A Review and Analysis of Traffic Data Sources

Transportation is essential for economic and social development, and vehicle flow data can be used for safety monitoring, pollution analysis, and traffic flow management. Unfortunately, traffic management and control centres do not always comply with codified standards, making it difficult to obtain up-To-date data. This paper analyses open traffic datasets and Italian public traffic data sources available online, providing a knowledge base for transportation managers and researchers. Open traffic datasets are dimensionality-reduced and clustered. An event with 209,135 visitors is used to benchmark the public data sources, the time series of traffic flows are decomposed and a regression tree is used to identify different periods. The results suggest that the available Italian sensor grid is not fine enough to identify all incoming and outgoing traffic, more infrastructure investments are required or the available measurements should be coupled with other evaluation approaches capable of extending the punctual data through mathematical means

Ecotoxicity of Plastics from Informal Waste Electric and Electronic Treatment and Recycling

Plastic materials account for about 20% of waste electrical and electronic equipment (WEEE). The recycling of this plastic fraction is a complex issue, heavily conditioned by the content of harmful additives, such as brominated flame retardants. Thus, the management and reprocessing of WEEE plastics pose environmental and human health concerns, mainly in developing countries, where informal recycling and disposal are practiced. The objective of this study was twofold. Firstly, it aimed to investigate some of the available options described in the literature for the re-use of WEEE plastic scraps in construction materials, a promising recycling route in the developing countries. Moreover, it presents an evaluation of the impact of these available end-of-life scenarios on the environment by means of the life cycle assessment (LCA) approach. In order to consider worker health and human and ecological risks, the LCA analysis focuses on ecotoxicity more than on climate change. The LCA evaluation confirmed that the plastic re-use in the construction sector has a lower toxicity impact on the environment and human health than common landfilling and incineration practices. It also shows that the unregulated handling and dismantling activities, as well as the re-use practices, contribute significantly to the impact of WEEE plastic treatments

New and Reconditioned Electrical and Electronic Equipment. How does change the environmental performance?

The scope of this study, carried out within the LIFE12 ENV/IT001058 - "WEEENmodels" project, was to compare the environmental performance of the life cycle of new electrical and electronic equipment (EEE) and the reused one through the Life Cycle Assessment (LCA) methodology. Different set of replaced components have been evaluated in order to understand which determines the best solution. Finally, both attributional and consequential LCI (Life Cycle Inventory) modelling have been implemented. A representative product has been considered for each WEEE group, assuming that it generates the same environmental damage of the other products belonging to the same category. In particular, the following representative products have been selected: refrigerator (R1), washing machine (R2), cathode ray tube (CRT) (R3), laptop (R4) and fluorescent lamp (R5). In addition, in the use phase, lower performance of reconditioned EEE has been taken into account, e.g. higher energy consumptions. The lifespan of the reused product has been supposed to be equal to half-life time of an equivalent new product. This study evaluated different set of replaced components for each WEEE category in order to examine how the environmental performance can vary adopting different maintenance choices in the reconditioning step. In particular, Scenario A represents the set of replaced components, which damage more frequently; Scenario B is just an alternative set of replaced components. The environmental comparison between new and reused WEEE, adopting attributional LCI modelling, showed that Scenario B produces a damage decrease for all WEEE categories. Moving on the consequential LCI modelling, the environmental comparison highlighted for both scenarios a considerable damage reduction for the reused EEE respect the new one. In addition, Scenario B determined the best environmental performance. Furthermore, for the reused R1, R2, R3 the analysis of results carried out environmental credits. This is due to the avoided burdens associated to the manufacturing of the new EEE, since the system boundaries have been enlarged until to considering the avoided production of the new product. Attributional and consequential LCI modelling performed different LCIA results. Following the methodological guidance for the identification of the most adequate LCI modelling framework presented by Laurent et al., 2014, it would recommend to adopt consequential LCI modelling. But we suggest to LCA practitioner to focus also the attention on the request of who commissioned the project, which often in the waste field are local administrations. Generally, they wants a snapshot of the real effects that waste management policies provoke on human health and environment. For this reason, attributional LCI modelling would be the proper LCI modelling to achieve this scope. Considering this LCI modelling the Scenario B determines the best environmental performance

Preparation for reuse activity of waste electrical and electronic equipment: Environmental performance, cost externality and job creation

The European Waste Electrical and Electronic Equipment system introduced measures to encourage both the reduction of the amount of electronic waste and its separation to prepare for reuse. The aim of this study is compare the environmental performance, cost externality and job creation of the whole life cycle of new and reconditioned electrical and electronic equipment by adopting Life Cycle Assessment methodology. Five electrical and electronic equipment categories were investigated and the data collection was made on an Italian context. The refurbishing of breakdown electrical and electronic equipment was assessed by considering different sets of faulty components (Scenario A and B) and a total of 25 scenarios were studied. Moreover, both attributional and consequential life cycle inventory modelling framework were adopted to represent the investigated scenarios. The outcomes highlighted that the preparation for reuse process leads to obtaining a sustainable electronic device than the new one, depending on which set of components are replaced. Adopting Scenario B with the attributional model, the environmental damage of reconditioned electrical and electronic equipment decreases compared to the new one. Conversely, the consequential approach determines an environmental credit for all repaired electronic devices except for one category; in particular, Scenario A produced the largest environmental advantage. The analyses of external costs and social aspects confirm that the preparation for reuse activity allows to obtain a more sustainable product than a new one. For these two latter aspects, the results showed a turnaround passing from attributional model to consequential one. Noting the variability in results adopting both different life cycle inventory modelling framework and set of replaced components, the Life Cycle Assessment practitioner, that conducted the study, should help the decision-makers to determine which scenario is more sustainable accomplishing an adequate choice

