Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients

Tumor associated antigens are useful in colorectal cancer (CRC) management. The ribosomal P proteins (P0, P1, P2) play an important role in protein synthesis and tumor formation. The immunogenicity of the ribosomal P0 protein in head and neck, in breast and prostate cancer patients and the overexpression of the carboxyl-terminal P0 epitope (C-22 P0) in some tumors were reported

Neoplasia cística mucinosa do pâncreas durante a gestação: Relato de Caso Mucinous cystic neoplasm of the pancreas during pregnancy: Case Report

O objetivo deste estudo é relatar o caso de uma gestante de 20 anos portadora de neoplasia cística mucinosa do pâncreas. Evidências sugerem que essa neoplasia é dependente dos hormônios estrógeno-progesterona levando a um importante crescimento durante a gestação e ainda apresentar, mesmo baixo, um potencial para degeneração maligna. O motivo deste relato é a raridade da doença associada a gestação em uma paciente tão jovem. Foi realizada pancreatectomia corpo-caudal no segundo trimestre da gestação com boa evolução materna e fetal.<br>The aim of this study is to report the case of a 20 years old pregnant woman with a mucinous cystic neoplasm of the pancreas. Evidence suggests that this neoplasm is dependent on estrogen-pro-gesterone leading to a significant growth during pregnancy and beyond this a potential malignant degeneration, even low. The reason of this case-study is the rarity of the disease associated with pregnancy in a patient so young. A body-tail pancreatectomy was performed in the second trimester of pregnancy with good maternal and fetal outcomes