30 research outputs found
Demographics, clinical characteristics and hematological findings in the study population.
<p>Data are presented as the number of subjects in each group, with percentages given in parentheses or mean, with SD given in parentheses.</p><p><sup>a</sup> Date were collected at the onset of IFD and bacterial sepsis, or about postnatal age of 21 days for preterm control infants.</p><p><sup>b</sup>Comparison between IFD vs preterm control <i>p</i><0.05</p><p><sup>c</sup>Comparison between IFD vs bacterial sepsis <i>p</i><0.05</p><p><sup>d</sup>Comparison between bacterial sepsis vs preterm control <i>p</i><0.05</p><p>Demographics, clinical characteristics and hematological findings in the study population.</p
Receiver operating characteristic curves for predicting mortality in IFD infants by platelet count (PC) and plateletcrit (PCT).
<p>For each indicator, sensitivity (true positive rate) is plotted against 1-specificity (false positive rate). Accuracy is measured by the area under the ROC curve. The AUCs for PC and PCT were 0.775 (95% CI: 0.629–0.920, p = .002) and 0.765 (95% CI: 0.610–0.921, p = .006), respectively.</p
Receiver operating characteristic curves for the diagnosis of IFD by four platelet parameters.
<p>For each indicator, sensitivity (true positive rate) is plotted against 1-specificity (false positive rate). Accuracy is measured by the area under the ROC curve. Platelet count (PC) and plateletcrit (PCT) showed better accuracy than platelet distribution width (PDW) and hemoglobin (MPV).</p
ROC analysis for the prediction of IFD by platelet parameters using the cutoffs with the maximal sum of sensitivity and specificity.
<p>AUC = area under the curve</p><p>ROC analysis for the prediction of IFD by platelet parameters using the cutoffs with the maximal sum of sensitivity and specificity.</p
Birth, clinical characteristics and hematological findings in deceased versus survived IFD at the onset and 14 days after antifungal therapy in survived IFD infants.
<p>Data are presented as the number of subjects in each group, with percentages given in parentheses or mean, with SD given in parentheses.</p><p><sup>a</sup><i>P</i>1 values compares the deceased IFD with the survived IFD.</p><p><sup>b</sup><i>P</i>2 values compares hematological parameters at the onset day and at the 14<sup>th</sup> day after antifungal treatment in the survived IFD.</p><p>Birth, clinical characteristics and hematological findings in deceased versus survived IFD at the onset and 14 days after antifungal therapy in survived IFD infants.</p
Ferroelectric Field-Effect Transistors Based on MoS<sub>2</sub> and CuInP<sub>2</sub>S<sub>6</sub> Two-Dimensional van der Waals Heterostructure
We
demonstrate room-temperature ferroelectric field-effect transistors
(Fe-FETs) with MoS<sub>2</sub> and CuInP<sub>2</sub>S<sub>6</sub> two-dimensional
(2D) van der Waals heterostructure. The ferroelectric CuInP<sub>2</sub>S<sub>6</sub> is a 2D ferroelectric insulator, integrated on top
of MoS<sub>2</sub> channel providing a 2D/2D semiconductor/insulator
interface without dangling bonds. The MoS<sub>2</sub>- and CuInP<sub>2</sub>S<sub>6</sub>-based 2D van der Waals heterostructure Fe-FETs
exhibit a clear counterclockwise hysteresis loop in transfer characteristics,
demonstrating their ferroelectric properties. This stable nonvolatile
memory property can also be modulated by the back-gate bias of the
MoS<sub>2</sub> transistors because of the tuning of capacitance matching
between the MoS<sub>2</sub> channel and the ferroelectric CuInP<sub>2</sub>S<sub>6</sub>, leading to the enhancement of the on/off current
ratio. Meanwhile, the CuInP<sub>2</sub>S<sub>6</sub> thin film also
shows resistive switching characteristics with more than four orders
of on/off ratio between low- and high-resistance states, which is
also promising for resistive random-access memory applications
Additional file 1: Table S1. of Long non-coding RNA MALAT1 protects preterm infants with bronchopulmonary dysplasia by inhibiting cell apoptosis
List of differentially expressed genes in GSE25286 (XLSX 157 kb
Additional file 2: Table S2. of Long non-coding RNA MALAT1 protects preterm infants with bronchopulmonary dysplasia by inhibiting cell apoptosis
List of differentially expressed genes in GSE43830 (XLSX 56 kb
One-Dimensional van der Waals Material Tellurium: Raman Spectroscopy under Strain and Magneto-Transport
Experimental
demonstrations of one-dimensional (1D) van der Waals
material tellurium (Te) have been presented by Raman spectroscopy
under strain and magneto-transport. Raman spectroscopy measurements
have been performed under strains along different principle axes.
Pronounced strain response along the <i>c</i>-axis is observed
due to the strong intrachain covalent bonds, while no strain response
is obtained along the <i>a</i>-axis due to the weak interchain van der Waals interaction. Magneto-transport
results further verify its anisotropic property, which results in
dramatically distinct magneto-resistance behaviors in terms of three
different magnetic field directions. Specifically, phase coherence
length extracted from weak antilocalization effect, <i>L</i><sub>ϕ</sub> ≈ <i>T</i><sup>–0.5</sup>, claims its two-dimensional (2D) transport characteristics when
an applied magnetic field is perpendicular to the thin film. In contrast, <i>L</i><sub>ϕ</sub> ≈ <i>T</i><sup>–0.33</sup> is obtained from universal conductance fluctuations once the magnetic
field is along the <i>c</i>-axis of Te, which indicates
its nature of 1D transport along the helical atomic chains. Our studies,
which are obtained on high quality single crystal Te thin film, appear
to serve as strong evidence of its 1D van der Waals structure from
experimental perspectives. It is the aim of this paper to address
this special concept that differs from the previous well-studied 1D
nanowires or 2D van der Waals materials
Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter-7
<p><b>Copyright information:</b></p><p>Taken from "Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter"</p><p>http://www.aidsrestherapy.com/content/4/1/24</p><p>AIDS Research and Therapy 2007;4():24-24.</p><p>Published online 17 Oct 2007</p><p>PMCID:PMC2211285.</p><p></p>erent HIV-1 specific RT aptamers transcriptionally regulated by the U6+1 promoter positioned in the antisense orientation. The forward and reverse arrows above GFP and the 3' UTR represent the PCR primers used to amplify the inhibitor cassette in transduced cells. B) Generation of high-titer producer cell lines by shuttle packaging. Vector plasmids were transiently transfected into Phoenix (GaLV) packaging cell line and supernatant was used to transduce Phoenix (amphotropic) packaging cell lines. After selecting for Phoenix (amphotropic) cells expressing GFP, supernatants were collected for titering and to transduce Phoenix (GaLV) packaging cell lines with 2 exposures. Supernatants from these Phoenix (GaLV) cells were collected for titration and to transduce the CD4cell line CEMx174