LLNL NESHAPs 1996 Annual Report

This annual report is prepared pursuant to the National Emissions Standards for Hazardous Air Pollutants (NESHAPs) 40 CFR Part 61, Subpart H; Subpart H governs radionuclide emissions to air from Department of Energy (DOE) facilities. NESHAPs limits the emission of radionuclides to the ambient air from DOE facilities to levels resulting in an annual effective dose equivalent (EDE) of 10 mrem (10 microsieverts) to any member of the public. The EDEs for the Lawrence Livermore National Laboratory (LLNL) site-wide maximally exposed members of the public from 1996 operations were (1) Livermore site: 0. 093 mrem (0.93 microsievert) (52% from point-source emissions, 48% from diffuse-source emissions); (2) Site 300: 0.033 mrem (0.33 microsievert) (99% from point-source, 1% from diffuse-source emissions). The EDEs were generally calculated using the EPA-approved CAP88-PC air-dispersion/dose-assessment model. Site-specific meteorological data, stack flow data, and emissions estimates based on radionuclide inventory data or continuous-monitoring systems data were the specific input to CAP88-PC for each modeled source. 5 figs., 8 tabs

Increased homocysteine plasma levels in breast cancer patients of a Mexican population

Aim: Hyperhomocysteinemia has been associated with different pathologies, including cardiovascular diseases, hypertension, diabetes, and breast cancer (BC). To examine the differences in total homocysteine (tHcy) plasma levels, we compared healthy women to BC patients from a Mexican population. Materials and Methods: The tHcy plasma levels were measured using high-performance liquid chromatography with a fluorescence detector in 89 female controls and 261 BC patients. Results: The observed plasma tHcy levels were significantly higher among the BC patients (11.1019 ± 5.9161 µmol/l) compared to the controls (9.1046 ± 1.3213 µmol/l) (p = 0.002), and these differences were evident when stratified by age (≥ 50 years old), menopause status, overweight and obesity, miscarriages, node metastases, progression, subtype classification (luminal, Her2 and triple negative) and nonresponse to chemotherapy. Conclusions: The tHcy plasma levels could be a good marker for the progression and chemosensitivity of BC in the analyzed sample from a Mexican population. Key Words: plasma levels, homocysteine, HPLC, breast cancer, Mexican population

The σ\sigma pole in J/ψ→ωπ+π−J/\psi \to \omega \pi^+ \pi^-

Using a sample of 58 million $J/\psi$ events recorded in the BESII detector, the decay $J/\psi \to \omega \pi^+ \pi^-$ is studied. There are conspicuous $\omega f_2(1270)$ and $b_1(1235)\pi$ signals. At low $\pi \pi$ mass, a large broad peak due to the $\sigma$ is observed, and its pole position is determined to be $(541 \pm 39)$ - $i$ $(252 \pm 42)$ MeV from the mean of six analyses. The errors are dominated by the systematic errors.Comment: 15 pages, 6 figures, submitted to PL

Reliability, Validity, and Responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO©) Scores in Influenza-Positive Patients

Objectives: To assess the reliability, validity, and responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO©) scores for quantifying the presence and severity of influenza symptoms. Methods: An observational prospective cohort study of adults (≥18 years) with influenza-like illness in the United States, the United Kingdom, Mexico, and South America was conducted. Participants completed the 37-item draft FLU-PRO daily for up to 14 days. Item-level and factor analyses were used to remove items and determine factor structure. Reliability of the final tool was estimated using Cronbach α and intraclass correlation coefficients (2-day reliability). Convergent and known-groups validity and responsiveness were assessed using global assessments of influenza severity and return to usual health. Results: Of the 536 patients enrolled, 221 influenza-positive subjects comprised the analytical sample. The mean age of the patients was 40.7 years, 60.2% were women, and 59.7% were white. The final 32-item measure has six factors/domains (nose, throat, eyes, chest/respiratory, gastrointestinal, and body/systemic), with a higher order factor representing symptom severity overall (comparative fit index = 0.92; root mean square error of approximation = 0.06). Cronbach α was high (total = 0.92; domain range = 0.71–0.87); test-retest reliability (intraclass correlation coefficient, day 1–day 2) was 0.83 for total scores and 0.57 to 0.79 for domains. Day 1 FLU-PRO domain and total scores were moderately to highly correlated (≥0.30) with Patient Global Rating of Flu Severity (except nose and throat). Consistent with known-groups validity, scores differentiated severity groups on the basis of global rating (total: F = 57.2, P < 0.001; domains: F = 8.9–67.5, P < 0.001). Subjects reporting return to usual health showed significantly greater (P < 0.05) FLU-PRO score improvement by day 7 than did those who did not, suggesting score responsiveness. Conclusions: Results suggest that FLU-PRO scores are reliable, valid, and responsive to change in influenza-positive adults

