Sustainable Carbododiimine and Triazine Reagents as Collagen Cross-Linking Agents in the Presence of PAMAM Dendrimers

This work reports a general outline on sustainable technologies for the stabilization of collagen and comparative study of 1-ethyl-3-(3-dimethyla-minopropyl)carbodiimide (EDC) versus 4-(4,6-dimethoxy [1, 3, 5] triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM) as cross-linking agents of collagen powder. The cross-linking efficiency of these agents on collagen matrixes in the presence of different polyamidoamine dendrimers (PAMAM) has been tested in order to determine the influence of steric hindrance and aminic groups abundance