Chromatographic analysis of immobilized cefotaxime

The aim of the present work was to widen the application of an in-house developed fast, flexible and sensitive high performance liquid chromatography (HPLC) method to the assessment of cefotaxime sodium from aqueous samples. The method was applied to establish the release profile of cefotaxime sodium immobilised in MCM-41 nanoparticles using pH controlled release in aqueous medium. The analytical method proved to be sensible, repeatable (RSD < 1.5 %) and reproducible (RSD < 1 %) in the concentration range studied (0.01-10 μg•mL-1), limit of detection and limit of quantification were 0.036 and 0.12 μg•mL-1 respectively, suitable for the analysis of release of a single active ingredient, having a short analysis time (10 minutes)

Role of the Electrophysiologist in the Treatment of Tachycardia-Induced Cardiomyopathy

Tachycardia-induced cardiomyopathy is a systolic cardiac dysfunction given by prolonged elevated heart rates in patients with incessant or frequent tachyarrhythmias. Arrhythmias associated with tachycardiomyopathy can be either supraventricular (atrial tachycardia, atrial flutter, atrial fibrillation, AVNRT, permanent junctional reciprocating tachycardia, high rates of atrial pacing) or ventricular (frequent premature ventricular complexes, right ventricular outflow tract tachycardia, LVOT, left ventricular fascicular tachycardia, bundle-branch reentry or high rate of ventricular pacing). Electrophysiological study confirms the clinical diagnosis of tachycardia-induced cardiomyopathy, reveals the arrhythmia mechanism and facilitates catheter ablation that results in complete recovery of ventricular function. This chapter has two parts: 1. Theoretical insight into the pathogenesis of tachycardia-induced cardiomyopathy, clinical manifestations and therapy. 2. Practical issues: we describe our EP lab’s experience on electrophysiological study and ablation in patients with tachycardia-induced cardiomyopathy. We will present five cases of ablation: PVCs >30,000/24 h, antidromic tachycardia, 2:1 atrial flutter, persistent atrial fibrillation and RVOT PVCs with nonsustained VT

Investigation of the corrosion inhibition properties of new phenyl aldehyde organic layers functionalized with different amino alcohols electrodeposited on copper

Phenyl aldehyde layers were formed on copper foils by electro-assisted diazonium reactions and subsequently functionalized with either amino-2-propanol or 2-amino-1-butanol. The anticorrosion properties of the two obtained organic films 2-[(phenylmethylidene)amino]butan-1-ol and (phenylmethylidene)amino-propan-2-ol were evaluated in aerated buffer acetate solution pH $=$ 3.5. The electrochemical corrosion inhibition properties were investigated after different immersion times using electrochemical impedance spectroscopy and potentiodynamic polarization analysis (Tafel). Contact angle measurement confirms the hydrophobic nature of the new organic coatings and layer stability after immersion in buffer. The results showed that both developed layers provided good anticorrosion protection and the highest inhibition was achieved using 2-[(phenylmethylidene)amino]butan-1-ol coating on copper, which makes it a useful device for anticorrosion protection. Moreover, correlations between the molecular structures of the corrosion inhibitors and their protecting efficiencies have been established

Investigation of the corrosion inhibition properties of new phenyl aldehyde organic layers functionalized with different amino alcohols electrodeposited on copper

Phenyl aldehyde layers were formed on copper foils by electro-assisted diazonium reactions and subsequently functionalized with either amino-2-propanol or 2-amino-1-butanol. The anticorrosion properties of the two obtained organic films 2-[(phenylmethylidene)amino]butan-1-ol and (phenylmethylidene)amino-propan-2-ol were evaluated in aerated buffer acetate solution pH $=$ 3.5. The electrochemical corrosion inhibition properties were investigated after different immersion times using electrochemical impedance spectroscopy and potentiodynamic polarization analysis (Tafel). Contact angle measurement confirms the hydrophobic nature of the new organic coatings and layer stability after immersion in buffer. The results showed that both developed layers provided good anticorrosion protection and the highest inhibition was achieved using 2-[(phenylmethylidene)amino]butan-1-ol coating on copper, which makes it a useful device for anticorrosion protection. Moreover, correlations between the molecular structures of the corrosion inhibitors and their protecting efficiencies have been established

ICD Electrograms in Patients with Brugada Syndrome

In patients with Brugada syndrome, implantable cardioverter‐defibrillator (ICD) is the only demonstrated treatment that prevents sudden cardiac death. The progress in ICD technology improved the diagnosis and efficacy of implantable devices in the management and treatment of ventricular tachycardia (VT) and ventricular fibrillation (VF). Recording of electrical events just before and after a delivered or aborted ICD therapy permits a more accurate characterization of the rhythm but also provides information on the electrical events preceding the arrhythmia. This chapter aims to gain insight into the mechanism of initiation and termination of spontaneous VF by analyzing intracardiac electrograms (IEGM) in Brugada patients implanted with ICDs. It has two parts: (1) update on ICD electrograms in Brugada syndrome patients, where we review the medical literature on ICD electrograms and their use for detecting electrical manifestations of Brugada syndrome, and (2) examples of ICD electrograms, from our own database of patients affected by Brugada syndrome

Cardiac Anatomy for the Electrophysiologist with Emphasis on the Left Atrium and Pulmonary Veins

This chapter aims to provide basic anatomical knowledge for the interventional electrophysiologists to understand catheter placement and ablation targets. We begin with the location of the heart inside the mediastinum, position of cardiac chambers, pericardial space and neighboring structures of the heart. We continue with the right atrium and important structures inside it: sinus node, cavotricuspid isthmus, Koch’s triangle and interatrial septum with fossa ovalis. A special part of this chapter is dedicated to the left atrium and pulmonary veins with the venoatrial junction, important structures for catheter ablation of atrial fibrillation. We finish our description with both ventricles with outflow tracts and the coronary venous system

Biosensors Applications on Assessment of Reactive Oxygen Species and Antioxidants

Computer networking & communication

Fourier Transform Infrared Spectroscopy - Useful Analytical Tool for Non-Destructive Analysis

Email: consumer/user guide

Implementing virtual experiments in Sciences education - challenges and experiences achieved in the frame of VccSSe Comenius 2.1. project

AbstractSince the beginning of the 21st Century, massive changes took place in the field of education. New teaching and learning methods based on using modern ICT tools - like virtual experiments, educational video-clips or other multimedia products - have been implemented in the educational process.The paper presents an analysis of the impact produced by the implementation of new virtual experiments designed by 146 teachers who participated to a 40hours training modules “Virtual Instrumentation in Science Education” organized in the frame of Socrates-Comenius 2.1. European project “VccSSe - Virtual Community Collaborating Space for Science Education”. Different aspects and interpretation related to the challenges and difficulties encountered during the implementation process are also included