162 research outputs found
TORT AND EVIDENCE LAWβA SPHINX WITHOUT A SECRET: THE COLLATERAL SOURCE RULE AND MANDATORY HEALTH INSURANCE IN MASSACHUSETTS
This Note argues that in the Commonwealth of Massachusetts the collateral source rule, as applied to health insurance reimbursement, is outdated and is more harmful than beneficial. Part I provides an overview of the notion of compensation in negligence cases and explains the origins and purpose of the collateral source rule. Part II discusses the reasons for the discrepancy between medical bills and insurance write-offs, and their application in Law v. Griffith. Part III touches upon the current tendency toward abrogation of the collateral source rule in various other states. Part IV discusses what makes Massachusetts unique with regard to health insurance. Part V analyzes the shortcomings of the collateral source rule. The Author proposes that the state legislature abrogate the rule as applied to medical payments by health insurance companies, and make such evidence available at trial
TORT AND EVIDENCE LAWβA SPHINX WITHOUT A SECRET: THE COLLATERAL SOURCE RULE AND MANDATORY HEALTH INSURANCE IN MASSACHUSETTS
This Note argues that in the Commonwealth of Massachusetts the collateral source rule, as applied to health insurance reimbursement, is outdated and is more harmful than beneficial. Part I provides an overview of the notion of compensation in negligence cases and explains the origins and purpose of the collateral source rule. Part II discusses the reasons for the discrepancy between medical bills and insurance write-offs, and their application in Law v. Griffith. Part III touches upon the current tendency toward abrogation of the collateral source rule in various other states. Part IV discusses what makes Massachusetts unique with regard to health insurance. Part V analyzes the shortcomings of the collateral source rule. The Author proposes that the state legislature abrogate the rule as applied to medical payments by health insurance companies, and make such evidence available at trial
Periodontal splinting β an adjunct to periodontal therapy
Progressive loss of clinical level of attachment and bone destruction,Β which often are result of spent periodontal disease,Β inevitably leadΒ to increased mobility of the teeth.Β Other causes of tooth mobility are occlusion trauma, atypical root system, iatrogenic shortened roots after an apical osteotomy, excessive strain during orthodontic treatment and root resorption.Β Increased tooth mobility adversely affects the patient's function, aesthetics and comfort.Β Splints are used to overcome these problems
Application of autogenous platelet-rich plasma in periodontology
INTRODUCTION:Autogenous platelet-rich plasma (PRP) is a platelet-rich substance obtained after specific processing of peripheral blood.AIM:The purpose of the present study is to describe and examine the autogenous platelet-rich plasma and its application in periodontology.DISCUSSION:In the last decade, PRP has gained wide popularity and is used in a variety of fields of medicine. The implementation of PRP is basically a regenerative procedure using an autogenous graft. Therefore, it is believed that there is no danger of genetic interference, sensitization, or any kind of disease transmission. Platelet-rich plasma therapy is a safe and effective option with no known risks or side effects. In the last decade or two, the amount of published studies focused on the joined use of barrier membranes and bone repair materials with PRP has increased. One of the main benefits of using PRP to administer damaged tissues is that it activates and releases growth factors, which can enhance collagen and elastin formation by fibroblasts, boost blood supply and metabolism in the affected area, as well as help promote angiogenesis (the formation of new blood vessels). In this way, PRP therapy can effectively restore lost tissue.CONCLUSION:The presented study shows that the implementation of autogenous PRP is an innovative method for periodontal regenerative therapy based on the fact that regenerative therapy methods show different success rates and different long-term results, depending on the materials that are used
Thermo-Fluid Effects Associated with Modelling Subscale Automotive Heat Exchangers
Automotive components are tested extensively in wind tunnels by automotive manufacturers
and race teams. This is usually achieved using an accurate scale model
representation of the component within the wind tunnel.
Automotive heat exchangers, however, are comprised of numerous intricate geometries
and are therefore impractical to produce at model scale. Instead they are
simply modelled as pressure drops, achieved using a thin mesh or honeycomb of
known porosity. Most commercial computational fluid dynamics solvers ignore the
geometry of the heat exchanger and instead model it as a discontinuity with a known
pressure drop and heat transfer.