An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production

Increase of the expression of γ-globin gene and high production of fetal hemoglobin (HbF) in β-thalassemia patients is widely accepted as associated with a milder or even asymptomatic disease. The search for HbF-associated polymorphisms (such as the XmnI, BCL11A and MYB polymorphisms) has recently gained great attention, in order to stratify β-thalassemia patients with respect to expectancy of the first transfusion, need for annual intake of blood, response to HbF inducers (the most studied of which is hydroxyurea)

CANCER RISK FROM HEAVY METAL EXPOSURE IN RECYCLING WASTE OF ELECTRICAL AND ELECTRONIC EQUIPMENT: PRELIMINARY RESULTS FROM THE WEEENMODELS EUROPEAN LIFE PROGRAM

Background and objectives: When electrical and electronic equipment reaches its end of life, it becomes ‘Waste Electrical and Electronic Equipment’ (WEEE). The growing amount of this type of waste has posed significant challenges to waste management, since WEEE contains a whole range of toxic chemicals having relevant environmental and health implications. The WEEE life cycle may expose the general population and workers to various toxic chemicals, such as heavy metals. We conducted a health risk assessment to evaluate the cancer risk derived from environmental and occupational exposure to trace elements from different recycling procedures (electronic scrap in blister copper, treatment of metals recovery in copper smelter, treatment of shredding, pyrometallurgical treatment of Li-ion battery). We considered the typical production of WEEE in a municipality of 150.0000 inhabitants, where a Life Cycle assessment (LCA) was carried out. Methods: Outdoor (1km2 around a WEEE treatment plant) and indoor (factory volume of 3200m3) emissions generated from the above-mentioned procedures were computed, to perform a health risk assessment for occupationally-exposed workers and for the general population around the plant. Dose of the heavy metals cadmium, nickel, arsenic inhaled by the potentially exposed population was estimated using the values obtained through a toxicological model. Cancer risk due to inhalation was calculated using the method proposed by the California Office of Environmental Health and Hazard Assessment. Results and Conclusions: For the heavy metals considered, generated from WEEE treatment, these preliminary results show negligible cancer risk for the general population. On the converse, some risks may be present for occupational exposures linked to specific procedures (from cancer risk of 1,42x10-3 for men working in shredding procedure and exposed to nickel to cancer risk of 4,68x10- 4 for women working with electronic scrap and exposed to arsenic)

Assessing Cancer Risk from Heavy Metals in Recycling Waste Electrical and Electronic Equipment: Preliminary Results from the WEENMODELS European Life Programme

Introduction The growing amount of waste derived from electrical and electronic equipment (WEEE) poses significant challenges to waste management, due to the presence of toxic chemicals with environmental and health implications for the general population and for occupationally-exposed workers. Methods Based on an toxicological and epidemiologic evaluation, we carried out a health risk assessment to evaluate the cancer risk deriving from environmental and occupational exposure to heavy metals released during different WEEE recycling procedures (electronic scrap in blister copper, treatment of metals recovery in copper smelter, treatment of shredding, pyrometallurgical treatment of Li-ion battery). We considered the typical WEEE production in a municipality of 150.0000 inhabitants, carrying out a Life Cycle Assessment. Outdoor (1 square km around a treatment plant) and indoor (for a factory volume of 3200 m3) emissions generated during the WEEE recycling procedures were computed. In particular, we estimated the amount of Cd, Ni and As inhaled by the potentially exposed population. We computed the cancer risk due to inhalation of these heavy metals in residents and workers using the methodology proposed by the California Office of Environmental Health and Hazard Assessment Results For the metals considered, our results showed negligible cancer risk (from 2,21x10-11 to 4,31x10-08) for the general population around the plant. On the converse, occupational exposures linked to specific procedures were associated with a cancer risk of 1,42x10-3 for workers in the shredding procedures mainly due to Ni exposure, and of 4,68x10-4 for workers with electronic scrap and exposed to As. Conclusions Based on our preliminary results from an integrated toxicological and epidemiologic approach, WEEE life cycle may be linked to health risks for workers in the recycling procedures, while it does not seem to adversely affect health of the general population around the treatment plants

Longitudinal follow‐up of patients with thalassaemia intermedia who started transfusion therapy in adulthood: a cohort study

SummaryWe longitudinally evaluated the effects of regular blood transfusions (BTs), in the real‐life context of the Myocardial Iron Overload in Thalassaemia network, in patients with thalassaemia intermedia (TI). We considered 88 patients with TI (52 females) who started regular BTs after the age of 18 years. Magnetic resonance imaging was used to quantify iron overload and biventricular function. For 56·8% of the patients there were more than two indications for the transition to regular BTs, with anaemia present in 94·0% of the cases. A significant decrease in nucleated red blood cells, platelets, lactate dehydrogenase, bilirubin, and uric acid levels was detected 6 months after starting regular BTs. After the transition to the regular BT regimen there was a significant increase only in the frequency of hypothyroidism and osteopenia, and a significant decrease in liver iron and cardiac index. The percentage of chelated patients increased significantly after starting regular BTs. The decision to regularly transfuse patients with TI may represent a way to prevent or slow down the natural progression of the disease, despite the more complex initial management