4 research outputs found

    Additional file 1: Figure S1. of ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

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    Distribution of ANLN nuclear fraction with regard to tamoxifen treatment. Distribution of ANLN nuclear fraction was analyzed with regard to tamoxifen treatment in cohort II, a randomized prospective tamoxifen trial. The distribution of ANLN nuclear fraction was similar in the treatment and control arms with the majority of tumors expressing less than 25% of ANLN nuclear staining. (PDF 25 kb

    Additional file 5: Figure S5. of ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

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    Association of ANLN expression with senescence. Transient knockdown of ANLN expression induced significant levels of cellular senescence compared to controls in SKBR3 cells up to 5 days after initiation of ANLN depletion. Significant levels of cellular senescence compared to controls were noted in T47D cells 5 days after ANLN siRNA knockdown. Similar, but not significant, result was observed 3 days after knockdown. Scale bars 60 μm. (TIF 14662 kb

    Additional file 5: Figure S1. of A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

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    Comparison of CUBN mRNA and IHC-derived protein expression in normal tissue. mRNA and protein expression levels were indicated as a percentage of the maximum. IHC-derived expression values were assigned numerical values; three for strong, two for moderate and one for weak staining. Staining intensities were averaged over the number of available tissue microarray cores (three cores per tissue type). (TIF 1128 kb
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