique genomic regions occupied by Sgf73, and noted enrichment in promoters of ribosomal protein (RP)-encoding genes. Of 388 Sgf73 binding sites, 33 correspond to 5' regions of genes implicated in RLS extension, including 20 genes encoding RPs. Furthermore, half of Sgf73-occupied, RLS-linked RP genes displayed significantly reduced expression in sgf73Δ mutants, and double null strains lacking SGF73 and a Sgf73-regulated, RLS-linked RP gene exhibited no further increase in replicative lifespan. We also found that sgf73Δ mutants display altered acetylation of Ifh1, an important regulator of RP gene transcription. These findings implicate altered ribosomal protein expression in sgf73Δ yeast RLS and highlight altered acetylation as a pathway of relevance for SCA7 neurodegeneration
Logistics service providers and Industry 4.0: A systematic literature review
Background: Industry 4.0 is one of the topics related to manufacturing, supply chain and logistics that has received great interest from the academic community, organizations and governments in the last decade. Problem statement: Several published articles discuss and seek to conceptualize what the fourth industrial revolution is, but no research relates industry 4.0 in the context of logistics service providers (LSPs) in a clear and structured way. Objectives: This study aims to fill this research gap, proposing a conceptual framework and addressing the challenges, barriers and organizational dimensions that need adaptation to insert LSPs in the new Industry 4.0 environment. Methods: This theoretical and conceptual study uses the Systematic Literature Review (SLR) as a research method to understand the Industry 4.0 phenomenon in the context of LSPs. Contributions: The relevant constructs identified in this research will help professionals and organizations that provide logistics services to develop strategies and encourage new research in the 15 field of Industry 4.0 from the perspective of LSPs. Results: In addition, this research identified and generally consolidated six dimensions, as a result of this innovative study a conceptual framework is presented
A toolset for complex decision making in analyze phase of Lean Six Sigma Project: A case validation
The analyze phase of Lean Six Sigma (LSS) project is an important phase where the project heads and organizational directors need to select the critical issues for further improvements. The present work is primarily focused on analyze phase of LSS project to prioritized the Critical to Quality (CTQs) in a particular case industry. The CTQs prioritization is being done based on the five evaluation criteria found from the literature. The weights of the criteria are determined through the Modified Digital Logic (MDL) method. The identified CTQs in assembly section of case industry have been ranked through the Grey Relation Analysis (GRA) under fuzzy environment. The results of the study have been validated using fuzzy VIKOR. It is found that the ‘cost’ criterion is the most significant among other criteria with MDL weight of 0.3. Through fuzzy-GRA, out of ten identified CTQs, non availability of rack system is found to be the most critical issue in assembly section of case industry. The perceptions of industrial manager and production head of case industry are strongly in favor of the obtained results and has implemented the suggested solutions.To sustain in the competitive environment and produce quality product at right time, organizations need to control their CTQs as per their criticality. For this, the decision making becomes quite complex to select the most critical factors due to the fascinating nature of various criteria and sub-criteria. The present study is the first attempt that has implemented the multi-criteria decision-making approach in analyze phase of LSS project
Gradient of the Casimir force between Au surfaces of a sphere and a plate measured using atomic force microscope in a frequency shift technique
We present measurement results for the gradient of the Casimir force between
an Au-coated sphere and an Au-coated plate obtained by means of an atomic force
microscope operated in a frequency shift technique. This experiment was
performed at a pressure of 3x10^{-8} Torr with hollow glass sphere of 41.3 mcm
radius. Special attention is paid to electrostatic calibrations including the
problem of electrostatic patches. All calibration parameters are shown to be
separation-independent after the corrections for mechanical drift are included.
The gradient of the Casimir force was measured in two ways with applied
compensating voltage to the plate and with different applied voltages and
subsequent subtraction of electric forces. The obtained mean gradients are
shown to be in mutual agreement and in agreement with previous experiments
performed using a micromachined oscillator. The obtained data are compared with
theoretical predictions of the Lifshitz theory including corrections beyond the
proximity force approximation. An independent comparison with no fitting
parameters demonstrated that the Drude model approach is excluded by the data
at a 67% confidence level over the separation region from 235 to 420 nm. The
theoretical approach using the generalized plasma-like model is shown to be
consistent with the data over the entire measurement range. Corrections due to
the nonlinearity of oscillator are calculated and the application region of the
linear regime is determined. A conclusion is made that the results of several
performed experiments call for a thorough analysis of the basics of the theory
of dispersion forces.Comment: 35 pages, 14 figures, 1 table; to appear in Phys. Rev.
