1 research outputs found
Dioxygen-Triggered Oxidative Radical Reaction: Direct Aerobic Difunctionalization of Terminal Alkynes toward β‑Keto Sulfones
An
unprecedented dioxygen-triggered oxidative radical process was
explored using dioxygen as the solely terminal oxidant, realizing
aerobic oxidaitve difunctionalization of terminal alkynes toward β-keto
sulfones with high selectivity. Operando IR experiments revealed that
pyridine not only acts as a base to successfully surpress ATRA (atom
transfer radical addition) process, but also plays a vital role in
reducing the activity of sulfinic acids