Advantage of endoscopic-ultrasound-fine-needle aspiration associated to Sendai clinical guidelines in detecting the malignant risk in patients with undetermined pancreatic cysts: Long-term follow-up

Aims: Contradictory information exists on whether different clinical guidelines are effective in detecting the malignant risk in patients with pancreatic cysts. We have retrospectively evaluated the accuracy and the long-term outcome in patients with pancreatic cysts with a diameter 65 2 cm when indication for surgery was established by clinical evaluation of their malignant risk according to Sendai Clinical Guidelines associated to endoscopic-ultrasoundfine-needle aspiration. Methods: Patients with pancreatic cysts with a diameter 652 cm were evaluated for their potential malignant risk by endoscopic-ultrasound-fine-needle aspiration associated to the clinical evaluation by Sendai Clinical Guidelines. Long-term outcome and comparison in patients survival as well as the accuracy in detecting malignancies were evaluated with the combined clinical and endoscopic evaluation. Results: Two hundred eighteen patients with pancreatic cysts were observed during a 9-year period of the study and 74 of them (33.9%) presenting with a pancreatic cyst 65 2 cm were eligible for the study. Fourteen malignant neoplasms (18.9%) were detected. The accuracy in detecting malignancy of combined clinical and endoscopic evaluation was very high (0.99). The five-year survival rates for patients who underwent surgery with benign and malignant pancreatic cysts and for patients in observational follow-up were similar (70% and 85%). The cohort of patients with malignant pancreatic cysts with ductal adenocarcinoma showed a five-year survival rate of 41%. Conclusion: Endoscopic ultrasound fineneedle aspiration associated to Sendai clinical guidelines showed a high accuracy in detecting malignant risk in patients with pancreatic cysts with a diameter 65 2 cm. allowing appropriate selection for surgical treatment with satisfactory long-term survival

A multipurpose experimental facility for advanced X-ray Spectrometry applications

Ponencia presentada en la European Conference on X-Ray Spectrometry (EXRS). 2014Motivation, Ultra High Vacuum Chamber (UHVC) project: To support/enhance the training of scientists/engineers from developing countries in the operation of synchrotron radiation instrumentation; To provide beam time access for R&D projects and hands-on training in SR-XRS based techniques; To promote networking and knowledge sharing; To increase the quality and the competitiveness of the developing countries to apply beam time proposals at SR facilities; To contribute in the further development of XRS techniques in applications with socioeconomicalrelevance (characterization of energy storage/conversion materials, environmental, biological and biomedical applications)Fil: Leani, Juan José. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina.Fil: Leani, Juan José. Nuclear Science and Instrumentation Laboratory, IAEA Laboratories; Austria.Física Atómica, Molecular y Química (física de átomos y moléculas incluyendo colisión, interacción con radiación, resonancia magnética, Moessbauer Efecto.

Endoscopic ultrasound-guided drainage of pancreatic fluid collections : the impact of evolving experience and new technologies in diagnosis and treatment over the last two decades

Background: Endoscopic ultrasound (EUS)-guided drainage is the preferred approach for drainage of pancreatic fluid collections (PFCs) due to the better experience and significant progress using newer stents and access devices during last decade. This study aimed to evaluate the role of the evolving experience and possible influence of new technological devices on the outcome of patients evaluated for PFCs and submitted to EUS-guided drainage during two different periods: the early period at the beginning of ex- perience when a standardized technique was used and the late period when the increased experience of the operator, combined with different stents quality were introduced in the management of PFCs. Methods: We retrospectively analyzed the clinical data of a cohort of 91 consecutive patients, who underwent EUS-guided drainage of symptomatic PFCs from October 2001 to September 2017. Demographic, therapeutic results, complications, and outcomes were compared between early years\u2019 group (20 01\u201320 08) and late years\u2019 group (2009\u20132017). Results: Endoscopic treatment was successfully achieved in 55.6% (20/36) of patients in the early years\u2019 group, and in 96.4% (53/55) in the late years\u2019 group. Eighteen patients (12 in early years\u2019 and 6 in the late year\u2019s group) required additional open surgery. Procedural complications were observed in 5 patients, 4 in early years\u2019 and 1 in late years\u2019 group. Mortality was registered in two patients (2.2%), one for each group. Conclusions: During our long-term survey using EUS-guided endoscopic drainage of PFCs, significantly better outcomes in term of improved success rate and decrease complications rate were observed during the late period

A new kind of UHV piezotranslator

5nonenoneMazzolini F; Fava C; De Bona F; Sandrin G.; Gambitta AMazzolini, F; Fava, C; DE BONA, Francesco; Sandrin, G.; Gambitta, A

Proposal of a new endoscopic classification of lesions from caustic ingestion

L'endoscopie d'urgence du tractus digestif supérieur (EUTDS) joue un rôle fondamental dans l'évaluation diagnostique des patients ayant ingéré des substances caustiques (IC). L'EUTDS donne une description précise de l'entité et de la topographie des lésions, mais elle devrait donner en plus des indications objectives sur la conduite thérapeutique à mettre en œuvre immédiatement (médicale ou chirurgicale). Le propos de notre étude a été 1-a mise au point d'une classification endoscopique des lésions d'IC dont les caractéristiques les plus importantes sont:―évaluation morphologique directe des lésions (score de 0 à 4