525 research outputs found

    Revised geological maps of Darlington based on new borehole information: explanation and description

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    The geology of the Darlington area has been revised based on the interpretation of new borehole information and a re-examination of archival data. The Permian Zechstein Group has been mapped through the district where it forms a series of easterly-dipping formations. These strata have been folded and an easterly-plunging syncline, faulted on its southern side, is mapped through the town of Darlington. This fold structure is partially modified by the dissolution of gypsum in the sequence resulting in the partial collapse and foundering of the strata. A series of maps is presented showing the revised geology, rockhead, drift thickness and the thickness of the gypsum sequence present at two horizons; the Hartlepool Anhydrite (present in the Edlington Formation) and the Billingham Anhydrite (present in the Roxby Formation). A series of five structure contour maps are presented illustrating the fold and fault structure of the area

    Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries

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    <p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth muscle cell proliferation and migration and neointimal macrophage content, effects associated with the inhibition of MCP-1/CCL2 production. The aim of the current study was to evaluate the efficacy of bindarit on in-stent stenosis in the preclinical porcine coronary stent model.</p> <p><b>Methods and Results:</b> One or 2 bare metal stents (Multi-Link Vision, 3.5 mm) were deployed (1:1.2 oversize ratio) in the coronary arteries of 42 pigs (20 bindarit versus 22 controls). Bindarit (50 mg/kg per day) was administered orally from 2 days before stenting until the time of euthanasia at 7 and 28 days. Bindarit caused a significant reduction in neointimal area (39.4%, P<0.001, n=9 group), neointimal thickness (51%, P<0.001), stenosis area (37%, P<0.001), and inflammatory score (40%, P<0.001) compared with control animals, whereas there was no significant difference in the injury score between the 2 groups. Moreover, treatment with bindarit significantly reduced the number of proliferating cells (by 45%, P<0.05; n=6 group) and monocyte/macrophage content (by 55%, P<0.01; n=5–6 group) in stented arteries at day 7 and 28, respectively. These effects were associated with a significant (P<0.05) reduction of MCP-1 plasma levels at day 28. In vitro data showed that bindarit (10–300 micromol/L) reduced tumor necrosis factor-alpha (50 ng/mL)–induced pig coronary artery smooth muscle cell proliferation and inhibited MCP-1 production.</p> <p><b>Conclusion:</b> Our results show the efficacy of bindarit in the prevention of porcine in-stent stenosis and support further investigation for clinical application of this compound.</p&gt

    Kondo Effect of Quantum Dots in the Quantum Hall Regime

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    Quantum dots in the quantum Hall regime can have pairs of single Slater determinant states that are degenerate in energy. We argue that these pairs of many body states may give rise to a Kondo effect which can be mapped into an ordinary Kondo effect in a fictitious magnetic field. We report on several properties of this Kondo effect using scaling and numerical renormalization group analysis. We suggest an experiment to investigate this Kondo effect.Comment: To appear in Phys. Rev. B (5 pages, 4 figures); references added; several changes in tex

    Relativistic corrections in magnetic systems

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    We present a weak-relativistic limit comparison between the Kohn-Sham-Dirac equation and its approximate form containing the exchange coupling, which is used in almost all relativistic codes of density-functional theory. For these two descriptions, an exact expression of the Dirac Green's function in terms of the non-relativistic Green's function is first derived and then used to calculate the effective Hamiltonian, i.e., Pauli Hamiltonian, and effective velocity operator in the weak-relativistic limit. We point out that, besides neglecting orbital magnetism effects, the approximate Kohn-Sham-Dirac equation also gives relativistic corrections which differ from those of the exact Kohn-Sham-Dirac equation. These differences have quite serious consequences: in particular, the magnetocrystalline anisotropy of an uniaxial ferromagnet and the anisotropic magnetoresistance of a cubic ferromagnet are found from the approximate Kohn-Sham-Dirac equation to be of order 1/c21/c^2, whereas the correct results obtained from the exact Kohn-Sham-Dirac equation are of order 1/c41/c^4 . We give a qualitative estimate of the order of magnitude of these spurious terms

    New exact solution of Dirac-Coulomb equation with exact boundary condition

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    It usually writes the boundary condition of the wave equation in the Coulomb field as a rough form without considering the size of the atomic nucleus. The rough expression brings on that the solutions of the Klein-Gordon equation and the Dirac equation with the Coulomb potential are divergent at the origin of the coordinates, also the virtual energies, when the nuclear charges number Z > 137, meaning the original solutions do not satisfy the conditions for determining solution. Any divergences of the wave functions also imply that the probability density of the meson or the electron would rapidly increase when they are closing to the atomic nucleus. What it predicts is not a truth that the atom in ground state would rapidly collapse to the neutron-like. We consider that the atomic nucleus has definite radius and write the exact boundary condition for the hydrogen and hydrogen-like atom, then newly solve the radial Dirac-Coulomb equation and obtain a new exact solution without any mathematical and physical difficulties. Unexpectedly, the K value constructed by Dirac is naturally written in the barrier width or the equivalent radius of the atomic nucleus in solving the Dirac equation with the exact boundary condition, and it is independent of the quantum energy. Without any divergent wave function and the virtual energies, we obtain a new formula of the energy levels that is different from the Dirac formula of the energy levels in the Coulomb field.Comment: 12 pages,no figure

    Quantum trajectory approach to stochastically-induced quantum interference effects in coherently-driven two-level atoms

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    Stochastic perturbation of two-level atoms strongly driven by a coherent light field is analyzed by the quantum trajectory method. A new method is developed for calculating the resonance fluorescence spectra from numerical simulations. It is shown that in the case of dominant incoherent perturbation, the stochastic noise can unexpectedly create phase correlation between the neighboring atomic dressed states. This phase correlation is responsible for quantum interference between the related transitions resulting in anomalous modifications of the resonance fluorescence spectra.Comment: paper accepted for publicatio

    Cosmic Density Perturbations from Late-Decaying Scalar Condensations

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    We study the cosmic density perturbations induced from fluctuation of the amplitude of late-decaying scalar condensations (called \phi) in the scenario where the scalar field \phi once dominates the universe. In such a scenario, the cosmic microwave background (CMB) radiation originates to decay products of the scalar condensation and hence its anisotropy is affected by the fluctuation of \phi. It is shown that the present cosmic density perturbations can be dominantly induced from the primordial fluctuation of \phi, not from the fluctuation of the inflaton field. This scenario may change constraints on the source of the density perturbations, like inflation. In addition, a correlated mixture of adiabatic and isocurvature perturbations may arise in such a scenario; possible signals in the CMB power spectrum are discussed. We also show that the simplest scenario of generating the cosmic density perturbations only from the primordial fluctuation of \phi (i.e., so-called ``curvaton'' scenario) is severely constrained by the current measurements of the CMB angular power spectrum if correlated mixture of the adiabatic and isocurvature perturbations are generated.Comment: 31pages, 14figure

    The Primordial Perturbation Spectrum from Various Expanding and Contracting Phases

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    In this paper, focusing on the case of single scalar field, we discuss various expanding and contracting phases generating primordial perturbations, and study the relation between the primordial perturbation spectrum from these phases and the parameter w of state equation in details. Furthermore, we offer an interesting classification for the primordial perturbation spectrum from various phases, which may have important implications for building an early universe scenario embedded in possible high energy theories.Comment: 5 pages, 3 eps figure
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