Nasal Cytology: A Easy Diagnostic Tool in Precision Medicine for Inflammation in Epithelial Barrier Damage in the Nose. A Perspective Mini Review

Nasal cytology is a diagnostic tool that can be used in precision rhinology medicine. Particularly in non-allergic rhinitis and chronic rhinosinusitis forms it can be useful to evaluate biomarkers of both surgical or biological therapy and especially in the follow-up it must be used to predict the prognostic index of recurrence of nasal polyposis. All inflammatory cytokines are also linked to the presence of cells such as eosinophils and mastcells and nasal cytology is a non-invasive and repeatable method to assess the situation in real life

Risk stratification on 206 patients with acute coronary syndrome at Rome Policlinico Umberto I Emergency Department

Objectives. The objective of this study on patients with suspected Acute Coronary Disease (ACS) was to verify with the risk stratification any differences between patients in which the AHA/ACC guidelines were not systematically applied and the same patients in which, retrospectively, the AHA/ACC guidelines were adhered to. Materials and Methods. Retrospective examination was carried out in our Emergency Department at Rome Policlinico Umberto I on 206 patients (age range 21-88, median age 56.6 +/- 18.9 years) (54.3% males) with symptoms compatible with ACS. All the patients underwent "triage" using code green or code yellow and were sub-divided into 7 subgroups based on degree of risk for death or non-fatal myocardial infarction (MI) at 30 days, (labelled A to G, with A representing highest risk and G the least at-risk) in accordance with the ACC/AHA guidelines. Each patient was then examined for: final outcome, admittance and discharge from hospital, refusal of admittance, death. Results. Of the 206 patients, 48 were judged improperly (23.3%) Of these, 13 were assigned code green rather than code yellow and 11 were assigned code yellow instead of code green. By risk stratification in accordance with the AHA/ACC guidelines, 128 patients (62.1%) belonging to subgroups A,B,C and D should have required hospitalization. Seventy eight patients belonging to subgroups E,F and G should have been sent for observation at the Chest Pain Unit ( CPU), 54 from this group would have been potentially discharged after 6-12 hours of negative clinical observation. Actually, hospitalization was requested for 132 patients (64%) of whom 78 accepted, 50 declined and 4 were deceased before admission; 74 patients (35.9%) were discharged after brief observation. Risk stratification for 30 day mortality or non fatal MI emphasizes that 8 of the patients hospitalized should have been treated at the CPU (unwarranted hospitalization). Twenty four of the 50 patients who declined hospitalization should have benefited by brief observation at the Chest pain Unit. Twenty eight of the 78 patients examined in the Emergency Department and later discharged should have been hospitalized (wrong discharge). Conclusions. This study, even if limited by time restriction, provides enough evidence in support of the effectiveness of the ACC/AHA guidelines to determine subgroups and to correctly determine groups according to level of risk, thus limiting unwarranted hospitalizations and wrong discharges. Clin Ter 2009; 160(5):351-35

HOW TO MANAGE ORGANIZATIONAL IDENTITY WITH WORDS” : APPLYING PSYCHOLINGUISTICS TO ORGANIZATIONAL STUDIES

In recent years, the body of theory on organizational discourse has significantly grown, forming a specific field and contributing to the elaboration of a broader organization and management theory. Studying organizational discourse with an applied-psycholinguistic perspective provides important insights into organizational processes of management, thus reconciling hard (system, structure and staff) with soft factors (skills, strategy and style). These factors concretely construct organizational identity, and when aligned, allow an excellent performance. In this vein, the aim of this study is to investigate how organizational discourse can contribute to shape and reinforce organizational identity, especially in times of change and economical crisis. The context of the study was a medium-sized enterprise, a Publishing House located in the South of Italy, whose workforce was up to 130 employees. In order to capture a “privileged” point of view, only workers from the top and middle management were involved, namely the entrepreneur, 5 staff area managers and 6 supervisors. Individual in-depth interviews were conducted to explore participants’ perception of : a) organizational plant and management style ; b) Human Resource Management practices ; c) salaries policies ; d) career development chances ; e) organizational climate ; f) communication, vision and mission. The discursive data collected were elaborated through Diatextual Analysis, a method within Discourse Analysis which specifically addresses the nexus between interlocutors, texts and contexts of talk. Finally, Greimas, & Courtes’ (1979) semiotic square was adopted to frame the identity profiles that came out of the discursive analysis. Results showed that participants differently shaped their organizational belonging in discourse. Four main discursive positionings (the idealist, the critical, the formal and the hopeless) accounted for the complexity of the sense making processes that actually govern person/organization relationships

Syncope caused by iatrogenic hyperkalemia sincope da iperpotassiemia iatrogena

Symptomatic bradycardia in the emergency department may have several causes (excessive vagal tone, drug toxicity, acute myocardial ischemia, sick sinus syndrome, heart block, and electrolyte imbalance); among these, hyperkalemia may develop as a complication of chronic medical treatment with angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers, and must be considered in the early approach to the bradyarrhythmic patient with possible electrocardiographic signs of hyperkalemia. We report a case of an 87-year-old woman with a clinical history of chronic angiotensin-receptor blocker consumption that led her to dangerous bradyarrhythmia, cardiogenic syncope, and risk of sudden cardiac death

The rhetoric of conflict inside and outside the stadium: The case study of an Italian Football Cheer Group.

