Heavy Higgs production and decay via e+e−→Z0H0→bbˉZ0Z0e^+e^-\to Z^0 H^0 \to b\bar bZ^0Z^0 and irreducible backgrounds at Next Linear Colliders

The complete matrix element for e^+e^-\ar b\bar bZ^0Z^0 has been computed at tree--level and applied to $Z^0H^0$--production followed by Z^0\ar b\bar b and H^0\ar Z^0Z^0, including all the irreducible background, at Next Linear Colliders. We find that, assuming flavour identification of the $Z^0$--decay products, this channel, together with e^+e^-\ar b\bar bW^+W^- in which Z^0H^0\ar (b\bar b)(W^+W^-), can be important for the study of the parameters of the Standard Model Higgs boson over the heavy mass range 2M_{Z^0}\Ord M_{H^0}\Ord 2{m_t}.Comment: 24 pages, LaTeX (uses Feynman), 7 figures (.ps files or hardcopies of figs.2-7 available upon request

J/ψJ/\psi Gluonic Dissociation Revisited : I. Fugacity, Flux And Formation Time Effects

We revisit the standard treatment [Xu, Kharzeev, Satz and Wang, Phys. Rev. C {\bf 53}, 3051 (1996)] of $J/\psi$ suppression due to gluonic bombardment in an equilibrating quark-gluon plasma. Effects arising from gluon fugacity, relative $g-\psi$ flux, and $\psi$ meson formation time are correctly incorporated in the formulation of the gluon number density, velocity-weighted cross section, and the survival probability. Our new formulae are applied to numerically study the pattern of $J/\psi$ suppression in the central rapidity region at RHIC/LHC energies. The temperature and transverse momentum dependence of our graphs have noticeable differences from those of Xu et al.Comment: 15 pages, 6 figure

J/ψJ/\psi suppression: gluonic dissociation {\em vs.} colour screening

We evaluate the suppression of $J/\psi$ production in an equilibrating quark gluon plasma for two competing mechanisms: Debye screening of colour interaction and dissociation due to energetic gluons. Results are obtained for $S+S$ and $Au+Au$ collisions at RHIC and LHC energies. At RHIC energies the gluonic dissociation of the charmonium is found to be equally important for both the systems while the screening of the interaction plays a significant role only for the larger systems. At LHC energies the Debye mechanism is found to dominate for both the systems. While considering the suppression of directly produced $\Upsilon$ at LHC energies, we find that only the gluonic dissociation mechanism comes into play for the initial conditions taken from the self screened parton cascade model in these studies. Thus we find that a systematic study of quarkonium suppression for systems of varying dimensions can help identify the source and the extent of the suppression.Comment: (revised) 5 pages including 3 figures, discussion expande

Feasibility and outcomes after dose reduction of immunochemotherapy in young adults with Burkitt lymphoma and leukemia: results of the BURKIMAB14 trial

High dose -intensive or infusional intermediate -dose immunochemotherapy is highly effective treatment for Burkitt lymphoma irrespective of human immunodeficiency virus (HIV) infection. However, toxicities of these regimens are relevant, especially in older adults and elderly patients. The prospective multicenter BURKIMAB14 trial included four to six blocks of immunochemotherapy according to stage (localized: 1 and 2 non -bulky; advanced: 2 bulky, 3, 4) and age, with dose reduction in patients >55 years old. Dose -intensity of chemotherapy was reduced in patients 55 years old had a significantly higher treatment -related mortality despite dose reduction of chemotherapy. With a median follow-up of 3.61 years the 4 -year OS probability was 73% (range, 63-81%). Age (55 years) and stage (localized vs. advanced) had prognostic significance. No significant differences in OS were observed in HIV -positive versus HIV -negative patients. The results of BURKIMAB14 are similar to those of other dose -intensive immunochemotherapy trials. Age >55 years and advanced stage, but not HIV infection, were associated with poor survival. Dose reduction of chemotherapy in young adults in CMR is safe and does not impact outcomes (clinicaltrials gov. Identifier: NCT05049473)

Acromegaly and gigantism in the medical literature. Case descriptions in the era before and the early years after the initial publication of Pierre Marie (1886)

In 1886 Pierre Marie used the term “acromegaly” for the first time and gave a full description of the characteristic clinical picture. However several others had already given clear clinical descriptions before him and sometimes had given the disease other names. After 1886, it gradually became clear that pituitary enlargement (caused by a pituitary adenoma) was the cause and not the consequence of acromegaly, as initially thought. Pituitary adenomas could be found in the great majority of cases. It also became clear that acromegaly and gigantism were the same disease but occurring at different stages of life and not different diseases as initially thought. At the end of the 19th and beginning of the 20th century most information was derived from case descriptions and post-mortem examinations of patients with acromegaly or (famous) patients with gigantism. The stage was set for further research into the pathogenesis, diagnosis and therapy of acromegaly and gigantism

Historical Backgrounds of Health Education in the Elementary Schools of the United States of America

Introduction. The relation of physical training to health education. 2. The necessity of tracing the history of physical training and of health education to realize how our modern aims in these two subjects have been brought into such close relationship