43 research outputs found
Structure and function of bacterial Initiation factors
No full textBacteria require three initiation factors, IF1, IF2 and IF3, to start protein synthesis. In the last few years the elucidation of both structural and mechanistic aspects pertaining to these proteins has made substantial progress. In this article we outline the translation initiation process in bacteria and review these recent developments giving a summary of the main features of the structure and function of the initiation factors
Initiation factor IF2 binds to the alpha-sarcin loop and helix 89 of Escherichia coli 23S ribosomal RNA
No full textFrom stand-by to decoding site. Adjustment of the mRNA on the 30S ribosomal subunit under the influence of the initiation factors
No full textPreliminary characterization by X-ray diffraction and Raman spectroscopy of a crystalline complex of Bacillus stearothermophilus initiation factor 2 C-domain and fMet-tRNA(fMet)
No full textTranslational initiation factor IF2 from Bacillus stearothermophilus: a spectroscopic and microcalorimetric study of the C-domain
No full textConformational transition of initiation factor 2 from the GTP- to GDP-bound state visualized on the ribosome
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