Chemical composition and antifungal activity of the essential oil from Piper amalago L.

The essential oil obtained from the leaves of Piper amalago L. by hydrodistillation was analyzed by CG-MS. The yield essential oil from fresh plant material was 0.1%. The main compounds found were β-copaen-4-α-ol (26 %), 7-epi-α-eudesmol (21.84 %), epi-α-cadinol (12.70 %), and n-hexyl-benzoate (12.29 %). The essential oil demonstrated antifungal activity against nine Candida strains, as shown using the agar-diffusion method.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Toxicological and pharmacological studies of Picrasma crenata (Vell.) Engler (Simaroubaceae) in mice and rats

Se investigó la toxicidad, actividad anti-inflamatória, anti-úlcera, anti-hiperglucemiante, hipoglucemiante y anti-hiperlipidémica del extracto hidroalcohólico de tallo (sin corteza) de Picrasma crenata (Vell.) Engler (Simaroubaceae). El extracto presentó baja toxicidad en ratones. Además, de acuerdo al uso popular de esta espécie en el tratamiento de la gastritis y de la diabetes mellitus, se observo um efecto anti-úlcera e hipoglucemiante en ratas. Sin embargo, no fue observado ningún efecto anti-inflamatório, anti-hiperglucémico ni anti-hiperlipidámico en estos animales.The toxicity and the anti-inflammatory, anti-ulcer, anti-hyperglycemic, hypoglycemic and anti-hyperlipidemic effect of the hydroalcoholic extract from woods (without bark) of Picrasma crenata (Vell.) Engler (Simaroubaceae) were investigated. The extract showed low toxicity in mice. Additionally, in agreement with the popular use to treat gastric ulcer and diabetes, anti-ulcer and blood glucose lowering effect were detected in rats. However, anti-inflammatory, anti-hyperglycemic and anti-hyperlipidemic effects were not observed in these animals.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Pharmacobotanical study of the aerial organs of the Achyrocline alata DC. (Asteraceae)

Achyrocline alata DC. (Asteraceae) conhecida como macela, güira-güira ou jatei-kaá espécie medicinal que ocorre no Brasil, é popularmente utilizada em casos de infecções respiratórias, resfriados, infecções no útero e próstata, hérnia, dores no estômago, labirintite, apendicite e bronquite. Devido a grande semelhança entre as espécies de Achyrocline, realizou-se a descrição anatômica das partes aéreas de A. alata, visando estabelecer parâmetros para a analise botânica da referida planta. Lâminas semipermanentes e permanentes foram confeccionadas segundo técnicas usuais de corte e coloração. Os capítulos são heteromorfos com flores do raio femininas em número de seis a oito, e flores do disco hermafroditas variando de uma a três. A folha é anfiestomática, os estômatos anomocíticos e o mesofilo isobilateral. Em toda a parte aérea ocorrem tricomas tectores, pluricelulares e unisseriados e glandulares, com pedúnculo bisseriado e cabeça secretora bicelular.Achyro - cline alata DC. (Asteraceae), known as "macela", "güira-güira" or "jatei-kaá", a folk medicinal plant that occurs in Brazil is popularly used in cases of breathing infections, colds, uterus and prostate infections, hernia, stomach pains, labyrinthine, appendicitis and bronchitis. Due to the great similarity among the species of Achyrocline, anatomical descriptions of the stem, leaf and inflorescences of A. alata were made, with the purpose to establish parameters for the botanical analysis of the referred plant. Anatomical description was accomplished through permanent and semi-permanents slides mounted according standard procedures. The capitulum is heteromorphy, with ray pistillates florets in number of six to eight, and disk hermaphroditics florets varying of one to three. The isobilateral leaf presents anomocytics stomata in both surfaces. In all aerial part nonglandular, multicellular and uniseriate trichomes, and glandular with biseriate stalk and secretory head with two ovoid cells occurs.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Pharmacobotanical study of the aerial organs of the Achyrocline alata DC. (Asteraceae)

