6,308 research outputs found
A kinematic wave theory of capacity drop
Capacity drop at active bottlenecks is one of the most puzzling traffic
phenomena, but a thorough understanding is practically important for designing
variable speed limit and ramp metering strategies. In this study, we attempt to
develop a simple model of capacity drop within the framework of kinematic wave
theory based on the observation that capacity drop occurs when an upstream
queue forms at an active bottleneck. In addition, we assume that the
fundamental diagrams are continuous in steady states. This assumption is
consistent with observations and can avoid unrealistic infinite characteristic
wave speeds in discontinuous fundamental diagrams. A core component of the new
model is an entropy condition defined by a discontinuous boundary flux
function. For a lane-drop area, we demonstrate that the model is well-defined,
and its Riemann problem can be uniquely solved. We theoretically discuss
traffic stability with this model subject to perturbations in density, upstream
demand, and downstream supply. We clarify that discontinuous flow-density
relations, or so-called "discontinuous" fundamental diagrams, are caused by
incomplete observations of traffic states. Theoretical results are consistent
with observations in the literature and are verified by numerical simulations
and empirical observations. We finally discuss potential applications and
future studies.Comment: 29 pages, 10 figure
Rojak: a study of cultural elements assimilated in selected works of Malaysian contemporary composers (2001-2014)
Malaysian contemporary music, an emerging and highly diverse art form, has gained recognition both in Malaysia and internationally over the last decade. Nevertheless, few studies have been completed and most conclude that there is no common compositional trend. This study, however, highlights that one common trend has emerged since 2000, namely, Malaysian composers have increasingly assimilated cultural elements into their compositions. The resulting works have been metaphorically compared to the national salad dish, rojak, in which all constituent parts are readily identifiable even when mixed together. It is argued that the assimilation of cultures is central to an understanding of Malaysian contemporary music, even though it is not the only compositional approach. Twenty-nine works by five selected Malaysian composers are analysed in this study. The composers are: Kee Yong Chong (b.1971), Chong Lim Ng (b.1972), Tazul Izan Tajuddin (b.1969), Johan Awang Othman (b.1969), and Kah Hoe Yii (b.1970). Musical score analysis, combined with the interpretation of data collected through fieldwork trips to Malaysia and Singapore, reveal the ways these composers have assimilated a myriad of cultural elements, including gamelan, Malay poem pantun, mak yong [Malaysian ancient theatre], wayang kulit [shadow puppet play], Balinese baris dance, the concept of tenunan [weave] and batik, Chinese calligraphy and painting, Chinese orchestra and its instruments, Chinese philosophy, and Islamic, Buddhist and Christian spiritual practices, into their compositions. This study concludes that their use of idiosyncratic approaches is becoming increasingly distinctive to Malaysian compositions and a reflection of the same processes of mixing identifiable ingredients that is found in the national rojak salads.Thesis (Ph.D.) -- University of Adelaide, Elder Conservatorium of Music, 201
A New Look at Physical Layer Security, Caching, and Wireless Energy Harvesting for Heterogeneous Ultra-dense Networks
Heterogeneous ultra-dense networks enable ultra-high data rates and ultra-low
latency through the use of dense sub-6 GHz and millimeter wave (mmWave) small
cells with different antenna configurations. Existing work has widely studied
spectral and energy efficiency in such networks and shown that high spectral
and energy efficiency can be achieved. This article investigates the benefits
of heterogeneous ultra-dense network architecture from the perspectives of
three promising technologies, i.e., physical layer security, caching, and
wireless energy harvesting, and provides enthusiastic outlook towards
application of these technologies in heterogeneous ultra-dense networks. Based
on the rationale of each technology, opportunities and challenges are
identified to advance the research in this emerging network.Comment: Accepted to appear in IEEE Communications Magazin
