COMPLICATIONS RELATED COMORBIDITIES OF ARTERIOVENOUS FISTULA (AVF) CREATION AS HEMODIALYSIS ACCESS FOR END STAGE RENAL DISEASE (ESRD) IN BEN MBOI DISTRICT HOSPITAL, RUTENG FLORES INDONESIA

Introduction: Since Brescia and Cimino(1966) posted AV Fistula technique, there has been increase of long term survival of patients with End Stage Renal Disease (ESRD). AV fistula has its own set of indications, benefits, and complications. Purpose: To show AV Fistula creation outcomes, complications and its related comorbidities in Ben Mboi District Hospital, Ruteng Flores IndonesiaMethod: An analytical study design using a cross sectional approach was employed in this study. Using medical record data from 2019 to 2022, all men and women who received hemodialysis through AV Fistula were included. Bivariate analysis was carried out from baseline data such as age, sex, comorbidities, location of an av fistula (AVF), previous dialysis insertion with complications that arise using Chi-square. Results: Age, sex, hypertension and AV Fistula creation location has no significant correlation with complications such as failed to mature, thrombosis, infection, venous hypertension. Diabetes mellitus has a significant correlation with occurrence of failed to mature (p=0.012), thrombosis (p=0.014), venous hypertension (p=0.08). Obesity has a significant correlation with occurrence of failed to mature (p=0.000), thrombosis (p=0.000). Previous insertion of CDL in right subclavian vein has a significant correlation with occurrence of venous hypertension (p=0.000).Conclusion: Diabetes mellitus has a significant correlation with occurrence of complications such as failed to mature, thrombosis and venous hypertension. Obesity has a significant correlation with occurrence of failed to mature and thrombosis. History of CDL insertion in right subclavian vein has a significant correlation with venous hypertension

Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Native Patients with HIV/AIDS Infection at Tertiary Hospital

The increased cortisol is significantly correlated with HIV mortality. The objective of this study was to analyze the correlation between serum cortisol levels and CD4 counts in treatment-naïve patients with HIV/AIDS infection. This was an analytical cross-sectional study. Total serum cortisol levels were measured by ADVIA Centaur® using chemiluminescence immunoassay and CD4 counts were measured by flow cytometry technique using BD FACS Count CD4 reagants®. Among 56 samples of treatment-naïve patients with HIV/AIDS infection, the mean age was 34.3 ± 9 years and they were predominantly male. Mean total cortisol levels was 18.88 ± 9.90 µg/dL, and 32.1% of samples had total cortisol levels of >22.4 µg/dL. As much as 67.9% of the samples presented CD4 counts lower than 200 cells/mm3. There was a significant moderate negative correlation between total cortisol levels and CD4 counts (r = -0.467, p<0.001).Total cortisol levels were negatively correlated with CD4 counts. The higher the total cortisol levels of HIV/AIDS-positive patients, the lower the CD4 counts