Heterogeneity in Longitudinal Healthcare Utilisation by Older Adults: A Latent Transition Analysis of the Irish Longitudinal Study on Ageing

BACKGROUND: Older adults likely exhibit considerable differences in healthcare need and usage. Identifying differences in healthcare utilisation both between and within individuals over time may support future service development. OBJECTIVES: To characterise temporal changes in healthcare utilisation among a nationally representative sample of community-dwelling older adults. METHODS: A latent transition analysis of the first three waves of The Irish Longitudinal Study on Ageing (TILDA) (N = 6128) was conducted. RESULTS: Three latent classes of healthcare utilisation were identified, ‘primary care only’; ‘primary care and outpatient visits’ and ‘multiple utilisation’. The classes were invariant across all three waves. Transition probabilities indicated dynamic changes over time, particularly for the ‘primary care and outpatient visits’ and ‘multiple utilisation’ statuses. DISCUSSION: Older adults exhibit temporal changes in healthcare utilisation which may reflect changes in healthcare need and disease progression. Further research is required to identify the factors which influence movement between healthcare utilisation patterns

XR & Museums: Mixing Disciplines, Extending Boundaries, and Delivering Multi-Modal Experiences in a Post-COVID World

Our talk demonstrates and elaborates upon the ways in which the development of mixed reality with museum partners can, and has, fostered the mixing of disciplines among academic faculty, thereby encouraging the breaking down of silos in the university environment

Targeting senescent cells in translational medicine.

Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest occurring in response to damage and stress and is considered a hallmark of ageing. Senescent cells accumulate in multiple organs during ageing, contribute to tissue dysfunction and give rise to pathological manifestations. Senescence is therefore a defining feature of a variety of human age-related disorders, including cancer, and targeted elimination of these cells has recently emerged as a promising therapeutic approach to ameliorate tissue damage and promote repair and regeneration. In addition, in vivo identification of senescent cells has significant potential for early diagnosis of multiple pathologies. Here, we review existing senolytics, small molecules and drug delivery tools used in preclinical therapeutic strategies involving cellular senescence, as well as probes to trace senescent cells. We also review the clinical research landscape in senescence and discuss how identifying and targeting cellular senescence might positively affect pathological and ageing processes

A Project to Foster Behavioural Monitoring in the Field of ADHD

info:eu-repo/semantics/publishedVersio

An innovative and meaningful scaffolded curriculum approach to environmental health education in Western Australia

There has been a critical shortage of qualified Environmental Health Officers (EHOs) both globally and in Australia that has plagued the profession for decades. At Edith Cowan University (ECU), Perth, Western Australia, an undergraduate degree in Environmental Health (EH) was developed in 2006, however, viability was problematic, and the course was under threat of closure. In 2016 both the EH and occupational safety and health (OSH) majors were due for re-accreditation and since there was significant overlap between the two courses both majors were revised and combined into one (Occupational and Environmental Health and Safety). This new qualification has subsequently been accredited by Environmental Health Australia (EHA), as well as the Australian OHS Education Accreditation Board (AOHSEAB) and the British Institution of Occupational Safety and Health (IOSH). The new dual accredited course has had excellent graduate outcomes and provides graduates with the flexibility to move between traditional OHS and EH roles. In some smaller local governments, and in industry, ECU graduates have been employed to work in both roles. The curriculum was developed in consultation with industry and has an embedded year-long diploma course that consists of eight units (subjects/courses) that prepare graduates to work in a support role to EHOs. The Diploma of Environmental Health course is a scaffolded course that is embedded in the degree, and it has been recognized by the State Government as a qualification leading to appointment as authorized officers under the Public Health Act 2016 (WA). The diploma is more than a pathway course as it is a stand-alone qualification that leads to gainful employment. Most students now enroll in the diploma, initially and gain employment as a Technical Officer, and then progress on to complete the EH degree on a part-time basis while employed in the profession. The diploma is also an exit option for students who struggle with the academic requirements of some of the more traditionally difficult units such as physics, chemistry, and statistics and the EH degree is now a viable university course with excellent graduate employment outcomes