9 research outputs found
Characteristics of study participants.
<p>Data presented as mean (SD) or number (%)</p><p>Characteristics of study participants.</p
Forest plot of odds ratios (95% confidence intervals) for the effect of simvastatin on AMD progression from different models of the analysis.
<p>Forest plot of odds ratios (95% confidence intervals) for the effect of simvastatin on AMD progression from different models of the analysis.</p
Lipid levels at baseline and follow-up by treatment allocation.
<p>*P value from paired samples t-test, comparing baseline and follow-up measurements in each treatment group.</p><p>**P value from independent samples t-test comparing the differences (baseline level minus follow-up level) between the two treatment groups.</p
Logistic regression analysis of simvastatin effect on AMD progression.
<p>*Adjusted for age, sex, smoking, and unilateral advanced AMD.</p
Baseline characteristics of placebo and simvastatin study groups.
<p>Baseline characteristics of placebo and simvastatin study groups.</p
AMD progression by treatment allocation and genotypes of the <i>CFH</i> and <i>APOE</i> genes.
<p>Note: Interactions between genotype and simvastatin were tested in a sequential regression model, with treatment group and genotype entered in the first stage and interaction between these two variables entered in the second stage. Coefficients shown are from stage 1 model for the treatment group and genotype variables and from stage 2 for interactions.</p><p>*Adjusted for age, smoking, sex and unilateral advanced AMD.</p
Macular characteristics used to determine severity in non-advanced age-related macular degeneration.
<p>*Category ‘Number’ is related to drusen only.</p