GC-427 Elevating AI Research: Creating a website for Kennesaw State University\u27s AI Lab

The project titled Elevating AI Research: Creating a website for Kennesaw State University\u27s AI Lab is dedicated to developing an HTML5 Content Management System website for Kennesaw State University. This website, AILab.kennesaw.edu, serves as a dedicated platform to showcase lab facilities, ongoing projects, and cutting-edge research, with a focus on promoting global AI research and education. Our target audience encompasses university students, faculty, AI researchers, and organizations with an interest in AI innovation.Preliminary findings support our goal: engaging platforms showcasing AI Lab research effectively.The incorporation of admin access empowers university professors to customize content, thus enhancing adaptability and personalization. These preliminary results underscore the project\u27s promising direction and potential to establish a compelling online presence for the AI Lab at Kennesaw State University, with transformative implications for AI research and education

રાજકોટ રાજ્યનો રાજકીય અને સાંસ્કૃતિક ઇતિહાસઃ ૧૮૬૨ થી ૧૯૪૭

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Structure-activity relationships of fluorene compounds inhibiting HCV variants

Approximately 71 million people suffer from hepatitis C virus (HCV) infection worldwide. Persistent HCV infection causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma, resulting in approximately 400,000 deaths annually. Effective direct-acting antiviral agents (DAAs) have been developed and are currently used for HCV treatment targeting the following three proteins: NS3/4A proteinase that cleaves the HCV polyprotein into various functional proteins, RNA-dependent RNA polymerase (designated as NS5B), and NS5A, which is required for the formation of double membrane vesicles serving as RNA replication organelles. At least one compound inhibiting NS5A is included in current HCV treatment regimens due to the high efficacy and low toxicity of drugs targeting NS5A. Here we report fluorene compounds showing strong inhibitory effects on GT 1b and 3a of HCV. Moreover, some compounds were effective against resistance-associated variants to DAAs. The structure-activity relationships of the compounds were analyzed. Furthermore, we investigated the molecular bases of the inhibitory activities of some compounds by the molecular docking method.11Ysciescopu

Enhancement of the bio-hydrogen production from complex food wastewater using the hematite and nickel oxide nanoparticles

Nickel oxide and hematite nanoparticles were used to enhance bio-hydrogen production from complex wastewater. This study is conducted thoroughly studied in the batch dark fermentation test. During this batch test hematite nanoparticles alone (400 mg/L) showed a significant enhancement of 133 mL/g VSadded and 4.2 mL/h in hydrogen yield and hydrogen production rate respectively, representing a 19% and 27% relative enhancement, respectively, compared to nickel oxide nanoparticles, and therefore corroborate the usefulness of hematite nanoparticles on the hydrogen production process. Furthermore, the novel approach of simultaneous addition of hematite (400 mg/L) and nickel oxide (10 mg/L) nanoparticles gave a hydrogen yield of 139 mL/g VSadded and hydrogen production rate of about and 4.4 mL/h, during a batch test of complex food waste. The potentials of the possible synergy of simultaneous addition of hematite and nickel oxide nanoparticle for an increase in the bio-hydrogen production, representing an enhancement of about 1.7-fold compared to single nanoparticle addition, is fairly demonstrated in the present study, Conclusively, enhanced activity of the enzymes owing to an optimum loading of nanoparticles of nickel and hematite was attributed to the observed relatively maximum increase in hydrogen production rate and hydrogen yield of about 64%, and 69%, respectively, during the batch test

Knowledge, attitude and practices towards COVID-19 among people living with HIV in Pune, India: a cross-sectional study

Background: Studies on knowledge, attitude, and practices (KAP) are important for implementation of interventions. This cross-sectional study was conducted among HIV infected individuals attending antiretroviral therapy (ART) centre at Pune, India, to assess KAP towards COVID-19.Methods: The study conducted between June and December 2020 consisted of twelve, five and seven questions pertaining to knowledge, attitude, and practices respectively towards COVID-19. Frequencies and percentages of correct knowledge, attitude and practices were calculated. Overall knowledge scores were categorized into poor, moderate and good using class width equation.Results: Of the total 1175 participants enrolled, 649 (55.2%) were females. Mean age and CD4count of participants at study entry were 44 years (SD: 9.1) and 637 cells/mm3 (SD: 297) respectively. Overall, 400 (34.0%, 95% CI: 31.33-36.83), 612 (52.1%, 95% CI: 49.18-54.98) and 163 (13.9%, 95% CI: 11.95-15.98) participants had good, moderate and poor knowledge respectively regarding COVID-19. Illiterate participants had six times higher probability of having poor knowledge as compared to their counterparts (OR 5.70, 95% CI: 3.94-8.23; p<0.001). Majority of people living with (PLHIV) had correct attitude towards adherence to government prevention and control measures. Healthy preventive practices of social distancing (99.5%), wearing masks at public places (99.7%) and frequent washing hands with soap and water (98.7%) were followed by PLHIV.Conclusions: PLHIV have average knowledge, correct attitude towards adherence to government prevention and control measures, and appropriate practices towards prevention of COVID-19. Counselling sessions at ART centres should include information for improving knowledge related to COVID-19 especially targeting illiterate individuals.