The pressure drop across an automotive heat exchanger, however, was found to
vary with both the coolant temperature and the angle of inclination of the heat
exchanger. This thesis initially presents a relationship between the pressure drop
coefficient and the inclination angle for varying media porosities. Mathematical
relationships for inclination angles of 0Β°, 15Β°, 30Β° and 45Β°. were derived relating
this pressure drop coefficient to the porosity of the media. Weighted least squares
is proposed over ordinary least squares when obtaining the Forchheimer equation
coefficients from experimental measurements.
Investigation extends into the thermo-fluid effects on a full scale automotive heat
exchanger when inclined at 0 Β°, 15Β°, 30Β° and 45Β°. It was found, depending on the
angle, that there was a difference in the pressure drop of up to 10% between the
unheated and heated (100 C) heat exchanger. Based on the proposed mathematical
relationship, this correlated to a 4% decrease in porosity in order to accurately model
the automotive heat exchanger at subscale.
The thesis concludes with experimental and numerical investigation into the heat
transfer on a hydrodynamically and thermally developing ow within a radiator
channel. Laser doppler anemometry measurements recorded a 1.5% increase in the
centreline velocity compared to 0.8% obtained from numerical simulation
Markers of inflammation in patients with psoriasis vulgaris and psoriatic arthritis
Introduction: The pathogenesis of psoriasis is complex. Genetic factors have a basic role, followed by immunological disturbances, which have been found to provoke a chronic inflammatory process affecting the skin and joints. The study aimed to establish and analyze the relationship between the inflammatory manifestations and vitamin D status in the patients with psoriasis.Patients and methods: We investigated 113 patients with moderate or severe psoriasis, divided in two groups for analysis: presence of psoriasis without psoriatic arthritis (n=73) and with psoriatic arthritis (n=40). Clinical data for inflammation were assessed by Psoriasis Area and Severity Index (PASI). At hospital admission samples were collected for C-reactive protein (CRP) and blood count, as well as for 25-hydroxyvitamin D, 25(OH)D. The serum levels of 25(OH)D were tested with immune fluorescent method in 92 patients.Results: The patients with psoriatic arthritis compared to psoriatic patients without arthritis had higher C-reactive protein (31.77 30.61 mg/l