3 research outputs found
The interplay between functioning problems and symptoms in first episode of psychosis: an approach from network analysis
The relationship between psychotic symptoms and global measures of functioning has been widely studied. No previous study has assessed so far the interplay between specific clinical symptoms and particular areas of functioning in first-episode psychosis (FEP) using network analysis methods. A total of 191 patients with FEP (age 24.45 ± 6.28 years, 64.9% male) participating in an observational and longitudinal study (AGES-CM) comprised the study sample. Functioning problems were assessed with the WHO Disability Assessment Schedule (WHODAS), whereas the Positive and Negative Syndrome Scale (PANSS) was used to assess symptom severity. Network analysis were conducted with the aim of analysing the patterns of relationships between the different dimensions of functioning and PANSS symptoms and factors at baseline. According to our results, the most important nodes were âconceptual disorganizationâ, âemotional withdrawalâ, âlack of spontaneity and flow of conversationâ, âdelusionsâ, âunusual thought contentâ, âdealing with strangersâ and âpoor rapportâ. Our findings suggest that these symptoms and functioning dimensions should be prioritized in the clinical assessment and management of patients with FEP. These areas may also become targets of future early intervention strategies, so as to improve quality of life in this populationThis work was supported by the Madrid Regional Government (R&D
activities in Biomedicine (grant number S2017/BMD-3740 - AGES-CM
2-CM)) and Structural Funds of the European Union. Ana Izquierdoâs
work is supported by the PFIS predoctoral program (FI17/00138) from
the Instituto de Salud Carlos III (Spain) and co-funded by the European
Union (ERDF/ESF, "A way to make Europeâ/ âInvesting in your futureâ)
and The Biomedical Research Foundation of La Princesa University Hospital.
Angela IbÂŽaËnez thanks the support of CIBERSAM and of the Spanish
Ministry of Science, Innovation and Universities. Instituto de Salud
Carlos III (PI16/00834 and PI19/01295) co-financed by ERDF Funds
from the European Commission. Covadonga M. DĂaz-Caneja holds a
Juan RodÂŽes Grant from Instituto de Salud Carlos III (JR19/00024). Celso
Arango was supported by the Spanish Ministry of Science and Innovation.
Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/
024), co-financed by ERDF Funds from the European Commission, âA
way of making Europeâ, CIBERSAM. Madrid Regional Government
(B2017/BMD-3740 AGES-CM-2), European Union Structural Funds.
European Union Seventh Framework Program under grant agreements
FP7-4-HEALTH-2009-2.2.1-2-241909 (Project EU-GEI), FP7- HEALTH-
2013-2.2.1-2-603196 (Project PSYSCAN) and FP7- HEALTH-2013-
2.2.1-2-602478 (Project METSY); and European Union H2020 Program
under the Innovative Medicines Initiative 2 Joint Undertaking
(grant agreement No 115916, Project PRISM, and grant agreement No
777394, Project AIMS-2-TRIALS), FundaciÂŽon Familia Alonso, FundaciÂŽon
Alicia Koplowitz and FundaciÂŽon Mutua MadrileËn
PsicologĂa de la santidad femenina
El objetivo de esta tesis es intentar demostrar que existe un perfil psicolĂłgico comĂșn de santidad femenina, modulada por los avatares histĂłricos y culturales siendo la santidad, al menos en los Ășltimos siglos, una virtud propia de la mujer. Si dicho objetivo se confirma y es considerado pertinente, interesa encuadrarlo, en el marco general de las alteraciones psiquiĂĄtricas de gĂ©nero. En definitiva, se ha intentado conocer mejor las conductas, muchas veces extraordinarias y otras atormentadas, de un grupo de mujeres cuyas biografĂas sedujeron sin duda a los jueces de la iglesia que las elevaron a la condiciĂłn de santas. Para ello hemos analizado desde su nacimiento hasta su muerte, en lo que es posible, la vida de sesenta mujeres religiosas, a travĂ©s de biografĂas y autobiografĂas ya se tratara de siervas, beatas o santas segĂșn la terminologĂa eclesiĂĄstica.De este conjunto fue inevitable seleccionar doce casos, que son los que se exponen de manera exhaustiva en este estudio. Son los que disponen de un material biogrĂĄfico mĂĄs aprovechable y fiable, y son aquĂ©llos en los que existe informaciĂłn directa de la propia santa o se enfrentan con biografĂas contrastadas y aliviadas de sus excesos panegĂricos. Una vez extraĂdos los caracteres mĂĄs relevantes, se han comparado estos datos entre todas ellas tratando de construir un modelo de santidad que posteriormente hemos enfrentado con los conocimientos psiquiĂĄtricos actuales, a la vez que hemos instalado estas biografĂas en su dimensiĂłn histĂłrica
The interplay between functioning problems and symptoms in first episode of psychosis: An approach from network analysis
The relationship between psychotic symptoms and global measures of functioning has been widely studied. No previous study has assessed so far the interplay between specific clinical symptoms and particular areas of functioning in first-episode psychosis (FEP) using network analysis methods. A total of 191 patients with FEP (age 24.45âŻÂ±âŻ6.28 years, 64.9% male) participating in an observational and longitudinal study (AGES-CM) comprised the study sample. Functioning problems were assessed with the WHO Disability Assessment Schedule (WHODAS), whereas the Positive and Negative Syndrome Scale (PANSS) was used to assess symptom severity. Network analysis were conducted with the aim of analysing the patterns of relationships between the different dimensions of functioning and PANSS symptoms and factors at baseline. According to our results, the most important nodes were âconceptual disorganizationâ, âemotional withdrawalâ, âlack of spontaneity and flow of conversationâ, âdelusionsâ, âunusual thought contentâ, âdealing with strangersâ and âpoor rapportâ. Our findings suggest that these symptoms and functioning dimensions should be prioritized in the clinical assessment and management of patients with FEP. These areas may also become targets of future early intervention strategies, so as to improve quality of life in this population.Depto. de PsicobiologĂa y MetodologĂa en Ciencias del ComportamientoFac. de PsicologĂaTRUEpu