SNPs showing significant associations with different IMT measurements.

<p>Chr: chromosome, A1: coded allele, P: p-value for association with IMT, CC-IMT_mean: average IMT of the common carotid in a segment excluding the first cm proximal to the bifurcation, CC-IMT_max: maximum IMT of the common carotid in a segment excluding the first cm proximal to the bifurcation, ICA-IMT_mean: average IMT of the internal carotid, ICA-IMT_max: maximum IMT of the internal carotid, Bif-IMT_mean: average IMT of the bifurcation, Bif-IMT_max: maximum IMT of the bifurcation, IMT_mean: average IMT composite value considering the whole carotid tree derived from the segment-specific measurements, IMT_max: Maximum IMT measure considering the whole carotid tree derived from the segment-specific measurements, IMT_mean-max: average of the IMT_max values for the whole carotid tree derived from the segment-specific measurements. rs4888378 was used as proxy SNP for rs2865531.</p

Information of the 26 lung function-associated SNPs selected in the present study [13], [14], [15], [16].

<p>Columns 1 to 9 refer to frequencies, beta and p values for the association of SNPs with lung function fenotypes as found in the literature. Columns 10 to 15 refer to the frequencies and total sample sizes of the same or proxy-SNPs that were looked up in IMPROVE.</p><p>SNP ID: rs number for the SNPs selected from literature. Chr: chromosome, A1: coded allele, A1 freq: frequency of the coded allele, Measure reported: phenotype for which the SNP reached genome-wide significant association, SE: standard error, P: p-value for association with measure reported, proxy LD: linkage disequilibrium between SNP ID from literature (column 1) and the proxy used for replication in IMPROVE (column 11), proxy SNP: rs number for the proxy SNPs used for replication in IMPROVE, n: number of individuals tested in IMPROVE.</p