940 research outputs found
In the literature: July 2022.
Targeting HER2-AXL Heterodimerization To Overcome Resistance To HER2 Blockade In Breast Cance
Simulation-Based Inference for Global Health Decisions
The COVID-19 pandemic has highlighted the importance of in-silico
epidemiological modelling in predicting the dynamics of infectious diseases to
inform health policy and decision makers about suitable prevention and
containment strategies. Work in this setting involves solving challenging
inference and control problems in individual-based models of ever increasing
complexity. Here we discuss recent breakthroughs in machine learning,
specifically in simulation-based inference, and explore its potential as a
novel venue for model calibration to support the design and evaluation of
public health interventions. To further stimulate research, we are developing
software interfaces that turn two cornerstone COVID-19 and malaria epidemiology
models COVID-sim, (https://github.com/mrc-ide/covid-sim/) and OpenMalaria
(https://github.com/SwissTPH/openmalaria) into probabilistic programs, enabling
efficient interpretable Bayesian inference within those simulators
Erratum: “Seed layer technique for high quality epitaxial manganite films” [AIP Advances 6, 085109 (2016)]
No abstract available
Spin and Charge Correlations in Quantum Dots: An Exact Solution
The inclusion of charging and spin-exchange interactions within the Universal
Hamiltonian description of quantum dots is challenging as it leads to a
non-Abelian action. Here we present an {\it exact} analytical solution of the
probem, in particular, in the vicinity of the Stoner instabilty point. We
calculate several observables, including the tunneling density of states (TDOS)
and the spin susceptibility. Near the instability point the TDOS exhibits a
non-monotonous behavior as function of the tunneling energy, even at
temperatures higher than the exchange energy. Our approach is generalizable to
a broad set of observables, including the a.c. susceptibility and the
absorption spectrum for anisotropic spin interaction. Our results could be
tested in nearly ferromagnetic materials.Comment: JETPL class, 6 pages, 2 figure
Disorder Induced Quantum Phase Transition in Random-Exchange Spin-1/2 Chains
We investigate the effect of quenched bond-disorder on the anisotropic
spin-1/2 (XXZ) chain as a model for disorder induced quantum phase transitions.
We find non-universal behavior of the average correlation functions for weak
disorder, followed by a quantum phase transition into a strongly disordered
phase with only short-range xy-correlations. We find no evidence for the
universal strong-disorder fixed point predicted by the real-space
renormalization group, suggesting a qualitatively different view of the
relationship between quantum fluctuations and disorder.Comment: 4 pages, 4 postscript figures, needs RevTeX
Axion search with a quantum-limited ferromagnetic haloscope
A ferromagnetic axion haloscope searches for Dark Matter in the form of
axions by exploiting their interaction with electronic spins. It is composed of
an axion-to-electromagnetic field transducer coupled to a sensitive rf
detector. The former is a photon-magnon hybrid system, and the latter is based
on a quantum-limited Josephson parametric amplifier. The hybrid system consists
of ten 2.1 mm diameter YIG spheres coupled to a single microwave cavity mode by
means of a static magnetic field. Our setup is the most sensitive rf
spin-magnetometer ever realized. The minimum detectable field is
T with 9 h integration time, corresponding to a limit on
the axion-electron coupling constant at 95% CL.
The scientific run of our haloscope resulted in the best limit on DM-axions to
electron coupling constant in a frequency span of about 120 MHz, corresponding
to the axion mass range -eV. This is also the first apparatus
to perform an axion mass scanning by changing the static magnetic field.Comment: 4 pages, 4 figure
Searching for galactic axions through magnetized media: QUAX status report
The current status of the QUAX R\&D program is presented. QUAX is a
feasibility study for a detection of axion as dark matter based on the coupling
to the electrons. The relevant signal is a magnetization change of a magnetic
material placed inside a resonant microwave cavity and polarized with a static
magnetic field.Comment: Contributed to the 13th Patras Workshop on Axions, WIMPs and WISPs,
Thessaloniki, May 15 to 19, 201
Ab initio study of canted magnetism of finite atomic chains at surfaces
By using ab initio methods on different levels we study the magnetic ground
state of (finite) atomic wires deposited on metallic surfaces. A
phenomenological model based on symmetry arguments suggests that the
magnetization of a ferromagnetic wire is aligned either normal to the wire and,
generally, tilted with respect to the surface normal or parallel to the wire.
From a first principles point of view, this simple model can be best related
to the so--called magnetic force theorem calculations being often used to
explore magnetic anisotropy energies of bulk and surface systems. The second
theoretical approach we use to search for the canted magnetic ground state is
first principles adiabatic spin dynamics extended to the case of fully
relativistic electron scattering. First, for the case of two adjacent Fe atoms
an a Cu(111) surface we demonstrate that the reduction of the surface symmetry
can indeed lead to canted magnetism. The anisotropy constants and consequently
the ground state magnetization direction are very sensitive to the position of
the dimer with respect to the surface. We also performed calculations for a
seven--atom Co chain placed along a step edge of a Pt(111) surface. As far as
the ground state spin orientation is concerned we obtain excellent agreement
with experiment. Moreover, the magnetic ground state turns out to be slightly
noncollinear.Comment: 8 pages, 5 figures; presented on the International Conference on
Nanospintronics Design and Realizations, Kyoto, Japan, May 2004; to appear in
J. Phys.: Cond. Matte
SOT-MRAM 300mm integration for low power and ultrafast embedded memories
We demonstrate for the first time full-scale integration of top-pinned
perpendicular MTJ on 300 mm wafer using CMOS-compatible processes for
spin-orbit torque (SOT)-MRAM architectures. We show that 62 nm devices with a
W-based SOT underlayer have very large endurance (> 5x10^10), sub-ns switching
time of 210 ps, and operate with power as low as 300 pJ.Comment: presented at VLSI2018 session C8-
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