A human operator simulator model of the NASA Terminal Configured Vehicle (TCV)

A generic operator model called HOS was used to simulate the behavior and performance of a pilot flying a transport airplane during instrument approach and landing operations in order to demonstrate the applicability of the model to problems associated with interfacing a crew with a flight system. The model which was installed and operated on NASA Langley's central computing system is described. Preliminary results of its application to an investigation of an innovative display system under development in Langley's terminal configured vehicle program are considered

Computational Methods and Results for Structured Multiscale Models of Tumor Invasion

We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss the scientific-computing methodology used to solve the model equations. The models and methodology presented in this paper form the basis for developing and treating increasingly complex, mechanistic models of tumor invasion that will be more predictive and less phenomenological. Because many of the features of the cancer models, such as taxis, aging and growth, are seen in other biological systems, the models and methods discussed here also provide a template for handling a broader range of biological problems

Crop Flexibility in Dryland Corn and Soybeans Using Predicted Yields and Prices

Crop Production/Industries,

The design and implementation of the Technical Facilities Controller (TFC) for the Goldstone deep space communications complex

The Technical Facilities Controller is a microprocessor-based energy management system that is to be implemented in the Deep Space Network facilities. This system is used in conjunction with facilities equipment at each of the complexes in the operation and maintenance of air-conditioning equipment, power generation equipment, power distribution equipment, and other primary facilities equipment. The implementation of the Technical Facilities Controller was completed at the Goldstone Deep Space Communications Complex and is now operational. The installation completed at the Goldstone Complex is described and the utilization of the Technical Facilities Controller is evaluated. The findings will be used in the decision to implement a similar system at the overseas complexes at Canberra, Australia, and Madrid, Spain

Formation and Collapse of Nonaxisymmetric Protostellar Cores in Planar Magnetic Interstellar Clouds: Formulation of the Problem and Linear Analysis

We formulate the problem of the formation and collapse of nonaxisymmetric protostellar cores in weakly ionized, self-gravitating, magnetic molecular clouds. In our formulation, molecular clouds are approximated as isothermal, thin (but with finite thickness) sheets. We present the governing dynamical equations for the multifluid system of neutral gas and ions, including ambipolar diffusion, and also a self-consistent treatment of thermal pressure, gravitational, and magnetic (pressure and tension) forces. The dimensionless free parameters characterizing model clouds are discussed. The response of cloud models to linear perturbations is also examined, with particular emphasis on length and time scales for the growth of gravitational instability in magnetically subcritical and supercritical clouds. We investigate their dependence on a cloud's initial mass-to-magnetic-flux ratio (normalized to the critical value for collapse), the dimensionless initial neutral-ion collision time, and also the relative external pressure exerted on a model cloud. Among our results, we find that nearly-critical model clouds have significantly larger characteristic instability lengthscales than do more distinctly sub- or supercritical models. Another result is that the effect of a greater external pressure is to reduce the critical lengthscale for instability. Numerical simulations showing the evolution of model clouds during the linear regime of evolution are also presented, and compared to the results of the dispersion analysis. They are found to be in agreement with the dispersion results, and confirm the dependence of the characteristic length and time scales on parameters such as the initial mass-to-flux ratio and relative external pressure.Comment: 30 pages, 7 figures Accepted by Ap

Orthogonal, metal-free surface modification by strain-promoted azide–alkyne and nitrile oxide–alkene/alkyne cycloadditions

In this article we present a fast and efficient methodology for biochemical surface patterning under extremely mild conditions. Micropatterned azide/benzaldoxime-surfaces were prepared by microcontact printing of a heterobifunctional cyclooctyne oxime linker on azide-terminated self-assembled monolayers (SAMs). Strain-promoted azide–alkyne cycloaddition (SPAAC) in combination with microcontact printing allows fast and effective surface patterning. The resulting bifunctional azide/oxime substrates could successfully be used for metal-free, orthogonal immobilization of various biomolecules by 1,3-dipolar cycloadditions at room temperature. Azide-decorated areas were modified by reaction with a cyclooctyne-conjugate using SPAAC, while benzaldoxime-decorated areas were activated by in situ oxidation to the reactive nitrile oxides and subsequent nitrile oxide cycloaddition with alkene- and alkyne-functionalized bioconjugates. In addition, orthogonal double immobilization was achieved by consecutive and independent SPAAC and nitrile oxide cycloadditions

Anomalous Scaling and Solitary Waves in Systems with Non-Linear Diffusion

We study a non-linear convective-diffusive equation, local in space and time, which has its background in the dynamics of the thickness of a wetting film. The presence of a non-linear diffusion predicts the existence of fronts as well as shock fronts. Despite the absence of memory effects, solutions in the case of pure non-linear diffusion exhibit an anomalous sub-diffusive scaling. Due to a balance between non-linear diffusion and convection we, in particular, show that solitary waves appear. For large times they merge into a single solitary wave exhibiting a topological stability. Even though our results concern a specific equation, numerical simulations supports the view that anomalous diffusion and the solitary waves disclosed will be general features in such non-linear convective-diffusive dynamics.Comment: Corrected typos, added 3 references and 2 figure

Absorption and Backscattering in the Beaufort and Chukchi Seas

Bio-optical observations were made during August 2000 in the Beaufort and Chukchi Seas. Chlorophyll a concentration (Chl) ranged from 0.068 to 18.5 mg chl m-3. Both total particulate and phytoplankton absorption at 443 nm were closely correlated with chlorophyll concentration. Linear spectral relationships were observed for phytoplankton absorption. The chlorophyll-specific absorption of phytoplankton at 443 nm was nearly constant at 0.013 m2 (mg chl)-1, but particulate absorption due to nonpigmented particulates at 443 nm was highly variable. There was no strong correlation between chlorophyll concentration and absorption by soluble materials or nonpigmented particulates. Absorption, scattering, and attenuation all show strong first-order spectral relationships. Robust relationships between backscattering and chlorophyll and backscattering and remote sensing reflectance were evident. These relationships can be used to construct absorption-based algorithms to retrieve various optical constituents

Characterization of slow and fast phase nystagmus

A current literature review of the analog and digital process of vestibular and optical kinetic nystagmus reveals little agreement in the methods used by various labs. The strategies for detection of saccade (fast phase velocity component of nystagmus) vary between labs, and most of the process have not been evaluated and validated with a standard database. A survey was made of major vestibular labs in the U.S. that perform computer analyses of vestibular and optokinetic reflexes to stimuli, and a baseline was established from which to standardize data acquisition and analysis programs. The concept of an Error Index was employed as the criterium for evaluating the performance of the vestibular analysis software programs. The performance criterium is based on the detection of saccades and is the average of the percentages of missed detections and false detections. Evaluation of the programs produced results for lateral gaze with saccadic amplitude of one, two, three, five, and ten degrees with various signal-to-noise ratios. In addition, results were obtained for sinusoidal pursuit of 0.05, 0.10, and 0.50 Hz with saccades from one to ten degrees at various signal-to-noise ratios. Selection of the best program was made from the performance in the lateral gaze with three degrees of saccadic amplitude and in the 0.10 Hz sinusoid with three degrees of saccadic amplitude