Origins of Large Voltage Hysteresis in High Energy-Density Metal Fluoride Lithium-Ion Battery Conversion Electrodes
Metal fluoride and oxides can store multiple lithium-ions through conversion
chemistry to enable high energy-density lithium-ion batteries. However, their
practical applications have been hindered by an unusually large voltage
hysteresis between charge and discharge voltage-profiles and the consequent low
energy efficiency (< 80%). The physical origins of such hysteresis are rarely
studied and poorly understood. Here we employ in situ X-ray absorption
spectroscopy (XAS), transmission electron microscopy (TEM),
density-functional-theory (DFT) calculations, and galvanostatic intermittent
titration technique (GITT) to first correlate the voltage profile of iron
fluoride (), a representative conversion electrode material, with
evolution and spatial distribution of intermediate phases in the electrode. The
results reveal that, contrary to conventional belief, the phase evolution in
the electrode is symmetrical during discharge and charge. However, the spatial
evolution of the electrochemically active phases, which is controlled by
reaction kinetics, is different. We further propose that the voltage hysteresis
in the electrode is kinetic in nature. It is the result of Ohmic
voltage drop, reaction overpotential, and different spatial distributions of
electrochemically-active phases (i.e. compositional inhomogeneity). Therefore,
the large hysteresis can be expected to be mitigated by rational design and
optimization of material microstructure and electrode architecture to improve
the energy efficiency of lithium-ion batteries based on conversion chemistry
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Sedimentation of the Lower Cretaceous Xiagou formation and Its Response to Regional Tectonics in the Qingxi Sag, Jiuquan Basin, NW China
Under the constraint of an isochronous sequence stratigraphic framework, sediment infill of the Xiagou Formation reflects the overall control of dynamic tectonic movements and episodic sedimentations in the Qingxi Sag. Structure reactivity during post-depositional processes could cause stratigraphic variations in longitudinal time and lateral space. This study documents sediment infill features and their response to the tectonic evolutions of the Qingxi Sag. The data sets include comparison of cores, well drilling, 3D seismic, inter-well correlation, wave impedance inversion profiles, original strata recovery data, sedimentary fades spatial evolution and their superimposition with paleogeomorphology. The Jiuquan Basin is a Mesozoic-Cenozoic superposition basin comprising an early rifting graben phase and a later compression phase. Since the Early Cretaceous, the basin has undergone four major tectonic episodes: 1) extension during the Early Cretaceous, 2) tectonic inversion caused by northwest-southeast contraction from the Late Cretaceous to the Paleocene, 3) weak extension from the Eocene to the Miocene and 4) contraction from the Miocene to the present. Therefore, the Jiuquan Basin is the product of taphrogenic, collisional and shearing movements. Seismic interpretations of sequence and maximum flooding surface divide the Xiagou Formation into three third order sequences: SQK1g(0), SQK1g(1) and SQK1g(2+3). Five sedimentary facies associations are identified: the shoreland plain, fan delta dominated sedimentary systems, turbidite deposits, shallow lakes and half-deep lake systems. From K1g(0) to K1g(2+3), decreased sandstone percentages in three fan delta areas indicate a continuously transgressive process, which shows the transition from proximal to distal sites in most statistic wells and an obvious decrease of fan delta scales. The northeast-southwest faults control the lakeward distributions of delta fronts and turbidite fans. The correspondence of sedimentary infill and its response to tectonic movements have been demonstrated in the Qingxi Sag. The more active eastern part of the northeastern boundary fault has an important influence on the northeastward migration of depocenters in the Xiagou Formation. The topography developed continuously from K1g(0) to K1g(2+3), but the diminished subsidence indicates the dominant geological process varying from intense fault rifting in an early period to relatively gentle and overall subsidence in a later period during the Early Cretaceous. (C) 2013 Elsevier Ltd. All rights reserved.Key Laboratory of Tectonics and Petroleum Resources, Ministry of Education TPR-2011-09Project of "Double strong effect, driving mechanism and hydrocarbon significance of tectonic activity during depositional period of Dongying Formation in Qikou and Nanpu Sag, Eastern China" 41272122Geological Science
