3 research outputs found
Efficient Energy Transfer (EnT) in Pyrene- and Porphyrin-Based Mixed-Ligand Metal–Organic Frameworks
Designing and synthesizing
the ordered light-harvesting systems,
possessing complementary absorption and energy-transfer process between
the chromophores, are essential steps to accomplish successful mimicking
of the natural photosynthetic systems. Metal–organic frameworks
(MOFs) can be considered as an ideal system to achieve this due to
their highly ordered structure, superior synthetic versatility, and
tailorable functionality. Herein, we have synthesized the new light-harvesting
mixed-ligand MOFs (MLMs, MLM-1–3) via solvothermal reactions
between a Zr<sub>6</sub> cluster and a mixture of appropriate ratio
of 1,3,6,8-tetrakisÂ(<i>p</i>-benzoic acid)Âpyrene and [5,10,15,20-tetrakisÂ(4-carboxy-phenyl)Âporphyrinato]-ZnÂ(II)
ligands. The identical symmetry and connectivity of the two ligands
of the MLMs was the key parameter of successful synthesis as a single
MOF form, and the ample overlap between the emission spectrum of pyrene
and the absorption spectrum of porphyrin provided the ideal platform
to design an efficient-energy transfer (EnT) process within the MLMs.
We obtained the nanoscale maps of the fluorescence intensities and
lifetimes of microsize MLM grains for unambiguous visualization of
EnT phenomena occurring between two ligands in MLMs. Moreover, due
to complementary absorption and energy transfer between the two ligands
in the MLMs, our MLMs performed as superior photoinduced singlet-oxygen
generators, verifying the enhanced light-harvesting properties of
the pyrene- and porphyrin-based MLMs
Self-Assembled Novel BODIPY-Based Palladium Supramolecules and Their Cellular Localization
Four new palladium metal supramolecules
with triangular/square architectures derived from boron dipyrromethane
(BODIPY) ligands were synthesized by self-assembly and fully characterized
by <sup>1</sup>H and <sup>31</sup>P NMR, electrospray ionization mass
spectrometry, and single-crystal X-ray diffraction. These supramolecules
were more cytotoxic to brain cancer (glioblastoma) cells than to normal
lung fibroblasts. Their cytotoxicity to the glioblastoma cells was
higher than that of a benchmark metal-based chemotherapy drug, cisplatin.
The characteristic green fluorescence of the BODIPY ligands in these
supramolecules permitted their intracellular visualization using confocal
microscopy, and the compounds were localized in the cytoplasm and
on the plasma membrane
Self-Assembled Novel BODIPY-Based Palladium Supramolecules and Their Cellular Localization
Four new palladium metal supramolecules
with triangular/square architectures derived from boron dipyrromethane
(BODIPY) ligands were synthesized by self-assembly and fully characterized
by <sup>1</sup>H and <sup>31</sup>P NMR, electrospray ionization mass
spectrometry, and single-crystal X-ray diffraction. These supramolecules
were more cytotoxic to brain cancer (glioblastoma) cells than to normal
lung fibroblasts. Their cytotoxicity to the glioblastoma cells was
higher than that of a benchmark metal-based chemotherapy drug, cisplatin.
The characteristic green fluorescence of the BODIPY ligands in these
supramolecules permitted their intracellular visualization using confocal
microscopy, and the compounds were localized in the cytoplasm and
on the plasma membrane