9 research outputs found
Practical radiation damage-induced phasing
No full textInternational audienceAlthough crystallographers typically seek to mitigate radiation damage in macromolecular crystals, in some cases, radiation damage to specific atoms can be used to determine phases de novo. This process is called radiation damage-induced phasing or "RIP." Here, we provide a general overview of the method and a practical set of data collection and processing strategies for phasing macromolecular structures using RIP
Structure of a LOV protein in apo-state and implications for construction of LOV-based optical tools
No full textStructural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
No full textConformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity
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