Rapid identification of chloroquine and atovaquone drug resistance in Plasmodium falciparum using high-resolution melt polymerase chain reaction
<p>Abstract</p> <p>Background</p> <p>Drug resistance determination for <it>Plasmodium falciparum </it>infections are important to determining the type of treatment to be given. Besides <it>in vivo </it>experiments, molecular methods, such as sequencing and PCR, are now increasingly being used. Here a cheaper alternative to sequencing or the use of multiplex 5'nuclease PCR assay for detection and differentiation of drug resistance haplotypes for chloroquine and atovaquone using polymerase chain reaction-high resolution melt (PCR-HRM) is reported.</p> <p>Methods</p> <p>Separate PCR-HRM assays were designed for the detection and differentiation of chloroquine and atovaquone drug resistance haplotypes in <it>P. falciparum</it>. PCR was conducted on a thermal cycler and melt curves generated using a LightScanner. These were tested against reference strains of <it>P. falciparum </it>from MR4 as well as 53 local isolates.</p> <p>Results</p> <p>The PCR-HRM assays are able to detect and differentiate between the various haplotypes consistently. These assays can also be used to detect new variants.</p> <p>Conclusions</p> <p>PCR-HRM is an inexpensive option for the determination of drug resistance profile in <it>P. falciparum </it>and will see increasing use as an alternative to sequencing and 5'nuclease PCR assays in reference laboratories or once PCR systems that are able to conduct HRM become commonplace.</p
Relativistic Harmonic Oscillator
We study the semirelativistic Hamiltonian operator composed of the
relativistic kinetic energy and a static harmonic-oscillator potential in three
spatial dimensions and construct, for bound states with vanishing orbital
angular momentum, its eigenfunctions in compact form, i. e., as power series,
with expansion coefficients determined by an explicitly given recurrence
relation. The corresponding eigenvalues are fixed by the requirement of
normalizability of the solutions.Comment: 14 pages, extended discussion of result
Fe3O4/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
Ning Gan1*, Haijuan Jin1*, Tianhua Li1, Lei Zheng21The State Key Laboratory Base of Novel Functional Materials and Preparation Science, Faculty of Material Science and Chemical Engineering, Ningbo University, Ningbo, 2Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People&#39;s Republic of China *Both authors contributed equally to this workBackground: The purpose of this study was to devise a novel electrochemical immunosensor for ultrasensitive detection of alfa-fetoprotein based on Fe3O4/Au nanoparticles as a carrier using a multienzyme amplification strategy.Methods and results: Greatly enhanced sensitivity was achieved using bioconjugates containing horseradish peroxidase (HRP) and a secondary antibody (Ab2) linked to Fe3O4/Au nanoparticles (Fe3O4/Au-HRP-Ab2) at a high HRP/Ab2 ratio. After a sandwich immunoreaction, the Fe3O4/Au-HRP-Ab2 captured on the electrode surface produced an amplified electrocatalytic response by reduction of enzymatically oxidized hydroquinone in the presence of hydrogen peroxide. The high content of HRP in the Fe3O4/Au-HRP-Ab2 could greatly amplify the electrochemical signal. Under optimal conditions, the reduction current increased with increasing alfa-fetoprotein concentration in the sample, and exhibited a dynamic range of 0.005&ndash;10 ng/mL with a detection limit of 3 pg/mL.Conclusion: The amplified immunoassay developed in this work shows good precision, acceptable stability, and reproducibility, and can be used for detection of alfa-fetoprotein in real samples, so provides a potential alternative tool for detection of protein in the laboratory. Furthermore, this immunosensor could be regenerated by simply using an external magnetic field.Keywords: Fe3O4/Au nanoparticles, alfa-fetoprotein, sandwich immunoassay, electrochemical immunosenso
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