vs. 4.13 4.19 mg/l, p<0.0001) and PASI (35.20 11.31 vs. 28.82 12.51, p=0.012) but lower 25(OH)D (10.66 8.73 ng/ml vs. 12.98 6.23 ng/ml, p=0.004). The significant correlation was found between the level of CRP and 25(OH)D, r= -0.2631 (p=0.012) and CRP and PASI, r=0.1993 (p=0.036).Conclusion: The serum level of CRP and 25(OH)D, the vitamin D deficiency respectively, could be accepted as markers for worse health condition according to the clinical manifestations of psoriasis, as well as the comorbid diseases
Saliva application in oral and systemic diseases
Saliva is a noninvasive and accessible biofluid that permits early detection of oral and systemic diseases. Changes in saliva reflect the alterations in the blood and thus making saliva a suitable diagnostic tool. The use of saliva has many advantages, including simple and non-invasive sampling and easy, low-cost storage.Today salivary diagnostics is a promising tool for diagnostic processes and clinical monitoring. Saliva is used to detect illicit drugs, alcohol, to measure hormone levels, and in the diagnosis of wide range systemic diseases such as cardiovascular, infectious, renal, endocrine diseases, some types of cancer as well as nonsystemic oral diseases.The current review presents a critical overview of saliva as a promising tool for the development of valuable salivary biomarkers, their relevance to the prognosis, diagnosis and management of systemic and oral diseases. Development of point-of-care testing based on saliva samples as a screening tool will also support the diagnostic process in near future
Vitamin D status in patients with psoriasis
Introduction: Vitamin D may act as immune modulator in psoriasis and be related with disease characteristics. Our study aimed to evaluate the vitamin D status in patients admitted for diagnostics or exacerbation of psoriasis.Material and methods: 92 patients (50 male, 42 female, mean age 55 years) were included in analysis. Disease severity was assessed by Psoriasis Area and Severity Index (PASI). Type of disease was classified according to age at presentation as early (up to 40 years) and late (above 40 years). Serum levels of 25-hydroxyvitamin D, 25(OH)D, were tested with immune fluorescent method (ADVIA Centaur Vitamin D Total, Siemens).Results: The mean level of 25(OH)D in psoriatic patients was 12.07 ng/ml (30.18 nmol/l), found at low limit of insufficiency; related 95% CI range was 10.55 - 13.60 ng/ml (26.38 - 33.99 nmol/l). A total of 45 of 92 patients (48.9%) had