An Intelligent Agent Based Intrusion Detection System Using Fuzzy Rough Set Based Outlier Detection

Since existing Intrusion Detection Systems (IDS) including misuse detection and anomoly detection are generally incapable of detecting new type of attacks. However, all these systems are capable of detecting intruders with high false alarm rate. It is an urgent need to develop IDS with very high Detection rate and with low False alarm rate. To satisfy this need we propose a new intelligent agent based IDS using Fuzzy Rough Set based outlier detection and Fuzzy Rough set based SVM. In this proposed model we intorduced two different inteligent agents namely feature selection agent to select the required feature set using fuzzy rough sets and decision making agent manager for making final decision. Moreover, we have introduced fuzzy rough set based outlier detection algorithm to detect outliers. We have also adopted Fuzzy Rough based SVM in our system to classify and detect anomalies efficiently. Finally, we have used KDD Cup 99 data set for our experiment, the experimental result show that the proposed intelligent agent based model improves the overall accuracy and reduces the false alarm rate

Exergy Analysis of Operating Lignite Fired Thermal Power Plant

The energy assessment must be made through the energy quantity as well as the quality. But the usual energy analysisevaluates the energy generally on its quantity only. However, the exergy analysis assesses the energy on quantity as well asthe quality. The aim of the exergy analysis is to identify the magnitudes and the locations of real energy losses, in order toimprove the existing systems, processes or components. The present paper deals with an exergy analysis performed on anoperating 50MWe unit of lignite fired steam power plant at Thermal Power Station-I, Neyveli Lignite Corporation Limited,Neyveli, Tamil Nadu, India. The exergy losses occurred in the various subsystems of the plant and their components havebeen calculated using the mass, energy and exergy balance equations. The distribution of the exergy losses in several plantcomponents during the real time plant running conditions has been assessed to locate the process irreversibility. The Firstlaw efficiency (energy efficiency) and the Second law efficiency (exergy efficiency) of the plant have also been calculated.The comparison between the energy losses and the exergy losses of the individual components of the plant shows that themaximum energy losses of 39% occur in the condenser, whereas the maximum exergy losses of 42.73% occur in the combustor.The real losses of energy which has a scope for the improvement are given as maximum exergy losses that occurredin the combustor

Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering

We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations. We determine as a function of generation such structural properties as: radius of gyration, shape tensor, asphericity, fractal dimension, monomer density distribution, and end-group distribution functions. The sizes obtained from the MD simulations have been validated by Small Angle X-Ray Scattering (SAXS) experiment on dendrimer of generation 2 to 4 (G2-G4). A good agreement between the experimental and theoretical value of radius of gyration has been observed. We find a linear increase in radius of gyration with the generation. In contrast, Rg scales as ~ N^x with the number of monomers. We find two distinct exponents depending on the generations: x = 0.47 for G1-G3 and x = 0.28 for G3-G6 which reveals their non-space filling nature. In comparison with the amine terminated PAMAM dendrimer, we find Rg of G-th generation PETIM dendrimer is nearly equal to that of (G+1)-th generation of PAMAM dendrimer as observed by Maiti et. al. [Macromolecules,38, 979 2005]. We find substantial back folding of the outer sub generations into the interior of the dendrimer. Due to their highly flexible nature of the repeating branch units, the shape of the PETIM dendrimer deviates significantly from the spherical shape and the molecules become more and more spherical as the generation increases. The interior of the dendrimer is quite open with internal cavities available for accommodating guest molecules suggesting using PETIM dendrimer for guest-host applications. We also give a quantitative measure of the number of water molecules present inside the dendrimer.Comment: 33 page

Psycho-social dysfunction: Perceived and enacted stigma among tuberculosis patients registered under Revised National Tuberculosis Control Programme.

Objective: To examine the perceived and enacted stigma experienced by TB patients and the community. Methods: We interviewed 276 TB patients registered for treatment during January-March 2004 in government health facilities of two Tuberculosis Units of south India. Data on perceived and enacted stigma were collected after two months of starting treatment, using a semi-structured interview schedule. In addition, four Focus Group Discussions were conducted among Directly Observed Treatment (DOT) providers and community members. Narrative summaries were also taken down to collect additional qualitative information. Results: Of the 276 patients, 190 (69%) were males. There was no significant difference between the genders in relation to social stigma. Perceived stigma was higher than enacted stigma in both genders and significantly higher among males (Low self esteem p<0.05), change of behavior of community (p<0.05), ashamed to cough in front of others (p<0.05). Conclusion: Considering the social and emotional impact of the disease, it is essential to adopt support strategies to enhance acceptance and for a successful health programme

Tuberculosis awareness among educated public in two cities in Tamil Nadu

A questionnaire on source of information regarding tuberculosis, signs and symptoms, diagnostic methods, treatment duration and personal and community hygiene relating to tuberculosis, was administered to 446 students and employees with an educational status of high school certificate and above. The main source of information were books and magazines and 86% were aware that the Tuberculosis germ was the causative agent. Symptoms of Tuberculosis such as cough (85%) and loss of weight (74%) were well known. Other symptoms suchchest pain (29%), fever (27%) were less known. Sputum examination as a diagnostic tool was known to 68% while 80% knew about radiograph being used to diagnose the disease. Cough as a method of spread was known to 91%. In this questionnaire the duration of treatment was the least known fact. 28% felt that treatment could be stopped if symptoms disappeared. 16% were aware that the method of sputum disposal was by incineration. The implications are discussed

