16 research outputs found

    Robust Image Watermarking Using QR Factorization In Wavelet Domain

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    A robust blind image watermarking algorithm in wavelet transform domain (WT) based on QR factorization, and quantization index modulation (QIM) technique is presented for legal protection of digital images. The host image is decomposed into wavelet subbands, and then the approximation subband is QR factorized. The secret watermark bit is embedded into the R vector in QR using QIM. The experimental results show that the proposed algorithm preserves the high perceptual quality. It also sustains against JPEG compression, and other image processing attacks. The comparison analysis demonstrates the proposed scheme has better performance in imperceptibility and robustness than the previously reported watermarking algorithms

    Recurrent Herpes Zoster in Early Childhood

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    Herpes Zoster is produced by reactivation of latent Varicella Zoster Virus from the dorsal root ganglion of sensory nerves. It is common in older individuals and rarely described in the pediatric age group. We report a case of recurrent herpes zoster in a 3-year-old HIV positive child involving T 4 dermatome on the first occasion and subsequently involving T 10 dermatome. The child responded well to oral acyclovir

    Persistence of Stunting After Highly Active Antiretroviral Therapy in HIV-Infected Children in South India

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    After one year of antiretroviral treatment in 49 HIV-infected children compared to 53 children without, weight for age improved significantly and was highly correlated with baseline immune status and CD4% increase but height for age did not change. Stunting is a common feature of pediatric HIV, both on and off HAART

    Rapid Progression of HIV Infection in Infancy

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    Transmission of HIV from mother to child can occur in utero, during labor or after delivery via breast feeding. Data on the fate of babies born with HIV in India are scarce. We present details of 25 infants with perinatally acquired HIV infection (virologically confirmed) to highlight the observed high rate of morbidity and mortality within the first 18 months of life. Our findings of rapid disease progression among perinatally infected HIV positive children underline the importance of early diagnosis and treatment

    High-risk human papillomavirus infection and E6 protein expression in Lesions of the Uterine cervix

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    Pathologic and epidemiologic investigations carried out over the past several years have provided evidence that carcinogenesis in the uterine cervix is a multi-step process involving discreet preinvasive stages. Molecular epidemiologic data also indicate that human papillomavirus (HPV) infection is a critical factor in the tumor progression process. In vitro studies have shown that for the initiation and maintenance of the malignant phenotype, the expression of the HPV-transforming protein E6 is required. The E6 protein produced by the high-risk HPV types 16 and 18 can bind to and inactivate the tumor suppressor protein p53 leading to deregulated proliferation and defective apoptosis, thus facilitating tumor progression. Therefore, determination of the HPV genotype alone may not be sufficient in assessing tumor progression in the uterine cervix. In the present study, a total of 623 cervical tissue samples at various phases of tumor progression were assessed for HPV infection by nonisotopic in situ hybridization (NISH) and for HPV 16/18 E6 protein expression by immunocytochemistry. There was significant correlation between the extent of histological abnormality and HPV infection. Significant correlation (r = 0.707, p = 0.000) was observed between the presence of HPV 16 and high-grade squamous intraepithelial lesions (SILs) and invasive cancer. The odds ratio of a cervical tissue infected with HPV 16 falling into these two categories was 44.57 (95% CI: 27.10, 73.30). The E6 protein also was mostly detected in high-grade SILs and cervical cancer tissue expressing either HPV 16 or 18. It was less frequent in low-grade SILs infected with HPV 16/18 and was absent in benign cervical tissue infected with HPV 16. The odds ratio of an HPV-16/18-infected cervical tissue positive for E6 being a high-grade SIL or invasive cancer was 16.20 (95% CI: 6.06, 43.33). These results thus show the clinical utility of HPV characterization along with the analysis of the transforming protein E6 in the assessment of tumor progression in the uterine cervix
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