Structure formation in the presence of relativistic heat conduction: corrections to the Jeans wave number with a stable first order in the gradients formalism

The problem of structure formation in relativistic dissipative fluids was analyzed in a previous work within Eckart's framework, in which the heat flux is coupled to the hydrodynamic acceleration, additional to the usual temperature gradient term. It was shown that in such case, the pathological behavior of fluctuations leads to the disapperance of the gravitational instability responsible for structure formation. In the present work the problem is revisited now using a constitutive equation derived from relativistic kinetic theory. The new relation, in which the heat flux is not coupled to the hydrodynamic acceleration, leads to a consistent first order in the gradients formalism. In this case the gravitational instability remains, and only relativistic corrections to the Jeans wave number are obtained. In the calculation here shown the non-relativistc limit is recovered, opposite to what happens in Eckart's case.Comment: 10 pages, no figure

Hyperonic crystallization in hadronic matter

Published in Hadrons, Nuclei and Applications, World Scientific, Singapore, Proc.of the Conference Bologna2000. Structure of the Nucleus at the Dawn of the Century, G. Bonsignori, M. Bruno, A. Ventura, D. Vretenar Editors, pag. 319.Comment: 4 pages, 2figure

Determinants of Infodemics During Disease Outbreaks: A Systematic Review

Background: The widespread use of social media represents an unprecedented opportunity for health promotion. We have more information and evidence-based health related knowledge, for instance about healthy habits or possible risk behaviors. However, these tools also carry some disadvantages since they also open the door to new social and health risks, in particular during health emergencies. This systematic review aims to study the determinants of infodemics during disease outbreaks, drawing on both quantitative and qualitative methods. Methods: We searched research articles in PubMed, Scopus, Medline, Embase, CINAHL, Sociological abstracts, Cochrane Library, and Web of Science. Additional research works were included by searching bibliographies of electronically retrieved review articles. Results: Finally, 42 studies were included in the review. Five determinants of infodemics were identified: (1) information sources; (2) online communities' structure and consensus; (3) communication channels (i.e., mass media, social media, forums, and websites); (4) messages content (i.e., quality of information, sensationalism, etc.,); and (5) context (e.g., social consensus, health emergencies, public opinion, etc.). Studied selected in this systematic review identified different measures to combat misinformation during outbreaks. Conclusion: The clarity of the health promotion messages has been proven essential to prevent the spread of a particular disease and to avoid potential risks, but it is also fundamental to understand the network structure of social media platforms and the emergency context where misinformation might dynamically evolve. Therefore, in order to prevent future infodemics, special attention will need to be paid both to increase the visibility of evidence-based knowledge generated by health organizations and academia, and to detect the possible sources of mis/disinformation

Enhancement of metabolite production in high-altitude microalgal strains by optimized C/N/P ratio

This study evaluated the role of C/N/P in the increase in the synthesis of carbohydrates, proteins, and lipids in two high-mountain strains of algae (Chlorella sp. UFPS019 and Desmodesmus sp. UFPS021). Three carbon sources (sodium acetate, sodium carbonate, and sodium bicarbonate), and the sources of nitrogen (NaNO3) and phosphate (KH2PO4 and K2HPO4) were analyzed using a surface response (3 factors, 2 levels). In Chlorella sp. UFPS019, the optimal conditions to enhance the synthesis of carbohydrates were high sodium carbonate content (3.53 g/L), high KH2PO4 and K2HPO4 content (0.06 and 0.14 g/L, respectively), and medium-high NaNO3 (0.1875 g/L). In the case of lipids, a high concentration of sodium acetate (1.19 g/L) coupled with high KH2PO4 and K2HPO4 content (0.056 and 0.131 g/L, respectively) and a low concentration of NaNO3 (0.075 g/L) drastically induced the synthesis of lipids. In the case of Desmodesmus sp. UFPS021, the protein content was increased using high sodium acetate (2 g/L), high KH2PO4 and K2HPO4 content (0.056 and 0.131 g/L, respectively), and high NaNO3 concentration (0.25 g/L). These results demonstrate that the correct adjustment of the C/N/P ratio can enhance the capacity of high-mountain strains of algae to produce high concentrations of carbohydrates, proteins, and lipids

