Infecção experimental em suínos jovens com Leptospira interrogans sorovar wolffi: determinação de parâmetros bioquímicos Experimental infection by Leptospira interrogans serovar wolffi in young pigs: determination of biochemical parameters

Um estudo sobre infecção experimental foi realizado em oito suínos, com idade média de 90 dias, machos castrados, da raça Wessex, e distribuídos em dois grupos de quatro suínos cada. Durante 36 dias, foram analisadas as alterações bioquímicas nos soros dos suínos dos dois grupos. O Grupo I foi mantido como testemunho e recebeu 5,0mL de solução fisiológica estéril por via intravenosa (veia cava craniana) e, no Grupo II, os suínos foram inoculados pela mesma via com 5,0mL de cultura de Leptospira interrogans sorovar wolffi , amostra L-10 selvagem isolada de tatu (Dasypus novemcinctus), contendo 1,0 x 10(8) leptospiras/mL. A partir do terceiro dia após a inoculação e em intervalos de 72 horas até o décimo oitavo dia, foram feitas coletas de sangue, sem anticoagulante, dos animais inoculados e testemunhas. Os parâmetros bioquímicos analisados foram: bilirrubina total, direta e indireta, ácidos graxos, glicose e proteínas plasmáticas. Foi detectado um aumento da bilirrubina direta no terceiro dia e um aumento no sexto dia da bilirrubina total e indireta após a inoculação. As dosagens de glicose, ácidos graxos e proteínas plasmáticas apresentaram uma diminuição a partir do terceiro dia da inoculação. Com os resultados obtidos, pode-se concluir que o aumento das taxas de bilirrubinas levam a uma definição de um diagnóstico de hemólise aguda, e que a hipoglicemia, a hipolipidemia e a hipoproteinemia podem estar relacionadas com lesões hepáticas e a uma septcemia.Todas as dosagens em todos os animais retornaram aos seus valores normais a partir do décimo quinto dia.<br>Eight, 90 days old pigs, of the Wessex lineage all castrated male were used in experiment, divided into two groups of four animals. Biochemical alterations in the serum of the animals were analyzed in both groups during 36 days. Control (Group I) received 5.0mL of a 0.9% sterile sodium chloride solution by intracranial vein injection; Group II animals were inoculated by the same way with 5.0mL of a cell culture containing 1.0x10(8)cells/mL of Leptospira interrogans sorovar wolffi, wild strain L-10, isolated from a wild especies of brazilian "armadillo" (Dasypus novemcinctus). Three days after inoculation, blood was collected without anticoagulant; the same process was repeated at 72 hours intervals during eighteen days in both, control and experimental groups. Quantitative biochemical parameters were direct, indirect and total bilirubin, fatty acids and serum proteins. The experimental animals showed an increase of direct bilirubin three days after inoculation. Increases in indirect and total bilirubin were, also, observed after six days. Glucose, fatty acids and serum proteins decreased after the third day of inoculation. In conclusion, the increase in bilirubin levels could be due to acute hemolysis; hypoglycemia, hypolipidemia and hypoproteinemia that could be related to hepatic lesions and septicemia. All parameters returned to normal levels after fifteen days, in all animals tested

Neutral Strange Particle Production in Neutrino and Antineutrino Charged-Current Interactions on Neon

A study has been made of neutral strange particle production in νμNe and ν̄μNe charged-current interactions at a higher energy than any previous study. The experiment was done at the Fermilab Tevatron using the 15-ft. bubble chamber, and the data sample consists of 814(154) observed neutral strange particles from 6263(1115) ν(ν̄) charged-current events. For the ν beam (average event energy Eν=150 GeV), the average multiplicities per charged-current event have been measured to be 0.408±0.048 for K0, 0.127±0.014 for Λ, and 0.015±0.005 for Λ̄, which are significantly greater than for lower-energy experiments. The dependence of rates on kinematical variables has been measured, and shows that both K0 and Λ production increase strongly with Eν, W2, Q2, and yB. Compared to lower-energy experiments, single-particle distributions indicate that there is much more K0 production for xF>-0.2, and the enhanced Λ production spans most of the kinematic region. Λ̄ production is mostly in the region xF-0.2 there is a significant excess of Λ production over the model's prediction. The Λ hyperons are found to be polarized in the production plane. © 1994 The American Physical Society.086 auteursSCOPUS: ar.jinfo:eu-repo/semantics/publishe

Argumentation in Foreign Policy Settings

This is a study of argumentation in three different kinds of high level, confidential, foreign policy settings: a collegial setting, a bureaucratic setting, and a bargaining setting. The causal and value assertions of the participants were coded using the detailed records of these three settings. The data show to be inadequate a defense/ attack model of argumentation in which the participants support their own arguments to make them resistant to attack, while attacking the weak spots in others'stated positions. In fact, there are few assertions which are supported by specific evidence, almost no mutually supported causal arguments, and the assertions which were attacked were no less emphasized than the assertions which were not attacked. More in accord with the data is the novel-arguments approach in which the key factor in persuasive argumentation is the development of arguments which others have not already taken into account.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67391/2/10.1177_002200277702100410.pd