Current state of awareness and safety practices for ionising radiation risks in orthopaedic doctors in Navi Mumbai: an online survey

Background: Radiographic imaging in orthopaedic surgical centers is becoming more common, posing additional risks to the orthopaedic doctors, who become more exposed to ionising irradiation. As a result, orthopaedic surgeons must have a good understanding of radiation hazards. Despite these issues, many orthopaedic specialists do not get basic radiation safety training. A review of orthopaedic specialists' understanding, awareness, and routine radiation safety practices at an academic hospital in Navi Mumbai. Methods: After institutional ethical approval, a panel of experts created an online survey comprising multiple-choice questions, which was utilized to perform a descriptive research. The questionnaire contained several aspects, each of which assessed orthopaedic understanding, awareness, and practices. The research cohort comprised orthopaedic doctors working through our tertiary medical center and medical college. Results: According to our findings, only 82% of respondents were aware of the radiation dangers associated with fluoroscopy. The use of lead aprons, thyroid shields, goggles, and protective caps is 99%, 42%, 25%, and 25%, respectively. Despite the fact that 60% of respondents were aware of TLD badges. Only 23% of those who operate with inosing radiation use TLD badges. Approximately 61% of respondents were ignorant of intermittent fluoroscopy, and 85% utilized the C-arm tube while the device was active. Conclusions: The vast majority of orthopaedic doctors utilise fluoroscopic imagery in the operating room on a daily basis, but they lack in-depth information and awareness about the radiation security hazards connected with this imaging modality. It is consequently advised that a radiation safety training curriculum be implemented

Preparation and characterization of Fe-doped TiO<SUB>2</SUB> powders for solar light response and photocatalytic applications

Different amounts of Fe-doped TiO2 (with 0.1 to 10 wt.% Fe) powders were prepared at temperatures in the range of 400 and 800 °C following a conventional co-precipitation technique and were thoroughly characterized by means of X-ray diffraction (XRD), Fourier-transform infrared (FT-IR), Fourier-transform Raman (FT-Raman), diffuse reflectance spectroscopy (DRS), BET surface area, zeta potential and flat band potential measurements. Photocatalytic ability of Fe-doped TiO2 powders was evaluated by means of methylene blue (MB) degradation experiments conducted under the irradiation of simulated solar light. Characterization results suggested that as a dopant Fe stabilized TiO2 in the form of anatase phase, reduced its band gap energy and adjusted its flat band potentials in such a way that these powders can be employed for photoelectrolysis of water into hydrogen and oxygen in photoelectrochemical (PEC) cells. The 0.1 wt.% Fe-doped TiO2 exhibited highest activity in the photocatalytic degradation of MB. The kinetic studies revealed that the MB degradation reaction follows the Langmuir-Hinshelwood first order reaction rate

Twelfth rib syndrome: role of intercostal blocks: case series of 10 patients

Twelfth rib syndrome (TRS) is a rare condition that causes severe pain in the loin. It is often misdiagnosed, leading to unnecessary investigations and treatments. Intercostal blocks in the 11th and 12th rib often resolve the pain for these patients. In this research paper, we aim to explore the role of intercostal block in the management of TRS based on our experience with 10 patients. Data of patients who were diagnosed with TRS were studied retrospectively from our hospital records who have been given intercostal block injection from the period of Jan 2022 to August 2023 as an audit.  Four patients underwent intercostal blocks. VAS scores were measured in follow-up for 1 and 3 months. 4 patients were lost to follow up and hence not considered in this study. The male to female ratio was 7:3. There was a statistically significant reduction in VAS score at 1 month and 3 months compared to pre-injection times. Patients who have failed conservative management for TRS can be effectively managed with intercostal block injections

Influence of reaction conditions on the composition of liquid products from two-stage catalytic hydrothermal processing of lignin.

The influence of reaction conditions on the composition of liquid products during two-stage hydrothermal conversion of alkali lignin has been investigated in a batch reactor. Reactions were carried out in the presence of formic acid (FA) and Pt/Al2O3 catalyst. The two different sets of reaction conditions involved alternative reaction times of 1 h and 5 h at 265 °C and 350 °C, respectively. These provided different contributions to reaction severity, which affected the compositions of liquid products. Yields of liquid products reached up to 40 wt% (on lignin feed basis) in the presence of FA under the less severe reaction condition. With 5 h reaction time at 350 °C, alkylphenols, alkylguaiacols and hydrocarbons were the dominant liquid products. However, with 5 h reaction time at 265 °C, phenol and methanol became dominant. The two-stage hydrothermal process led to improved lignin conversion, with the potential to manipulate the liquid product range