The effect of temperature and enzyme concentration in the transesterification process of synthetic microalgae oil

Throughout the world, the fossil fuel has supplied around the 80% of the energetic requirements, in Colombia alone 95.1% of energetic demand is made by the transportation sector solely, supplied by oil, kerosene, gasoline and diesel, this sector has an extremely small participation with biofuel of 3%, which is represented only by biodiesel. Microalgae had been proposed as biofactories with a remarkable third generation biofuels production. The culture of the microorganism comprehends interesting characteristics as countless environments where its natural growth could be replicated in fresh, salty and even sewage waters, with a higher growth rate and a higher oil production. The implementation of enzymes in the transesterification process have generated a good curiosity in the field, due to its mild reactions conditions, lesser energetic requirements, a high standard in the selection of the enzymes with the objective of avoiding the formation of soaps, creating in this way cleaner products and sub-products, in which the separation of the phases biodiesel/glycerol, give the possibility to recuperate the bio catalyzer and high output of reactions. However, the high volume of medium required to obtain lipids is one of the major drawbacks to test the viability of these enzymes. The present study aims to design an enzymatic transesterification process for the production of biodiesel form synthetic Chlorella oil. The synthetic oil was designed according to the lipid profile of C 16:0, C16:1, C18:0, C18:1, C18:2 and C18:3 from Chlorella spp CHL2 cultured on Bold Basal media under limited concentrations of NaNO3. The enzymatic transesterification efficiency was evaluated by the implementation of a 22 experimental factorial design (temperature and lipase concentration) under a 3: 1 molar ratio of alcohol:oil and a fixed reaction time of 6 hours. The obtained results show that, in order to obtain superior yields of biodiesel (>91%) the transesterification process must be carried out under temperature conditions close to 38°C and lipase concentrations of 5%

Cannabidiol Enhances the Passage of Lipid Nanocapsules across the Blood–Brain Barrier Both in Vitro and in Vivo

Diseases affecting the central nervous system (CNS) should be regarded as a major health challenge due to the current lack of effective treatments given the hindrance to brain drug delivery imposed by the blood–brain barrier (BBB). Since efficient brain drug delivery should not solely rely on passive targeting, active targeting of nanomedicines into the CNS is being explored. The present study is devoted to the development of lipid nanocapsules (LNCs) decorated with nonpsychotropic cannabinoids as pioneering nonimmunogenic brain-targeting molecules and to the evaluation of their brain-targeting ability both in vitro and in vivo. Noticeably, both the permeability experiments across the hCMEC/D3 cell-based in vitro BBB model and the biodistribution experiments in mice consistently demonstrated that the highest brain-targeting ability was achieved with the smallest-sized cannabinoid-decorated LNCs. Importantly, the enhancement in brain targeting achieved with the conjugation of cannabidiol to LNCs outperformed by 6-fold the enhancement observed for the G-Technology (the main brain active strategy that has already entered clinical trials for the treatment of CNS diseases). As the transport efficiency across the BBB certainly determines the efficacy of the treatments for brain disorders, small cannabinoid-decorated LNCs represent auspicious platforms for the design and development of novel therapies for CNS diseases

Detecting individual gravity modes in the Sun: Chimera or reality?

Over the past 15 years, our knowledge of the interior of the Sun has tremendously progressed by the use of helioseismic measurements. However, to go further in our understanding of the solar core, we need to measure gravity (g) modes. Thanks to the high quality of the Doppler-velocity signal measured by GOLF/SoHO, it has been possible to unveil the signature of the asymptotic properties of the solar g modes, thus obtaining a hint of the rotation rate in the core. However, the quest for the detection of individual g modes is not yet over. In this work, we apply the latest theoretical developments to guide our research using GOLF velocity time series. In contrary to what was thought till now, we are maybe starting to identify individual low-frequency g modes...Comment: Highlight of Astronomy (HoA) proceedings of the JD-11, IAU 2009. 2 pages, 1 figur