vitamin D insufficiency (defined as 25 (OH) D level of 10 to 30 ng/ml), 44 patients (47.82%) had deficiency (< 10 ng/ml) and only in 3 patients 25(OH)D was assessed at level of sufficiency. Vitamin D level correlate with PASI (r=-0.508), but does not correlate with C-reactive protein. No significant difference in vitamin D status was observed in patients with obesity and early type 1 psoriasis.Conclusion: High prevalence (47.83%) of vitamin D deficiency in patients with moderate and severe psoriasis suspects the role of vitamin D in pathogenesis of disease exacerbation. Vitamin D therapeutic supplementation needs to be clarified by further studies
Basic methods for investigating and proving sickle-cell anemia
ΠΡΠ²Π΅Π΄Π΅Π½ΠΈΠ΅: Π‘ΡΡΠΏΠΎΠ²ΠΈΠ΄Π½ΠΎ-ΠΊΠ»Π΅ΡΡΡΠ½Π°ΡΠ° Π°Π½Π΅ΠΌΠΈΡ (Π‘ΠΠ) Π΅ Π³Π΅Π½Π΅ΡΠΈΡΠ½ΠΎ Π΄Π΅ΡΠ΅ΡΠΌΠΈΠ½ΠΈΡΠ°Π½ΠΎ Π·Π°Π±ΠΎΠ»ΡΠ²Π°Π½Π΅, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ²Π°ΡΠΎ ΡΠ΅ΡΠΈΠΎΠ·Π΅Π½ ΠΎΠ±ΡΠ΅ΡΡΠ²Π΅Π½ Π·Π΄ΡΠ°Π²Π΅Π½ ΠΏΡΠΎΠ±Π»Π΅ΠΌ Π½Π΅ ΡΠ°ΠΌΠΎ Π·Π° ΡΡΡΠ°Π½ΠΈΡΠ΅ Ρ ΡΡΠ°Π΄ΠΈΡΠΈΠΎΠ½Π½ΠΎ Π²ΠΈΡΠΎΠΊΠ° ΡΠ΅ΡΡΠΎΡΠ° (ΠΡΡΠΈΠΊΠ°, ΠΠ·ΠΈΡ, ΠΠΌΠ΅ΡΠΈΠΊΠ°, Π‘ΡΠ΅Π΄ΠΈΠ·Π΅ΠΌΠ½ΠΎΠΌΠΎΡΠΈΠ΅), Π½ΠΎ ΠΈ Π·Π° ΠΌΠ½ΠΎΠΆΠ΅ΡΡΠ²ΠΎ ΠΎΡ Π΅Π²ΡΠΎΠΏΠ΅ΠΉΡΠΊΠΈΡΠ΅ ΡΡΡΠ°Π½ΠΈ, ΠΊΡΠ΄Π΅ΡΠΎ ΡΠ΅ Π½Π°Π±Π»ΡΠ΄Π°Π²Π° Π½Π΅ΠΏΡΠ΅ΠΊΡΡΠ½Π°ΡΠΎ Π½Π°ΡΠ°ΡΡΠ²Π°Π½Π΅ Π½Π° ΡΠ΅ΡΡΠΎΡΠ°ΡΠ° Π½Π° ΡΠΎΠ²Π° Π·Π°Π±ΠΎΠ»ΡΠ²Π°Π½Π΅. Π¦Π΅Π»: ΠΠ° ΠΏΡΠ΅Π΄ΡΡΠ°Π²ΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΈ, ΠΈΠ·ΠΏΠΎΠ»Π·Π²Π°Π½ΠΈ Π·Π° ΡΠΊΡΠΈΠ½ΠΈΡΠ°Π½Π΅ ΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π½Π° Π‘ΠΠ. ΠΠΈΡΠΊΡΡΠΈΡ: ΠΠ΅ΡΠΎΠ΄ΠΈΡΠ΅, ΠΈΠ·ΠΏΠΎΠ»Π·Π²Π°Π½ΠΈ ΠΏΡΠΈ ΡΠΊΡΠΈΠ½ΠΈΡΠ°Π½Π΅ ΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠΈΡΠ°Π½Π΅ Π½Π° Π‘ΠΠ ΡΠ° Π΄Π²Π° ΠΎΡΠ½ΠΎΠ²Π½ΠΈ ΡΠΈΠΏΠ°: ΡΡΡΠΈΠ½Π½ΠΈ ΠΈ Π²ΠΈΡΠΎΠΊΠΎ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΠ·ΠΈΡΠ°Π½ΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΈ. Π ΡΡΠΈΠ½Π½ΠΈΡΠ΅ ΡΠ΅ΡΡΠΎΠ²Π΅ Π²ΠΊΠ»ΡΡΠ²Π°Ρ ΠΠΠ, Π±ΠΈΠΎΡ
ΠΈΠΌΠΈΡΠ½ΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Π·Π° Π΄ΠΎΠΊΠ°Π·Π²Π°Π½Π΅ Π½Π° Ρ
Π΅ΠΌΠΎΠ»ΠΈΠ·Π° in vivo, ΠΈΠ·ΡΠ»Π΅Π΄Π²Π°Π½Π΅ Π½Π° ΡΡΠΈΠ½Π°, ΠΊΠ°ΠΊΡΠΎ ΠΈ ΡΠΊΡΠΈΠ½ΠΈΡΠ°ΡΠΈΡΠ΅ ΡΠ΅ΡΡΠΎΠ²Π΅ Π·Π° Π΄ΠΎΠΊΠ°Π·Π²Π°Π½Π΅ Π½Π°Π»ΠΈΡΠΈΠ΅ΡΠΎ Π½Π° HbS - ΡΠ΅ΡΡΠΎΠ²Π΅ Π·Π° ΡΠ°Π·ΡΠ²ΠΎΡΠΈΠΌΠΎΡΡ, ΡΠ΅ΡΡΠΎΠ²Π΅, ΠΏΡΠ΅Π΄ΠΈΠ·Π²ΠΈΠΊΠ²Π°ΡΠΈ ΠΏΡΠΎΠΌΡΠ½Π° Π²ΡΠ² ΡΠΎΡΠΌΠ°ΡΠ° Π½Π° Π΅ΡΠΈΡΡΠΎΡΠΈΡΠΈΡΠ΅ ΠΈ Π΄Ρ. ΠΡ ΠΈΠ·ΠΊΠ»ΡΡΠΈΡΠ΅Π»Π½ΠΎ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ Π·Π° ΠΏΠΎΡΠ²ΡΡΠΆΠ΄Π°Π²Π°Π½Π΅ Π½Π° Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π΅ ΠΈΠ·ΠΏΠΎΠ»Π·Π²Π°Π½Π΅ΡΠΎ Π½Π° Π²ΠΈΡΠΎΠΊΠΎ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΠ·ΠΈΡΠ°Π½ΠΈ ΡΠ΅Ρ
