1,716 research outputs found

    Fetal alcohol spectrum disorders: a review of interventions for prevention and management in Indigenous communities

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    This resource sheet provides estimates on the prevalence of fetal alcohol spectrum disorders in the general and Indigenous populations of Australia, and reviews the local and international evidence on the effectiveness of programs that aim to prevent or alleviate this group of disorders. Introduction This resource sheet defines fetal alcohol spectrum disorders and provides currently available estimates of their prevalence in the overall Australian population and in the Indigenous population. The current recommendation of the National Health and Medical Research Council on the consumption of alcohol during pregnancy is also provided. Where appropriate, comparisons are made with other countries. The resource sheet reviews the Australian and international literature published since 1990 on the effectiveness of programs that aim to prevent fetal alcohol spectrum disorders or to alleviate its effects. Evidence on the effectiveness of Australian and Indigenous specific programs is also assessed, including those programs that have been developed and implemented in partnership with Indigenous Australians

    Phenotypic and Functional Properties of Tumor-Infiltrating Regulatory T Cells

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    My Response to Ramseyer’s Effort to Deny the History of Japanese Military Sexual Slavery

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    The main objective of this paper is to critically evaluate as many of Ramseyer’s arguments as possible included in his 2022 paper. It consists of three sections in addition to the introduction and concluding remarks. The first section summarizes the expanded literature that interpreted the “comfort women” system as sexual slavery, judgments, and recommendations to the Japanese government given by scholars, international human rights organizations and the legislative branches of four Western countries. Since Ramseyer published his article denying the “comfort women” system as sexual slavery without introducing this literature, we cannot consider his article as an academic work. The second section critically evaluates Ramseyer’s unacceptable and untenable arguments that Japanese and Korean “comfort women” were commercial sex workers with labor contracts rather than sexual slaves. The third section critically evaluates Ramseyer’s severe criticisms of the Korean council and its redress activities

    On the frequency of permutations containing a long cycle

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    A general explicit upper bound is obtained for the proportion P(n,m)P(n,m) of elements of order dividing mm, where n−1≀m≀cnn-1 \le m \le cn for some constant cc, in the finite symmetric group SnS_n. This is used to find lower bounds for the conditional probabilities that an element of SnS_n or AnA_n contains an rr-cycle, given that it satisfies an equation of the form xrs=1x^{rs}=1 where s≀3s\leq3. For example, the conditional probability that an element xx is an nn-cycle, given that xn=1x^n=1, is always greater than 2/7, and is greater than 1/2 if nn does not divide 24. Our results improve estimates of these conditional probabilities in earlier work of the authors with Beals, Leedham-Green and Seress, and have applications for analysing black-box recognition algorithms for the finite symmetric and alternating groups

    Different but equal: equal value a guide to comparing jobs

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    This is a guide to assist comparison of jobs for determining equal valu

    Enhancement of cartilage repair through the addition of growth plate chondrocytes in an immature skeleton animal model

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    Background: The treatment of articular cartilage damage is a major clinical problem. More often, this clinical issue affects children, which forces doctors to find the best treatment method. Methods: The aim of this experimental study on 2-month-old Landrace pigs was to compare the results of two cartilage defect treatments: (1) filling the cartilage defect with a scaffold incubated with bone marrow aspirate supplemented with growth plate chondrocytes (the CELLS group) and (2) filling the cartilage defect with an empty scaffold implanted after drilling the subchondral bone (the CTRL group). The treatment outcomes were assessed macroscopically and microscopically. Results: Based on the macroscopic evaluation, all animals showed a nearly normal morphology, with an average of 9.66/12 points (CTRL) and 10.44/12 points (CELLS). Based on the microscopic evaluation, 1 very good result and 8 good results were obtained in the CTRL group, with an average of 70.44%, while 5 very good results and 4 good results were obtained in the CELLS group, with an average of 79.61%. Conclusions: (1) Growth plate chondrocytes have high chondrogenic potential and thus offer new possibilities for cartilage cell therapy. (2) The implantation of a scaffold loaded with bone marrow-derived MSCs (mesenchymal stem cells) and growth plate chondrocytes into a cartilage defect is a good therapeutic method in immature patients. (3) Cartilage repair based on a scaffold with bone marrow aspirate-derived cells supplemented with autologous growth plate chondrocytes achieves better results than repair with marrow stimulation and a hyaluronic acid-based scaffold (overall microscopic rating). (4) Chondrocyte clustering is a manifestation of the cartilage repair process but requires further observation

