The distribution of O and N in the surface region of laser-patterned titanium revealed by atom probe tomography

Direct Laser Interference Lithography (DLIL) has shown to be a promising technique to chemically and physically alter the surface of titanium. In this work, atom probe tomography analysis was performed on DLIL-treated titanium to obtain the chemical composition of the surface in maxima and minima interference positions. The analysis revealed that a multilayer structure consisting of oxide/oxynitride is formed at both positions; however, the chemical composition is altered differently between the two. The observed difference is believed to be due to an uneven heating and temperature distribution, which is demonstrated by thermal simulations

Scattering of Dirac particles from non-local separable potentials: the eigenchannel approach

An application of the new formulation of the eigenchannel method [R. Szmytkowski, Ann. Phys. (N.Y.) {\bf 311}, 503 (2004)] to quantum scattering of Dirac particles from non-local separable potentials is presented. Eigenchannel vectors, related directly to eigenchannels, are defined as eigenvectors of a certain weighted eigenvalue problem. Moreover, negative cotangents of eigenphase-shifts are introduced as eigenvalues of that spectral problem. Eigenchannel spinor as well as bispinor harmonics are expressed throughout the eigenchannel vectors. Finally, the expressions for the bispinor as well as matrix scattering amplitudes and total cross section are derived in terms of eigenchannels and eigenphase-shifts. An illustrative example is also provided.Comment: Revtex, 9 pages, 4 figures, published versio

A functional variant in the Stearoyl-CoA desaturase gene promoter enhances fatty acid desaturation in pork

There is growing public concern about reducing saturated fat intake. Stearoyl-CoA desaturase (SCD) is the lipogenic enzyme responsible for the biosynthesis of oleic acid (18:1) by desaturating stearic acid (18:0). Here we describe a total of 18 mutations in the promoter and 3′ non-coding region of the pig SCD gene and provide evidence that allele T at AY487830:g.2228T>C in the promoter region enhances fat desaturation (the ratio 18:1/18:0 in muscle increases from 3.78 to 4.43 in opposite homozygotes) without affecting fat content (18:0+18:1, intramuscular fat content, and backfat thickness). No mutations that could affect the functionality of the protein were found in the coding region. First, we proved in a purebred Duroc line that the C-T-A haplotype of the 3 single nucleotide polymorphisms (SNPs) (g.2108C>T; g.2228T>C; g.2281A>G) of the promoter region was additively associated to enhanced 18:1/18:0 both in muscle and subcutaneous fat, but not in liver. We show that this association was consistent over a 10-year period of overlapping generations and, in line with these results, that the C-T-A haplotype displayed greater SCD mRNA expression in muscle. The effect of this haplotype was validated both internally, by comparing opposite homozygote siblings, and externally, by using experimental Duroc-based crossbreds. Second, the g.2281A>G and the g.2108C>T SNPs were excluded as causative mutations using new and previously published data, restricting the causality to g.2228T>C SNP, the last source of genetic variation within the haplotype. This mutation is positioned in the core sequence of several putative transcription factor binding sites, so that there are several plausible mechanisms by which allele T enhances 18:1/18:0 and, consequently, the proportion of monounsaturated to saturated fat.This research was supported by grants from the Spanish Ministry of Science and Innovation (AGL2009-09779 and AGL2012-33529). RRF is recipient of a PhD scholarship from the Spanish Ministry of Science and Innovation (BES-2010-034607). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of manuscript