Integration of Blockchain and Lean Six Sigma approach for operational excellence: A proposed model
Purpose
This study aims to explore the potential application of blockchain technology in Lean Six Sigma (LSS) project through a proposed blockchain-LSS (BLSS) model. The proposed model can tackle real-time problems in information sharing, transparency and traceability in every stage of the LSS project.
Design/methodology/approach
The scoping review approach is used to develop the integrated model of the BLSS approach for operational excellence. The proposed model is validated through expert’s input, which is collected by a questionnaire survey method.
Findings
The prime function of the proposed BLSS model is the information sharing among the project team and real-time monitoring, transparency, traceability and immutability in the Define-Measure-Analyze-Improve-Control phase. The proposed model also consists the information about the role of blockchain features at each phase of the LSS project. The project team and industry employees can trace the success of the project at every moment, resulting in trust buildup and the elimination of fake data. Moreover, there would be no disputes among various sections/shops of the plant and employees to share the real information.
Practical implications
This paper provides guidelines to practitioners and managers for integrating the LSS approach and blockchain. The blockchain helps managers and practitioners in better data traceability and transparency, monitoring of data as well as more sustainable LSS project management.
Originality/value
To the best of the authors’ knowledge, this is the first research attempt that developed an integrated model of blockchain and LSS approach to maintaining the immutable records of assets in projects and targeted Industry 4.0
Evaluating the impact of a longitudinal patient case on the development of professionalism and professional identity
This article explores the student outcomes of a progressive case on the development of professional identity and professionalism within first-year student pharmacists
Why do Process Improvement Projects Fail in Organizations? A Review and Future Research Agenda
Purpose: The purpose of this article is to examine the Critical Failure Factors (CFFs) linked to various
types of Process improvement (PI) projects such as Kaizen, Lean, Six Sigma, Lean Six Sigma and Agile.
Proposing a mitigation framework accordingly is also an aim of this study.
Design/ Methodology/ Approach: This research undertakes a systematic literature review of 49 articles
that were relevant to the scope of our study and that were published in four prominent databases including
Google Scholar, Scopus, Web of Science and EBSCO.
Findings: Further analysis identifies 39 factors that contribute to the failure of PI projects. Among these
factors, significant emphasis is placed on issues such as "resistance to cultural change," "insufficient
support from top management," "inadequate training and education," "poor communication," and "lack of
resources", as primary causes of PI project failures. To address and overcome the PI project failures, we
propose a framework for failure mitigation based on change management models. We present future
research directions that aim to enhance both the theoretical understanding and practical aspects of PI
project failures.
Practical Implications: Through this study researchers and project managers can benefit from well structured guidelines and invaluable insights that will help them identify and address potential failures,
leading to successful implementation and sustainable improvements within organizations.
Originality: This paper is the first study of its kind that examine the CFFs of five PI methodologies and
introduces a novel approach derived from change management theory as a solution to minimize the risk
associated with PI failure
Modifying the Casimir force between indium tin oxide film and Au sphere
We present complete results of the experiment on measuring the Casimir force
between an Au-coated sphere and an untreated or, alternatively, UV-treated
indium tin oxide film deposited on a quartz substrate. Measurements were
performed using an atomic force microscope in a high vacuum chamber. The
measurement system was calibrated electrostatically. Special analysis of the
systematic deviations is performed, and respective corrections in the
calibration parameters are introduced. The corrected parameters are free from
anomalies discussed in the literature. The experimental data for the Casimir
force from two measurement sets for both untreated and UV-treated samples are
presented. The experimental errors are determined at a 95% confidence level. It
is demonstrated that the UV treatment of an I TO plate results in a significant
decrease in the magnitude of the Casimir force (from 21% to 35% depending on
separation). However, ellipsometry measurements of the imaginary parts of
dielectric permittivities of the untreated and UV-treated samples did not
reveal any significant differences. The experimental data are compared with
computations in the framework of the Lifshitz theory. It is found that the data
for the untreated sample are in a very good agreement with theoretical results
taking into account the free charge carriers in an ITO film. For the UV-treated
sample the data exclude the theoretical results obtained with account of free
charge carriers. These data are in a very good agreement with computations
disregarding the contribution of free carriers. According to the explanation
provided, this is caused by the phase transition of the ITO film from metallic
to dielectric state caused by the UV treatment. Possible applications of the
discovered phenomenon in nanotechnology are discussed.Comment: 30 pages, 19 figures, 1 tabl
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