    Radioactive Contamination at Dayton Canyon from the Santa Susana Filed Laboratory

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    Radioactive Contamination at Dayton Canyon from the Santa Susana Filed Laboratory was a report that was deeply flawed as the result of the Department of Toxic Substances Control (DTSC) misrepresenting the underlying data , as well as poor protection levels and an a priori assumption that there can\u27t be contamination coming from Santa Susana Field Laboratory (SSFL). It should be rejected. Correspondence and context for this failed study, and the ways the Committee to Bridge the Gap and its researchers were led astray by aforementioned parties, is documented in detail here. This research was completed money allocated during Round 6 of the Citizens’ Monitoring and Technical Assessment Fund (MTA Fund). Clark University was named conservator of these works. If you have any questions or concerns please contact us at [email protected]://commons.clarku.edu/bridge_gap/1002/thumbnail.jp

    Radioactive Contamination at Runkle Ranch from the Santa Susana Field Laboratory

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    Runkle Ranch is the site of a proposed residential development in Simi Valley. Because it is located near to, and below, the Santa Susana Field Laboratory ((SFL), a nuclear reactor and rocket testing and development facility with significant radioactive and chemical contamination, the developer arranged for a series of tests of soil and other environmental media. SSFL is operated for the U.S. government by the Rocketdyne Division of the Boeing Company. This report examines the results of the soil testing for radioactivity. The Environmental Impact Report (EIR) that supported the approval of the project briefly addressed the potential for contaminants from SSFL to have impacted the Runkle Ranch land and concluded that this was not an issue. The EIR1 noted that background levels of strontium-90 are “about 0.1 pico Curie per gram (pCi/g)” and went on to describe sampling results for the Runkle property: Previous assessments of strontium-90 and tritium within the vicinity of the [Runkle Canyon] Specific Plan Area included a survey conducted by QST Environmental, Inc. in 1998. This study was conducted to determine if nuclear 1 This and the following two quotes are from pp. 4.6-6 and 4.6-7 of the EIR. 2 reactor operations at the SSFL facility had impacted soil at the site through surface water runoff. Four soil samples at three were collected and analyzed for cesium-137, strontium-90 and tritium. One of the locations was within a natural drainage channel flowing from the locale of the SSFL facility towards the northeastern portion of the Specific Plan Area. The results of the survey indicated that the surface soil contained concentrations of cesium-137 and strontium-90 that exceeded background levels established by the EPA. Because of the initial findings, followup sampling was initiated. As the EIR states: Consequently, further testing was indicated. Tritium was also detected in the samples, but at concentrations below the EPA background levels. A limited radiation survey was conducted during subsequent testing and analysis in the Phase I ESA for the 550-acre parcel referenced in this section. This assessment found that radiation levels were within normal background levels. Tritium and strontium-90 were not detected in any of the soil and groundwater samples at levels above normal background levels or at levels considered to pose a health risk. (emphasis added). This conclusion is puzzling, because the actual measurements being cited for the proposition that none were above background nor above levels considered to pose a health risk show precisely the opposite. Rather than none of the samples being above background or health risk levels, ALL 58 of the 1999 follow-up strontium measurements exceeded the 0.1 pCi/gram background figure cited in the EIR (as we shall see, that figure is actually twice background), and virtually all exceed the EPA’s Preliminary Remediation Goals (PRGs). This research was completed money allocated during Round 6 of the Citizens’ Monitoring and Technical Assessment Fund (MTA Fund). Clark University was named conservator of these works. If you have any questions or concerns please contact us at [email protected]://commons.clarku.edu/bridge_gap/1001/thumbnail.jp
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