Annotated list of definitions for mass drug administration (MDA) programs used by the World Health Organization and the research community [84].

<p>Annotated list of definitions for mass drug administration (MDA) programs used by the World Health Organization and the research community <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0002447#pntd.0002447-WHO3" target="_blank">[84]</a>.</p

Research needs and gaps in understanding.

<p>Research needs and gaps in understanding.</p

A basic troubleshooting guide for commonly encountered problems in MDA programs.

<p>A basic troubleshooting guide for commonly encountered problems in MDA programs.</p

Major factors that affect individual compliance with mass drug administration for elimination of lymphatic filariasis.

<p>Major factors that affect individual compliance with mass drug administration for elimination of lymphatic filariasis.</p

PRISMA flow diagram for inclusion of articles in the quantitative synthesis.

<p>PRISMA flow diagram for inclusion of articles in the quantitative synthesis.</p

Inclusion and exclusion criteria for quantitative analysis.

<p>Inclusion and exclusion criteria for quantitative analysis.</p

Reported percentages of specific AEs in treatment arms with 100% microfilaremia rates (shaded bars) or no microfilaremia (open bars).

<p>Only studies with active AE reporting are included and each study arm is given equal weight (not weighted by participant number). Boxes indicate the interquartile range (IQR) and dashed line the median. Whiskers indicate the upper and lower adjacent values: upper = the greatest value less than (75th percentile + (1.5 x IQR)); lower = the lowest value greater than (25th percentile–(1.5 x IQR)).</p

Percentage of participants experiencing common systemic AEs by treatment group, according to the microfilaremia status of participants.

<p>DEC and IVM data include all study arms where the indicated drug was given alone or in combination (with or without ALB). For clarity, the ALB panel shows only study arms in which ALB alone was given. The upper panels assign each study are equal weight; the lower panels are weighted according to number of participants per study arm. Boxes indicate the interquartile range (IQR) and horizontal line the median. Whiskers indicate the upper and lower adjacent values: upper = the greatest value less than (75th percentile + (1.5 x IQR)); lower = the lowest value greater than (25th percentile–(1.5 x IQR)).</p

Articles included in the quantitative analysis by article type and study location.

<p>Articles included in the quantitative analysis by article type and study location.</p

Ultrastructural characteristics of predominant <i>Wolbachia</i> forms of <i>B. malayi</i> found in the examined parasite material.

<p>Ultrastructural characteristics of predominant <i>Wolbachia</i> forms of <i>B. malayi</i> found in the examined parasite material.</p