LLNL NESHAPs project 1997 annual report

NESHAP`s limits the emission of radionuclides to the ambient air from DOE facilities to levels resulting in an annual effective dose equivalent (EDE) of 10 mrem (100 ({mu}Sv) to any member of the public The EDEs for the Lawrence Livermore National Laboratory (LLNL) site- wide maximally exposed members of the public from 1997 operations were Livermore site. 0 097 mrem (0 97 {mu}Sv) (80% from point-source emissions), 20% from diffuse-source emissions), Site 300 0 014 mrem (O 14 {mu}Sv) (38% from point-source emissions, 62% from diffuse-source emissions) The EDEs were generally calculated using the EPA-approved CAP88-PC air- dispersion/dose-assessment model Site-specific meteorological data, stack flow data, and emissions estimates based on radionuclide inventory data or continuous-monitoring systems data were the specific input to CAP88-PC for each modeled source

LLNL NESHAPs project 1997 annual report

NESHAP`s limits the emission of radionuclides to the ambient air from DOE facilities to levels resulting in an annual effective dose equivalent (EDE) of 10 mrem (100 ({mu}Sv) to any member of the public The EDEs for the Lawrence Livermore National Laboratory (LLNL) site- wide maximally exposed members of the public from 1997 operations were Livermore site. 0 097 mrem (0 97 {mu}Sv) (80% from point-source emissions), 20% from diffuse-source emissions), Site 300 0 014 mrem (O 14 {mu}Sv) (38% from point-source emissions, 62% from diffuse-source emissions) The EDEs were generally calculated using the EPA-approved CAP88-PC air- dispersion/dose-assessment model Site-specific meteorological data, stack flow data, and emissions estimates based on radionuclide inventory data or continuous-monitoring systems data were the specific input to CAP88-PC for each modeled source

Environmental report 1995. Volume 2

This is Volume 2 of the Lawrence Livermore National Laboratory`s (LLNL`s) annual Environmental Report 1995. This volume is intended to support summary data from Volume 1 and is essentially a detailed data report that provides additional data points, where applicable. Some summary data are also included in Volume 2, and more detailed accounts are given of sample collection and analytical methods. Volume 2 includes information in eight chapters on monitoring of air, air effluent, sewage, surface water, ground water, soil and sediment, vegetation and foodstuff, and environmental radiation, as well as three chapters on ground water protection, compliance self-monitoring and quality assurance

Environmental Report 1995. Volume 1

This report contains the results of Lawrence Livermore National Laboratory`s (LLNL) environmental monitoring and compliance effort and an assessment of the impact of LLNL operations on the environment and the public. This first volume describes LLNL`s environmental impact and compliance activities and features descriptive and explanatory text, summary data tables, and plots showing data trends. The summary data include measures of the center of data, their spread or variability, and their extreme values. Chapters on monitoring air, sewage, surface water, ground water, soil and sediment, vegetation and foodstuff, and environmental radiation are present

LLNL NESHAPs 1995 annual report

This annual report is prepared pursuant to the National Emissions Standards for Hazardous Air Pollutants (NESHAPs) 40 CFR Part 61, Subpart H; Subpart H governs radionuclide emissions to air from Department of Energy (DOE) facilities. NESHAPs limits the emission of radionuclides to the ambient air from DOE facilities to levels resulting in an effective dose equivalent (EDE) of 10 mrem to any member of the public. This document contains the EDEs for the Lawrence Livermore National Laboratory (LLNL) site-wide maximally exposed members of the public from 1995 operations

Environmental Report 1994, Volume No. 1

Lawrence Livermore National Laboratory (LLNL), a U.S. Department of Energy (DOE) facility operated by the University of California, serves as a national resource of scientific, technical, and engineering capability. The Laboratory`s mission focuses on nuclear weapons and national security, and over the years has been broadened to include areas such as strategic defense, energy, the environment, biomedicine, technology transfer, the economy, and education. The Laboratory carries out this multifaceted mission in compliance with local, state, and federal environmental regulatory requirements. It does so with the support of the Environmental Protection Department, which is responsible for environmental monitoring and analysis, hazardous waste management, environmental restoration, and ensuring compliance with environmental laws and regulations. LLNL comprises two sites: the Livermore site and Site 300. The Livermore site occupies an area of 3.28 square kilometers on the eastern edge of Livermore, California. Site 300, LLNL`s experimental testing site, is located 24 kilometers to the east in the Altamont Hills, and occupies an area of 30.3 square kilometers. Environmental monitoring activities are conducted at both sites as well as in surrounding areas. This summary provides an overview of LLNL`s environmental activities in 1994, including radiological and nonradiological sampling and surveillance monitoring, remediation, assessment of radiological releases and doses, and determination of the impact of LLNL operations on the environment and public health