Achyrocline alata DC. (Asteraceae) conhecida como macela, güira-güira ou jatei-kaá espécie medicinal que ocorre no Brasil, é popularmente utilizada em casos de infecções respiratórias, resfriados, infecções no útero e próstata, hérnia, dores no estômago, labirintite, apendicite e bronquite. Devido a grande semelhança entre as espécies de Achyrocline, realizou-se a descrição anatômica das partes aéreas de A. alata, visando estabelecer parâmetros para a analise botânica da referida planta. Lâminas semipermanentes e permanentes foram confeccionadas segundo técnicas usuais de corte e coloração. Os capítulos são heteromorfos com flores do raio femininas em número de seis a oito, e flores do disco hermafroditas variando de uma a três. A folha é anfiestomática, os estômatos anomocíticos e o mesofilo isobilateral. Em toda a parte aérea ocorrem tricomas tectores, pluricelulares e unisseriados e glandulares, com pedúnculo bisseriado e cabeça secretora bicelular.Achyro - cline alata DC. (Asteraceae), known as "macela", "güira-güira" or "jatei-kaá", a folk medicinal plant that occurs in Brazil is popularly used in cases of breathing infections, colds, uterus and prostate infections, hernia, stomach pains, labyrinthine, appendicitis and bronchitis. Due to the great similarity among the species of Achyrocline, anatomical descriptions of the stem, leaf and inflorescences of A. alata were made, with the purpose to establish parameters for the botanical analysis of the referred plant. Anatomical description was accomplished through permanent and semi-permanents slides mounted according standard procedures. The capitulum is heteromorphy, with ray pistillates florets in number of six to eight, and disk hermaphroditics florets varying of one to three. The isobilateral leaf presents anomocytics stomata in both surfaces. In all aerial part nonglandular, multicellular and uniseriate trichomes, and glandular with biseriate stalk and secretory head with two ovoid cells occurs.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Petiveria alliacea L.: plant drug quality control, hydroalcoholic extract standardization and pharmacological assay of lyophilized extract

La población nativa del Brasil utiliza extractos fluidos, decocción e infusión de las raíces y hojas de Petiveria alliaceae L. (Phytolacaceae, guiné) ante a los más diferentes tipos de síntomas y también como sedativo. Se realizaron experimentos en ratas para verificar la actividad analgésica y anticonvulsiva de extractos acuosos e infusión de las raíces. Por otro lado, no hay estudios de estandarización de los extractos y tampoco de la droga vegetal. El objetivo de este trabajo fue el de evaluar las partes aéreas del "guiné" y su turboextracto desde el punto de vista del control de calidad, actividad ansiolítica y protección de lesiones gástricas por estrés, así como el turboextracto estandarizado. Los resultados en animales sugieren que las partes aéreas de "guiné" contienen componentes con efectos ansiolíticos y de protección de las lesiones gástricas por estrés. La granulometría de 0,630 mm y la proporción planta:solvente a 20% (m/V) fueron los factores que determinaron la más alta concentración de flavonoides en el extracto turbolizado.Preparations such as fluid extract decoction and infusion of roots and leaves from Petiveria alliacea L.(Phytolacaceae) known popularly as guiné have been used by the population for the most different symptoms and even as sedative. Though experiments have been carried out and verified the analgesic and anticonvulsive action of roots aqueous and infused extract in mice, there are no studies on standardization for both plant drugs and their extract solutions. The aim of the present study was to evaluate the aerial parts of guiné plant drug and its turbo-extract in respect to its quality control, anxiolytic and stress gastric lesions protective activities, and the standardized turbo-extract. The results suggest anxiolytic and stress gastric lesion protective effect for aerial parts extract of P. alliucea in animals. A 0.630 mm granulometry and a 20% (m/V)plant: solvent proportion were the factors that determined the highest yield of total flavonoid content in turbo-extract in the present experiment.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Petiveria alliacea L.: plant drug quality control, hydroalcoholic extract standardization and pharmacological assay of lyophilized extract

La población nativa del Brasil utiliza extractos fluidos, decocción e infusión de las raíces y hojas de Petiveria alliaceae L. (Phytolacaceae, guiné) ante a los más diferentes tipos de síntomas y también como sedativo. Se realizaron experimentos en ratas para verificar la actividad analgésica y anticonvulsiva de extractos acuosos e infusión de las raíces. Por otro lado, no hay estudios de estandarización de los extractos y tampoco de la droga vegetal. El objetivo de este trabajo fue el de evaluar las partes aéreas del "guiné" y su turboextracto desde el punto de vista del control de calidad, actividad ansiolítica y protección de lesiones gástricas por estrés, así como el turboextracto estandarizado. Los resultados en animales sugieren que las partes aéreas de "guiné" contienen componentes con efectos ansiolíticos y de protección de las lesiones gástricas por estrés. La granulometría de 0,630 mm y la proporción planta:solvente a 20% (m/V) fueron los factores que determinaron la más alta concentración de flavonoides en el extracto turbolizado.Preparations such as fluid extract decoction and infusion of roots and leaves from Petiveria alliacea L.(Phytolacaceae) known popularly as guiné have been used by the population for the most different symptoms and even as sedative. Though experiments have been carried out and verified the analgesic and anticonvulsive action of roots aqueous and infused extract in mice, there are no studies on standardization for both plant drugs and their extract solutions. The aim of the present study was to evaluate the aerial parts of guiné plant drug and its turbo-extract in respect to its quality control, anxiolytic and stress gastric lesions protective activities, and the standardized turbo-extract. The results suggest anxiolytic and stress gastric lesion protective effect for aerial parts extract of P. alliucea in animals. A 0.630 mm granulometry and a 20% (m/V)plant: solvent proportion were the factors that determined the highest yield of total flavonoid content in turbo-extract in the present experiment.Colegio de Farmacéuticos de la Provincia de Buenos Aire