SYNTHESIS AND MOLECULAR DOCKING STUDY OF 2-ARYL/HETEROARYL-6-CHLOROQUINOLINE-4-CARBOXYLIC ACIDS WITH PLASMODIUM LDH RECEPTOR PROTEIN

Objective: Synthesis and in silico molecular docking studies of 2-aryl/heteroaryl-quinoline-4-carboxylic acid derivatives (3a-j) with plasmodium LDH receptor protein.Methods: The 2-aryl/heteroaryl-quinoline-4-carboxylic acids (3a-j) were obtained by Pfitzinger reaction. Ligands (3a-j) interaction with plasmodium LDH receptor protein was studied through molecular docking method.Results: Good yields of 2-aryl/heteroaryl-quinoline-4-carboxylic acid derivatives (3a-j) were obtained by convenient and economical procedure. Their structures were confirmed by 1H NMR, 13C NMR, and MS spectral analysis. The binding site analysis of the synthesized compounds (3a-j) with plasmodium LDH receptor that are responsible for malaria parasite response was evaluated through molecular docking study. The results reveal that the ligand 3d shows maximum of five hydrogen bonding interactions with binding energy -9.05 kcal/mol, shown to be a promising lead molecule to inhibit Plasmodium LDH receptor.Conclusion: The docking studies of newly synthesized 2-aryl/heteroaryl-quinoline-4-carboxylic acids were found to be very useful ligands for antimalarial therapy particularly on Plasmodium LDH protein. However the installation of still many appropriate substitutions on quinoline moiety would lead to identification of novel antimalarial compounds that ascertained via molecular docking is underway in our lab

Frequency-Dependent Squeezing for Advanced LIGO

The first detection of gravitational waves by the Laser Interferometer Gravitational-wave Observatory (LIGO) in 2015 launched the era of gravitational wave astronomy. The quest for gravitational wave signals from objects that are fainter or farther away impels technological advances to realize ever more sensitive detectors. Since 2019, one advanced technique, the injection of squeezed states of light is being used to improve the shot noise limit to the sensitivity of the Advanced LIGO detectors, at frequencies above $\sim 50$ Hz. Below this frequency, quantum back action, in the form of radiation pressure induced motion of the mirrors, degrades the sensitivity. To simultaneously reduce shot noise at high frequencies and quantum radiation pressure noise at low frequencies requires a quantum noise filter cavity with low optical losses to rotate the squeezed quadrature as a function of frequency. We report on the observation of frequency-dependent squeezed quadrature rotation with rotation frequency of 30Hz, using a 16m long filter cavity. A novel control scheme is developed for this frequency-dependent squeezed vacuum source, and the results presented here demonstrate that a low-loss filter cavity can achieve the squeezed quadrature rotation necessary for the next planned upgrade to Advanced LIGO, known as "A+."Comment: 6 pages, 2 figures, to be published in Phys. Rev. Let

GGE biplot analysis to evaluate genotype, environment and their interactions in sorghum multi-location data

Sorghum [Sorghum bicolor (L.) Moench] is a very important crop in the arid and semi-arid tropics of India and African subcontinent. In the process of release of new cultivars using multi-location data major emphasis is being given on the superiority of the new cultivars over the ruling cultivars, while very less importance is being given on the genotype × environment interaction (GEI). In the present study, performance of ten Indian hybrids over 12 locations across the rainy seasons of 2008 and 2009 was investigated using GGE biplot analysis. Location attributed higher proportion of the variation in the data (59.3–89.9%), while genotype contributed only 3.9–16.8% of total variation. Genotype × location interaction contributed 5.8–25.7% of total variation. We could identify superior hybrids for grain yield, fodder yield and for harvest index using biplot graphical approach effectively. Majority of the testing locations were highly correlated. ‘Which-won-where’ study partitioned the testing locations into three mega-environments: first with eight locations with SPH 1606/1609 as the winning genotypes; second mega-environment encompassed three locations with SPH 1596 as the winning genotype, and last mega-environment represented by only one location with SPH 1603 as the winning genotype. This clearly indicates that though the testing is being conducted in many locations, similar conclusions can be drawn from one or two representatives of each mega-environment. We did not observe any correlation of these mega-environments to their geographical locations. Existence of extensive crossover GEI clearly suggests that efforts are necessary to identify location-specific genotypes over multi-year and -location data for release of hybrids and varieties rather focusing on overall performance of the entries

Inheritance of sterility mosaic disease resistance to Bangalore and Patancheru isolates in pigeonpea (Cajanus cajan (L.) Millsp.)

Sterility mosaic disease (SMD), is an important biotic constraint in pigeonpea (Cajanus cajan (L.) Millsp.) in Indian subcontinent. It is caused by a virus and transmitted by eriophyid mites, Aceria cajani Channabasavanna. A comprehensive study of variability in the sterility mosaic pathogen revealed the occurrence of five different isolates in India. Amongst them, three distinct isolates have been characterised, viz., Bangalore, Patancheru and Coimbatore. Studies were conducted at Bangalore and Patancheru to determine the inheritance of resistance to Bangalore and Patancheru isolates of the SMD involving a resistant (ICP 7035) and susceptible (TTB 7) genotypes. Observations in parents, F indicated dominance of susceptibility over resistance. The disease reaction of the individual F 2 plant derived F 3 1 families for Patancheru isolate was controlled by two genes with dominance epistasis and for Bangalore isolate, absence of resistant plants indicate action of two or more genes in controlling resistance to SMD