Since ancient times, sports have played the role of transposing, on a symbolic level, the aggressive behaviors that are built into human sociality. Mostly in their team manifestations, sporting events represent a so-called tame war. The main aim of this study is to show how the cultural psychology of sport might contribute to an understanding of the sense-making dynamics active in human infighting, though conditioned to a sublimated and ritualized acceptability

Datasets for genetic diversity assessment in a collection of wild and cultivated pomegranates (Punica granatum L.) by microsatellite markers

Data described in this article refer to molecular charac-terization and assessment of genetic diversity within a wide collection of pomegranate genotypes including both selections and cultivars from different geographical ori-gin/disseminations by using microsatellite (SSR, Simple Se-quence Repeats) markers. Supplied datasets refer to a set of 63 genotypes including 55 accessions (landraces) from Italy, Turkmenistan, Japan, and USA and 8 cultivars from Is-rael, established at the pomegranate repository of the Fruit Tree Unit of the Department of Soil, Plant and Food Science at University of Bari "Aldo Moro", Italy. Pomegranate acces-sions differed for end-use purpose (edible, ornamental) and some morpho-pomological traits including juice taste, inner tegmen hardness, and skin/seed color. Molecular data were opportunely employed to build a similarity matrix to estab-lish phylogenetic relationships (genetic similarity and dis-tances) among pomegranate accessions and compare genetic clustering to morpho-pomological classification.The present data article provides detailed information and methodological protocols on SSR markers, PCR amplification and banding profiling aimed to molecular characterization of pomegranate collection. This latter was conducted by am-plifying a set of informative polymorphic SSR markers on the genomic DNA of each pomegranate accession, and then comparing the different molecular profiles by capillary elec-trophoresis. The banding patterns obtained from microsatel-lite markers were used to build a binary matrix containing the scores for each individual SSR fragment, which was trans-formed into a similarity matrix and finally used for clus-ter analysis and dendrogram building based on the UPGMA algorithm. This paper supplies data potentially useful for the identification of polymorphic markers suitable for vari-etal identification and traceability, or discrimination between tightly related pomegranate accessions with very high mor-phological similarity and/or geographical identity. Data described in this paper support the published original research article titled "Exploiting DNA-based molecular tools to assess genetic diversity in pomegranate (Punica granatum L.) selections and cultivars" [1].& COPY; 2023 The Author(s). Published by Elsevier Inc.This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/

Dataset from RNAseq analysis of bud differentiation in Ficus carica

The presented data regards the transcriptome profiling and differential analysis with RNA-Seq approach with the following goals: de novo transcriptome assembly and genome an-notation of Ficus carica and the differential expression analysis of parthenocarpic and non-partenocarpic varieties in or-der to identify candidate genes for the production of seed-less fig. Two fig varieties Dottato and Petrelli and the caprifig were grown at the fig repository at the 'P. Martucci' experimental station in Valenzano (Bari) of University of Bari 'Aldo Moro'.The data included: RNA-seq data obtained from fruits of parthenocarpic and non-parthenocarpic varieties, gene expression in the different genetic materials; genes up and down regulated.The data in this article support information presented in the research article "I. Marcotuli, A. Mazzeo, P. Colasuonno, R. Terzano, D. Nigro, C. Porfido, A. Tarantino, R. Aiese Cigliano, W. Sanseverino, A. Gadaleta, G. Ferrara, Fruit Development in Ficus carica L.: Morphological and Genetic Approaches to Fig Buds for an Evolution From Monoecy Toward Dioecy. Front. Plant Sci.(2020) 11:1208. doi: 10.3389/fpls.2020.01208Published by Elsevier Inc.This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/

Optimization of an In Vitro Embryo Rescue Protocol for Breeding Seedless Table Grapes (Vitis vinifera L.) in Italy

Conventional crossing of stenospermocarpic grapes for the obtainment of seedless cultivars presents some technical constraints causing embryo abortion in the early berry developmental stages. Embryo rescue technique partially overcomes these limitations, but the obtainment of viable plantlets relies on the optimization of several genetic and methodological issues. This work aimed to regenerate viable plants from immature ovules of stenospermocarpic table grape hybrids by applying a three-step in vitro culture protocol consisting of embryo development, embryo germination-rooting, and plantlet formation. The influence of parental genotypes (six “seedless × seedless” crosses), ovule sampling time (30, 40, 50 days after pollination (DAP)), and extent of embryo germination induction (4, 6, 8 weeks) was assessed on ovule fertilization, embryo development and germination, rooting, and plantlet formation to establish the best rescue time for each combination hybrid. Our optimized protocol included immature ovule isolation for 40 DAP and embryo germination induction for 8 weeks. As for genotypes, the most efficient embryo germination was recovered from hybrids of Thompson, Superior, and Regal cultivars, whereas the highest percentage of viable plants was derived from 50-DAP ovules of Luisa × Thompson progeny. Such an optimized protocol could be useful to maximize the efficiency of future breeding programs for grape seedlessness