18 research outputs found
Structural and Biochemical Evaluation of the Interaction of the Phosphatidylinositol 3-Kinase p85a Src Homology 2 Domains with Phosphoinositides and Inositol Polyphosphates
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Archaeological predictive modelling in raised mires – concerns and approaches for their interpretation and future management
No full textWilson's disease: acute and presymptomatic laboratory diagnosis and monitoring
No full textWilson's disease, the most common inherited disorder of copper metabolism, is a recessive genetic condition. The clinical presentation of Wilson's disease is very variable. It is characterised by low serum copper and caeruloplasmin concentrations coupled with the pathological accumulation of copper in the tissues. However, there are diagnostic difficulties and these are discussed. The current value of DNA diagnosis, both in gene tracking in families or as applied to de novo cases, is examined. Wilson's disease can be treated successfully but treatment must be life long. Patients are best treated by specialist centres with experience and expertise in the condition. Key Words: Wilson's disease • copper • diagnosi
Transformed human bronchial epithelial cells (beas-2b) alter the growth and morphology of normal human bronchial epithelial cells in vitro
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