Π½ΠΈΠΊΠΈ Π·Π° ΡΠ°Π·Π΄Π΅Π»ΡΠ½Π΅ Π½Π° Π±Π΅Π»ΡΡΡΠΈ ΠΊΠ°ΡΠΎ Π΅Π»Π΅ΠΊΡΡΠΎΡΠΎΡΠ΅Π·Π° ΠΈ Π²ΠΈΡΠΎΠΊΠΎΠ΅ΡΠ΅ΠΊΡΠΈΠ²Π½Π° ΡΠ΅ΡΠ½Π° Ρ
ΡΠΎΠΌΠ°ΡΠΎΠ³ΡΠ°ΡΠΈΡ (HPLC), ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΠΈ Π°Π±Π½ΠΎΡΠΌΠ½ΠΈΡΠ΅ Ρ
Π΅ΠΌΠΎΠ³Π»ΠΎΠ±ΠΈΠ½ΠΎΠ²ΠΈ Π²Π°ΡΠΈΠ°Π½ΡΠΈ. ΠΠ° Π½ΡΠΆΠ΄ΠΈΡΠ΅ Π½Π° ΠΏΡΠ΅Π½Π°ΡΠ°Π»Π½Π°ΡΠ° Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ° ΡΠ΅ ΠΈΠ·ΠΏΠΎΠ»Π·Π²Π° ΠΈ ΠΠΠ Π°Π½Π°Π»ΠΈΠ· Π·Π° Π΄ΠΎΠΊΠ°Π·Π²Π°Π½Π΅ Π½Π° ΡΠΎΡΠΊΠΎΠ²Π° ΠΌΡΡΠ°ΡΠΈΡ Π² Π³Π΅Π½Π° Π·Π° Π±Π΅ΡΠ° Π²Π΅ΡΠΈΠ³Π°ΡΠ° Π½Π° Π³Π»ΠΎΠ±ΠΈΠ½ΠΎΠ²Π°ΡΠ° ΠΌΠΎΠ»Π΅ΠΊΡΠ»Π°. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅: ΠΠ΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ Π΅ Π΄Π° ΡΠ΅ ΠΏΠΎΠ·Π½Π°Π²Π°Ρ ΡΠ°Π·Π»ΠΈΡΠ½ΠΈΡΠ΅ Π²ΠΈΠ΄ΠΎΠ²Π΅ ΠΌΠ΅ΡΠΎΠ΄ΠΈ Π·Π° ΡΠΊΡΠΈΠ½ΠΈΡΠ°Π½Π΅ ΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π½Π° Π‘ΠΠ, Π·Π° Π΄Π° Π΅ ΠΌΠ°ΠΊΡΠΈΠΌΠ°Π»Π½ΠΎ Π΅ΡΠ΅ΠΊΡΠΈΠ²Π΅Π½ ΠΈ Π±ΡΡΠ· Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ½ΠΈΡΡ ΠΏΡΠΎΡΠ΅Ρ ΠΏΡΠΈ ΡΠΎΠ²Π° ΡΠ°Π·ΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΎ ΠΈ Π½Π΅ ΡΡΠ΄ΠΊΠΎ ΡΠ΅ΠΆΠΊΠΎ ΠΏΡΠΎΡΠΈΡΠ°ΡΠΎ Π½Π°ΡΠ»Π΅Π΄ΡΡΠ²Π΅Π½ΠΎ Π·Π°Π±ΠΎΠ»ΡΠ²Π°Π½Π΅.Introduction: The sickle-cell anaemia (SCA) is a genetically determined disease, that is a major public health issue amongst not only the countries where it is traditionally quite common (Africa, Asia, America and the Mediterranean), but also the majority of European countries, where a significant increase of the frequency of the disease is observed. Aim: To present methods used for screening and diagnose of SCA. Discussion: The methods used for screening and diagnose of SCA can be classified into two main categories - routine ones and highly specialised laboratory methods. The routine tests include complete blood count, biochemical parameters to prove in vivo haemolysis, urine tests and the screening tests for presence of HbS e.g. sickling tests and solubility tests. In order to confirm the diagnosis of SCA the usage of protein separation techniques such as electrophoresis and high-performance liquid chromatography (HPLC) for detection of abnormal hemoglobin variants is of high importance. Concerning prenatal diagnostics DNA analysis is also used for detection of point mutation in the fetus beta gene of globin molecule. Conclusion: In order to ensure with maximum of effectiveness the diagnostic process of this common hereditary disease, a good knowledge of all available screening and diagnostic methods is needed
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